# K171902: Nexstim Navigated Brain Therapy (NBT) System 2

- Pathway: 510(k) (Traditional)
- Applicant: Nexstim Plc
- Decided: Nov 10, 2017 after 137 days
- Product code: OBP (Transcranial Magnetic Stimulator)
- Device class: 2
- Regulation: 21 CFR 882.5805
- Recalls of this device: none
- Data: FDA decisions to Oct 25, 2026; recalls to Oct 12, 2026

## Lineage
Longest line of descent: 5 generations back to DEN070003 (2008). 5 ancestors in all.
13 later devices descend from it; 3 cite it directly.
0 of 19 devices in its family (counting itself) have a Class I recall.

## Predicates on the family tree (from the FDA summary)
- K143531: Rapid Therapy System, Magstim Company Limited (2015) Summary page 4.

## Most influential descendants
- K191422: Neural Navigator (2020), 8 descendants of its own
- K182700: Nexstim Navigated Brain Therapy (NBT) System 2 (2019), 3 descendants of its own
- K223577: Localite TMS Navigator TS (2023), 2 descendants of its own
- K220177: Magnus Neuromodulation System (MNS) with SAINT Technology, Model Number 1001K (2022), 2 descendants of its own
- K251927: Zeta Navigation System (ZNS131-US) (2025), 1 descendant of its own

## Indications for use
Nexstim Navigated Brain Therapy (NBT) System 2 is indicated for the treatment of Major Depressive Disorder in adult patients who have failed to achieve satisfactory improvement from prior antidepressant medication in the current episode.

Source page: https://510kreport.com/device/K171902
Methodology: https://510kreport.com/methodology