Devices descending from K003422
65 later devices reach Edta Root Canal Cleanser through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K032361 | Endopure Root Canal Cleanser | Dentsply Intl. | 2004 | 64 | — |
| +2 | K071363 | Waterlase and Waterlase MD | Biolase Technology, Inc. | 2008 | 28 | — |
| +2 | K053167 | Biopure Mtad Root Canal Cleanser | Dentsply Intl., Inc. | 2005 | 63 | — |
| +3 | K193357 | V-Mix | Inter-Med/Vista Dental Products | 2020 | 1 | — |
| +3 | K123538 | Epien Root Canal Cleanser | Epien Medical, Inc. | 2013 | 0 | — |
| +3 | K112250 | CHX=CHX Plus | Inter-Med, Inc. | 2011 | 1 | — |
| +3 | K103244 | Qmix 2IN1 Endodontic Irrigating Solution | Dentsply Intl., Inc. | 2011 | 7 | — |
| +3 | K101658 | Waterlase MD Turbo Plus Model 7200XXX | Biolase Technology, Inc. | 2010 | 25 | 1 |
| +3 | K092232 | Modification to:Vashe Wound Cleansing System, Model 9000-0014 | Puricore, Inc. | 2009 | 16 | — |
| +3 | K091922 | Waterlase C100, Model 7100104 | Biolase Technology, Inc. | 2009 | 0 | — |
| +3 | K090181 | Waterlase MD | Biolase Technology, Inc. | 2009 | 26 | — |
| +3 | K070401 | Endo-CHX | Essential Dental Systems, Inc. | 2007 | 2 | — |
| +3 | K061689 | Aquatine EC Endodontic Cleanser | Puricore, Inc. | 2006 | 11 | — |
| +3 | K060901 | Vashe Wound Cleansing System | Sterilox Technologies, Inc. | 2006 | 0 | — |
| +4 | K211813 | Triton | Inter-Med / Vista Dental | 2021 | 0 | — |
| +4 | K193409 | Vista Rinse, Vista Rinse Plus | Inter-Med/Vista Dental Products | 2020 | 2 | — |
| +4 | K190319 | Waterlase Laser System Family | Biolase, Inc. | 2019 | 19 | — |
| +4 | K161669 | Waterlase Express | Biolase, Inc. | 2016 | 21 | — |
| +4 | K160577 | PacEndo Chlorhexidine | Pac-Dent International, Inc. | 2016 | 0 | — |
| +4 | K150020 | Irritrol, EDS Combo-Rinse | Essential Dental Systesm, Inc. | 2015 | 0 | — |
| +4 | K141352 | Endocyn Root Canal Irrigation Solution | Oculus Innovative Sciences | 2014 | 0 | — |
| +4 | K140846 | Eds Combo-Rinse | Essential Dental Systems, Inc. | 2014 | 0 | — |
| +4 | K113693 | Nixall TM Wound and Skin Care | Seriously Clean, Ltd. | 2012 | 15 | — |
| +4 | K120377 | Adverl Evo ER: Yag Laser for Dentistry Mey-1-a | J. Morita USA, Inc. | 2012 | 2 | — |
| +4 | K082470 | Sodium Hypochlorite 3 & 6% Solution and 6% with Wetting Agents to Lower Surface Tension… | Inter-Med, Inc. | 2009 | 6 | 7 |
| +5 | K213428 | EdgePro | Biolase, Inc. | 2021 | 0 | — |
| +5 | K193656 | SkyPulse | Fotona D.O.O. | 2020 | 11 | — |
| +5 | K193661 | LightWalker Laser System Family | Fotona D.O.O. | 2020 | 8 | — |
| +5 | K180305 | Hychloderm Wound and Skin Care (Rx) and Hychloderm Wound and Skin Care (OTC) | Aquilabs Us, LLC | 2018 | 0 | — |
| +5 | K173163 | ChlorCid, ChlorCid V, ChlorCid Surf | Ultradent Products, Inc. | 2018 | 0 | — |
| +5 | K150664 | NeoLas | Sheaumann Laser, Inc. | 2015 | 1 | — |
| +5 | K151852 | PacEndo Sodium Hyprochlorite | Pac-Dent International, Inc. | 2015 | 0 | — |
| +5 | K142592 | CleanSmart Wound Cleanser | Simple Science, LLC | 2015 | 4 | — |
| +5 | K133542 | Puracyn Plus Skin and Wound | Innovacyn, Inc. | 2014 | 14 | — |
