Devices descending from K021726
29 later devices reach Gebauer's Instant Ice through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K172203 | CryoDose TA OTC, Mist Spray, CryoDose TA OTC, Stream Spray | Nuance Medical, LLC | 2017 | 0 | — |
| +1 | K033720 | Ari Cold Spray | Ari | 2005 | 0 | — |
| +1 | K030281 | Cryotron 2 Cryotherapy Device | Cryonic Medical North America | 2003 | 14 | — |
| +1 | K031036 | Gebauer's Skin Refrigerant (Mist Spray), Model P/N 0386-0010-07, Gebauer's Skin… | Gebauer Co. | 2003 | 11 | 1 |
| +2 | K203661 | CRYO Arctic, CRYO Penguin | Cryoscience North America, Inc. | 2022 | 0 | — |
| +2 | K202782 | num Vapocoolant | 623 Medical, LLC | 2020 | 0 | — |
| +2 | K170810 | Cryofos | Cryofos Medical GmbH | 2017 | 13 | — |
| +2 | K032671 | Gebauer's Skin Refrigerant (Mist Stream), Gebauer's Skin Refrigerant (Stream Spray)… | Gebauer Co. | 2004 | 9 | 3 |
| +3 | K203481 | CryoVIVE | Recensmedical, Inc. | 2021 | 5 | — |
| +3 | K190161 | Ethyl Chloride Medium Jet Stream, Ethyl Chloride Fine Pinpoint spray, Ethyl Chloride… | Gebauer Company | 2019 | 0 | — |
| +3 | K182392 | Frozen C | B.M. Tech. Worldwide Co., Ltd. | 2018 | 6 | — |
| +3 | K172598 | Coventry Topical Anesthetic Mist Spray HAZMAT FREE, Coventry Topical Anesthetic Stream… | Itw Contamination Control Electronics | 2018 | 0 | — |
| +3 | K172028 | Gebauer’s Pain Ease Topical Anesthetic Skin Refrigerant (Mist Spray and Medium Spray) | Gebauer Company | 2017 | 4 | — |
| +3 | K162218 | Pain Freeze™, Medium Stream Spray, Model #2101; Pain Freeze™, Mist Spray, Model #2102 | Nuance Medical, LLC | 2016 | 3 | — |
| +4 | K261684 | FreezeSpray TA | Cryosurgery, Inc. | 2026 | 0 | — |
| +4 | K260870 | Gebauer's Pain Ease Topical Anesthetic Skin Refrigerant (Mist Spray and Medium Spray) | Gebauer Company | 2026 | 0 | — |
| +4 | K232674 | PainFreeze II | Nuance Medical, LLC | 2024 | 1 | — |
| +4 | K230599 | TargetCool™ | Recensmedical, Inc. | 2023 | 2 | — |
| +4 | K220674 | TargetCool | Recensmedical, Inc. | 2022 | 4 | — |
| +4 | K201260 | Dermal Cooling System | R2 Technologies, Inc. | 2020 | 3 | — |
| +4 | K193665 | Frozen N | Yozma Bmtech Co., Ltd. | 2020 | 1 | — |
| +4 | K193349 | Vapocoolshot Mist | Vapocoolshot, Inc. | 2020 | 1 | — |
| +5 | K253114 | TargetCool™ (RM-DT02W) | Recensmedical, Inc. | 2025 | 0 | — |
| +5 | K253348 | TargetCool-e | Recensmedical, Inc. | 2025 | 0 | — |
| +5 | K221234 | TargetCool | Recensmedical, Inc. | 2022 | 3 | — |
| +5 | K203006 | R2 Dermabrasion Tip (for Dermal Cooling System) | R2 Technologies, Inc. | 2021 | 2 | — |
| +5 | K201248 | Syringe Holder accessory | Vapocoolshot, Inc. | 2020 | 0 | — |
| +6 | K213294 | Dermal Cooling System | R2 Technologies, Inc. | 2022 | 1 | — |
| +7 | K253261 | Apollo Quattro (APQ-10M) | Weero Co., Ltd. | 2026 | 0 | — |