# K220419: Apapro Desensitizer

- Pathway: 510(k) (Traditional)
- Applicant: Sangi Co., Ltd.
- Decided: Feb 16, 2022 after 2 days
- Product code: LBH (Varnish, Cavity)
- Device class: 2
- Regulation: 21 CFR 872.3260
- Recalls of this device: none
- Data: FDA decisions to Oct 25, 2026; recalls to Oct 12, 2026

## Lineage
Longest line of descent: 3 generations back to K002989 (2000). 3 ancestors in all.
1 later device descends from it; 1 cites it directly.
0 of 5 devices in its family (counting itself) have a Class I recall.

## Predicates on the family tree (from the FDA summary)
- K040858: Oralief Therapy for Sensitive Teeth, Novamin Technology, Inc. (2004) Summary page 4.

## Most influential descendants
- K260830: APAPRO Desensitizer Homecare (Remineralizing Anti-sensitivity Toothpaste) (2026), 0 descendants of its own

## Indications for use
APAPRO Desensitizer is a fluoride-free paste that is indicated to provide relief from tooth hypersensitivity resulting from cold, heat, acids, sweets, or contact, through its action of dentin tubule occlusion.

Source page: https://510kreport.com/device/K220419
Methodology: https://510kreport.com/methodology