Devices descending from DEN100017
12 later devices reach Lipflow Thermal Pulsation System (Formerly Manual Mini System) through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K161357 | LipiFlow Thermal Pulsation System | Tearscience, Inc. | 2016 | 7 | 1 |
| +1 | K133127 | Lipiflow Thermal Pulsation System | Tearscience, Inc. | 2013 | 10 | 2 |
| +1 | K112704 | Lipiflow Thermal Pulsation System | Tearscience, Inc. | 2011 | 11 | 2 |
| +2 | K213045 | TearCare System | Sight Sciences, Inc. | 2021 | 5 | — |
| +2 | K192623 | LipiFlow Thermal Pulsation System | Tearscience, Inc. | 2019 | 1 | — |
| +2 | K172645 | iLux Instrument, iLux Disposable | Tear Film Innovations, Inc. | 2017 | 2 | — |
| +3 | K240512 | Tixel i (TXLI0001) | Novoxel, Ltd. | 2024 | 0 | — |
| +3 | K231084 | TearCare MGX System | Sight Sciences, Inc. | 2023 | 4 | — |
| +3 | K200400 | Systane iLux2 | Tear Film Innovations, Inc. | 2020 | 0 | — |
| +4 | K242786 | TearCare MGX System | Sight Sciences, Inc. | 2025 | 2 | — |
| +5 | K252409 | TearCare MGX System | Sight Sciences, Inc. | 2026 | 1 | — |
| +6 | K262479 | TearCare System | Sight Sciences, Inc. | 2026 | 0 | — |