| +5 | K130180 | Cleanser Root Canal | Cerkamed Wojciech Pawlowski | 2013 | 0 | — |
| +6 | K254197 | Picasso Pro Diode Laser (002-00460) | CAO Group, Inc. | 2026 | 0 | — |
| +6 | K241791 | Medical Diode Laser Systems (GBOX-6H, GBOX-10D , GBOX-12D, GBOX-15D, VELAS Pro-30B15D… | Gigaalaser Company, Ltd. | 2025 | 1 | — |
| +6 | K234004 | Medical diode laser systems (CHARISMA, REGAL) | Reveal Lasers, Ltd. | 2025 | 1 | — |
| +6 | K232080 | Puracyn® Plus Antimicrobial Irrigation Solution | Innovacyn, Inc. | 2024 | 1 | — |
| +6 | K240179 | Medical Diode Laser (Model: L2) | Wuhan Pioon Technology Co., Ltd. | 2024 | 2 | — |
| +6 | K230274 | Medical Diode Laser (M2) | Wuhan Pioon Technology Co., Ltd. | 2023 | 2 | — |
| +6 | K221712 | Fotona XPulse Laser System Family (XPulse 1064 nm, XPulse 810 nm, XPulse 980 nm) | Fotona D.O.O. | 2022 | 1 | — |
| +6 | K202991 | Fotona XPulse Pro Laser Platform | Fotona D.O.O. | 2021 | 3 | — |
| +6 | K202985 | LightWalker Laser System Family | Fotona D.O.O. | 2021 | 7 | — |
| +6 | K181428 | Clyra Wound Irrigation Solution | Clyra Medical Technologies, Inc. | 2019 | 5 | — |
| +6 | K160095 | Simple Science Antimicrobial Wound & Skin Cleanser 2oz, Simple Science Antimicrobial… | Simple Science, LLC | 2016 | 3 | — |
| +7 | K262426 | Medical Diode Laser (S1Pro+, S1Pro K15, S1Pro N6, S1Pro N75) | Wuhan Pioon Technology Co., Ltd. | 2026 | 0 | — |
| +7 | K251757 | Puracyn® Plus Antimicrobial Irrigation Solution | Innovacyn, Inc. | 2026 | 0 | — |
| +7 | K251699 | The Botticelli (Model: Athena) | Bellamia Technologies, Inc. | 2025 | 0 | — |
| +7 | K250656 | Medical Diode Laser (Models: MZ-GK, MZ-K20, MZ-N75) | Wuhan Pioon Technology Co., Ltd. | 2025 | 0 | — |
| +7 | K242202 | LightWalker Laser System Family | Fotona D.O.O. | 2024 | 1 | — |
| +7 | K232885 | Dawn Diode Laser System | Shanghai Wonderful Opto-Electrics Tech.Co.,Ltd | 2024 | 0 | — |
| +7 | K213267 | Dynamis Pro Family | Fotona D.O.O. | 2022 | 2 | — |
| +7 | K220531 | Fox 810, Fox 980 | A.R.C Laser GmbH | 2022 | 0 | — |
| +7 | K202071 | SURGIPHOR Wound Irrigation System | Orthophor, LLC | 2020 | 4 | — |
| +7 | K181074 | Simple Science Antimicrobial Facial and Eyelid Cleanser | Simple Science, LLC | 2018 | 2 | — |
| +8 | K252723 | Dynamis Pro Family | Fotona D.O.O. | 2026 | 0 | — |
| +8 | K253309 | SOGA Lasers therapy system family of Aurora handpiece (Aurora-S); SOGA Lasers therapy… | Shenzhen Soga Technology Co., Ltd. | 2026 | 0 | — |
| +8 | K233399 | Microdacyn Wound Care Solution | Sonoma Pharmaceuticals, Inc. | 2024 | 1 | — |
| +8 | K223540 | AvalancheLase Family | Fotona D.O.O. | 2023 | 0 | — |
| +8 | K213616 | BD Surgiphor Antimicrobial Irrigation System | Becton, Dickinson and Company | 2022 | 3 | — |
| +9 | K261023 | Microdacyn Wound Irrigation Solution | Sonoma Pharmaceuticals, Inc. | 2026 | 0 | — |
| +9 | K221504 | BD Surgiphor™ Antimicrobial Irrigation System | Bd | 2022 | 2 | — |
| +10 | K253996 | BD Surgiphor™ Antimicrobial Irrigation System (910110) | Becton, Dickinson and Company (BD) | 2026 | 0 | — |
| +10 | K253445 | BD Surgiphor™ 1000 mL Antimicrobial Irrigation System (910120) | Bd | 2026 | 0 | — |