# K051950: Inscope Multi-Clip Applier, Models IN22321, IN23321

- Pathway: 510(k) (Traditional)
- Applicant: Ethicon Endo-Surgery, Inc.
- Decided: Oct 7, 2005 after 81 days
- Product code: MND (Ligator, Esophageal)
- Device class: 2
- Regulation: 21 CFR 876.4400
- Recalls of this device: none
- Data: FDA decisions to Oct 25, 2026; recalls to Oct 12, 2026

## Lineage
No predicates in its family tree.
8 later devices descend from it; 2 cite it directly.
0 of 9 devices in its family (counting itself) have a Class I recall.

## Predicates on the family tree (from the FDA summary)
- None. The FDA summary names its predicate without a number.
- (no number) Syntheon, LLC: Endoscopic Multi-Fire Clip Applier: named in the summary without a submission number
- (no number) Olympus Optical Co., Ltd.: Rotatable Clip Fixing Device HX-5/6-1: named in the summary without a submission number

## Most influential descendants
- K101428: Otsc (Over-the Scope-Clip) System Set (2010), 6 descendants of its own
- K120814: Padlock Clip-12 (2012), 2 descendants of its own
- K241858: BARS Set (100.60) (2024), 1 descendant of its own
- K180689: Padlock Clip defect closure device; Padlock Clip Pro-Select defect closure device (2018), 1 descendant of its own
- K251562: OTSCneo System Set (100.03n-14n, 100.27n-31n) (2025), 0 descendants of its own

## Indications for use
The InScope Multi-Clip Applier is indicated for use with an endoscope to place clips in the gastrointestinal (GI) tract for the purpose of: Endoscopic marking, Hemostasis for: Mucosal and submucosal defects < 3 cm Bleeding ulcers Arteries < 2 mm Polyps < 1.5 cm in diameter Diverticula in the colon Anchoring to affix jejunal feeding tubes to the wall of the small bowel, Closure of GI tract luminal perforations < 20 mm in patients where an alternative to surgery is required.

Source page: https://510kreport.com/device/K051950
Methodology: https://510kreport.com/methodology