Modified MSQ Family of Lovely Light/Laser Systems

The Lovely System models (Aria and Harmony) are intended for use in aesthetic, cosmetic, and surgical applications requiring the ablation, vaporization, excision, incision, and photothermolysis (photocoagulation or coagulation) of soft tissue in the medical specialties of dermatology, general and plastic surgery, endoscopic/ laparoscopic general surgery, gastroenterology, gynecology, otorhinolaryngology (ENT), neurosurgery, oculoplastics, oral surgery, ophthalmology (skin around the eyes), orthopedics, pulmonary/thoracic surgery, and urology for surgical and aesthetic applications, as follows:

DERMATOLOGY AND PLASTIC SURGERY

Lovely I (Aria), Lovely II (Harmony) & Lovely III (TBD) Models:

The Advanced Fluorescence Technology (AFT) 420-950 rum wavelengths are indicated for:

• The treatment of moderate inflammatory acne vulgaris

• The treatment of benign pigmented epidermal lesions including dysehromia, hyperpigmentation, melasma, and ephelides (freckles)

• The treatment of cutaneous lesions including warts, scars and striae

• The treatment of benign cutaneous vascular lesions including port wine stains, hemangiomas, facial, truncal and leg telangiectasias, rosacea, erythema of rosacea, angiomas and spider angiomas, poikiloderma of Civatte, leg veins and venous malformations

• The removal of unwanted hair and to effect stable long-term or permanent hair reduction

Indicated for use on all skin types (Fitzpatrick I-IV), including tanned skin

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

The UV Light source (290-380nm) is indicated for:

• The treatment of leukoderma, including vitiligo (acquired leukoderma).

• The treatment of psoriasis, atopic dermatitis (eczema), and seborrheic dermatitis.

• Use on all skin types (Fitzpatrick I-VI), including tanned skin.

The 1064 nm Nd:YAG lasers (Long Pulsed and Q-Switched) are indicated for treatment and clearance of:

• Benign vascular lesions such as, but not limited to treatment of:

Port wine stains

Hemangiomas

Warts

Superficial and deep telangiectasias (venulectasias)

Reticular veins (0.1-4.0 mm diaj of the leg

Rosacea

Venus lake

Leg veins

Spider veins

Poikiloderma of Civatte

Angiomas

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

1064 nm Nd:YAG lasers (Long Pulsed and Q-Switched) - continued:

• Benign cutaneous lesions, such as:

Warts

Scars

Striae

Psoriasis

• Benign pigmented lesions such as, but not limited to:

Lentigos (age spots),

Solar lentigos (sun spots)

Caf: au lait macules

Seborrheic keratoses

Nevi and nevus of Ota

Chloasma

Verrucae

Skin tags

Keratoses

The removal of black, blue or green tattoos (significant reduction in the intensity of black and/or blue/black tattoos)

Plaques

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

1064 nm Nd:YAG lasers (Long Pulsed and Q-Switched) - continued:

• Pigmented lesions to reduce lesion size, for patients with lesions that would potentially benefit from aggressive treatment, and for patients with lesions that have not responded to other laser treatments.

• The non-ablative treatment of facial wrinkles, such as, but not limited to:

Periocular wrinkles

Perioral wrinkles

• Laser skin resurfacing procedures for the treatment of:

Acne scars

Wrinkles

• Removal of unwanted hair, for stable long term, or permanent, hair reduction through selective targeting of melanin in hair follicles

• Removal or lightening of unwanted hair (with and without adjuvant preparation)

Pseudofolliculitis barbae (PFB)

• Reduction of red pigmentation in hypertrophic and keloid scars where vascularity is an integral part of the scar

• Indicated for use on all skin types (Fitzpatrick [-IV), including tanned skin

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

The 532 nm Frequency-Doubled (FD) Nd:YAG lasers (Long Pulsed and Q-Switched) are indicated for:

• Incision, excision, ablation, vaporization of soft tissue

• Tattoo removal

Light blue

Yellow

Red

Green

• Vascular lesions

Hemanigomas (Port wine stains/ birthmarks, and cavernous, cherry, and spider hemangiormas)

Angiomas (cherry, spider)

Telangiectasia

Spider nevi

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

532 nm Frequency-Doubled (FD) Nd:YAG lasers (Long Pulsed & Q-Switched) - continued:

• Benign pigmented lesions

Caf6-au-lait (macules)

Lentigines (senile and solar)

Freckles (ephelides)

Chloasma

Nevi

Nevus spillus

Nevus of Ota

Becker's nevi

• Other pigmented cutaneous lesions

Verrucae

Skin tags

Keratoses

Plaques

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

1320 nm Nd:YAG laser is indicated for the treatment of:

• Fine lines and wrinkles

• Periorbital wrinkles

• Perioral wrinkles

• Back acne

• Atrophic acne scars

• Mild to moderate inflammatory acne vulgaris

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

2940 nm Er:YAG laser is indicated for use in soft tissue (skin, cutaneous tissue, subcutaneous tissue, striated and smooth tissue, muscle, cartilage meniscus, mucous membrane, lymph vessels and nodes, organs, and glands):

• Skin resurfacing

• Treatment of wrinkles

• Epidermal nevi

• Telangiectasia

• Spider veins

• Actinic chelitis

• Keloids

Verrucae

• Skin tags

• Anal tags

• Keratoses

• Scar revision (including acne scars)

• Debulking benign tunmors

• Debulking cysts

• Superficial skin lesions

• Diagnostic biopsies

• Decubitis ulcers

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

2940 nm Er:YAG laser - continued:

GENERAL SURGERY:

Surgical incision/excision, vaporization, ablation, and coagulation of soft tissue where skin incision, tissue dissection, excision of external tumors and lesions, complete or partial resection of internal organs, tumors and lesions, tissue ablation, and/or vessel coagulation may be indicated

GENITOURINARY:

Treatment of:

Lesions of the external genitalia, anus, penis, scrotum, and urethra (includes condyloma acuminate, giant perineal condyloma, and verrucous carcinoma), vulvar lesions, polyps, and familial polyps of the colon

GYNECOLOGY:

Treatment of:

• Cervical intraepithelial neoplasia (CIN), herpes simplex, endometrial adhesions, cysts, and condyloma

DERMATOLOGY AND PLASTIC SURGERY - continued

Lovely II (Harmony) & Lovely III (TBD) Models:

2940 nm Er:YAG laser - continued:

ORAL/MAXILLOFACIAL:

Treatment of:

• Benign oral tumors, oral and glossal lesions, and gingivectomy

OTORHINOLARYNGOLOGY/ HEAD AND NECK (ENT):

Treatment of:

Ear, nose and throat lesions, polyps, cysts, hyperkeratosis

Excision of carcinogenic tissue and oral leukoplakia

OPIHTHIALMOLOGY:

Treatment of:

• Soft tissue surrounding the eye and orbit

PODIATRY:

Treatment of:

Warts, plantar verrucae, large mosaic verrucae

• Matrixectomy