Devices descending from K222561
14 later devices reach Align through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K251459 | OneLIF™ Interbody Fusion System | Novapproach Spine, LLC | 2025 | 0 | — |
| +1 | K251335 | Tera Lumbar Interbody Fusion System (Various PNs) | Acuity Surgical Devices, LLC | 2025 | 1 | — |
| +1 | K242509 | HAnano InterFuse (R) Modular Interbody | Next Orthosurgical | 2024 | 0 | — |
| +1 | K241413 | sagAlign Lumbar Cage System (Various PNs) | Acuity Surgical Devices, LLC | 2024 | 0 | — |
| +1 | K232432 | E3D™-A Interbody System | Evolution Spine | 2024 | 8 | — |
| +2 | K254130 | C.A. Medical Interbody Fusion System | C.A. Medical, LLC | 2026 | 0 | — |
| +2 | K241846 | E3D™-C Interbody System | Evolution Spine | 2024 | 6 | — |
| +2 | K240368 | E3D™-A Interbody System | Evolution Spine | 2024 | 7 | — |
| +3 | K262094 | E3D™-C Interbody System | Evolution Spine | 2026 | 0 | — |
| +3 | K260036 | NeckTune™ 3D SA Cervical Cage | Medyssey Co, Ltd. | 2026 | 0 | — |
| +3 | K254105 | Hive™ Standalone Cervical System and Hive™ C Interbody System | NanoHive Medical, LLC | 2026 | 0 | — |
| +3 | K260038 | E3D™-C Interbody System | Evolution Spine | 2026 | 1 | — |
| +3 | K252894 | aprevo® cervical interbody system | Carlsmed, Inc. | 2026 | 1 | — |
| +4 | K260385 | aprevo® anterior and lateral lumbar interbody system; aprevo® posterior and… | Carlsmed, Inc. | 2026 | 0 | — |