Devices descending from K974328
65 later devices reach Advance Total Knee System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K121416 | GMK Sphere | Medacta International | 2012 | 20 | — |
| +1 | K052687 | Conformis, Inc. Total Knee Repair System | Conformis, Inc. | 2006 | 43 | — |
| +2 | K223548 | GMK Sphere & GMK SpheriKA Cementless | Medacta International S.A. | 2023 | 1 | — |
| +2 | K221850 | GMK 3D Metal Tibial Tray | Medacta International S.A. | 2022 | 1 | — |
| +2 | K211664 | GMK Sphere Revision | Medacta International S.A. | 2021 | 0 | — |
| +2 | K211004 | GMK Spherika Femurs and Fixed Tibial Trays Plus | Medacta International S.A. | 2021 | 4 | — |
| +2 | K202684 | GMK Total Knee System - TiNbN Coating | Medacta International S.A. | 2020 | 3 | — |
| +2 | K202022 | GMK-SPHERE Tibial inserts FLEX Tibial Insert CR and Resurfacing Patella made of E-CROSS… | Medacta International S.A. | 2020 | 1 | — |
| +2 | K173890 | GMK Sphere - Kinematic Alignment | Medacta International S.A. | 2018 | 6 | — |
| +2 | K181635 | GMK Sphere CR Tibial Inserts | Medacta International S.A. | 2018 | 2 | — |
| +2 | K162035 | GMK Sphere | Medacta International S.A. | 2017 | 10 | — |
| +2 | K142069 | GMK Extension | Medacta International | 2014 | 4 | — |
| +2 | K140826 | GMK Sphere Extension | Medacta International | 2014 | 17 | — |
| +2 | K133630 | GMK Short Stem | Medacta International | 2013 | 1 | — |
| +2 | K094050 | Itotal CR Knee Replacement System | Conformis, Inc. | 2010 | 41 | — |
| +2 | K080936 | Conformis Total Knee Repiar System (Itotal) Tibial Component: 6.0 MM Thickness | Conformis, Inc. | 2008 | 0 | — |
| +3 | K262057 | GMK Extension | Medacta International SA | 2026 | 0 | — |
| +3 | K253328 | GMK 3D Metal Tibial Tray Extension | Medacta International S.A. | 2026 | 0 | — |
| +3 | K243574 | Evolution® Total Knee Systems - Kinematic Alignment Instrumentation and Technique | Microport Orthopedics, Inc. | 2025 | 1 | — |
| +3 | K203755 | Shoulder System - TiNbN Coating | Medacta International S.A. | 2021 | 0 | — |
| +3 | K210010 | GMK Revision & Hinge Extension - TiNbN Coating | Medacta International S.A. | 2021 | 1 | — |
| +3 | K201343 | Triathlon Total KneeSystem | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2020 | 3 | — |
| +3 | K122870 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2013 | 33 | — |
| +3 | K122991 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 26 | — |
| +3 | K122033 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 26 | — |
| +3 | K120316 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 36 | — |
| +3 | K113378 | Conformis Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 36 | — |
| +3 | K120068 | Conformis Itotal CR Knee Replacement System (KRS) | Conformis, Inc. | 2012 | 36 | — |
| +3 | K112780 | Conformis Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2011 | 38 | — |
| +3 | K103117 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2011 | 40 | 1 |
| +4 | K253728 | EVOLUTION® AM BIOFOAM® Tibial System | Microport Orthopedics, Inc. | 2026 | 0 | — |
| +4 | K261898 | Triathlon® Knee System; Triathlon® Hinge Knee System; Scorpio® Total Knee System | Howmedica Osteonics Corp. dba Stryker Orthopaedics | 2026 | 0 | — |
| +4 | K161366 | ConfoMIS iTotal Cruciate Retaining (CR) Knee Replacement System (iTotal CR KRS) | Conformis, Inc. | 2016 | 18 | — |
| +4 | K140423 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2014 | 25 | 1 |
| +4 | K133560 | Itotal Cruciate Retaining Knee Replacment System | Conformis, Inc. | 2014 | 0 | — |
| +4 | K131467 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2013 | 30 | — |
| +4 | K131019 | Itotal Cruciate Retaining (C) Knee Replacement System | Conformis, Inc. | 2013 | 30 | — |
| +4 | K123692 | Pipeline Knee System | Pipeline Orthopedics | 2013 | 0 | — |
| +5 | K180906 | Conformis iTotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2018 | 17 | 4 |
| +5 | K142161 | Itotal Cruciate Retaining (CR) Knee Replacement System, Itotal Posterior Stabilized (PS)… | Conformis, Inc. | 2014 | 24 | 6 |
| +5 | K140833 | Itotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 26 | — |
| +5 | K133256 | Itotal Cruciate Retaining, Iuni Unicondylar Knee Replacement Systems, Iduo… | Conformis, Inc. | 2014 | 16 | 6 |
| +6 | K203421 | Triathlon AS-1 | Conformis, Inc. | 2021 | 0 | — |
| +6 | K193105 | iUni Unicondylar Knee Replacement System, iDuo Bicompartmental Knee Repair System… | Conformis, Inc. | 2020 | 15 | — |
| +6 | K190562 | iTotal Identity Cruciate Retaining Knee Replacement System | Conformis, Inc. | 2019 | 15 | — |
| +6 | K153721 | iTotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2016 | 0 | — |
| +6 | K160025 | iTotal Posterior Stabilized (PS) Knee Replacement System, iTotal Cruciate Retaining (CR)… | Conformis, Inc. | 2016 | 20 | 1 |
| +6 | K153217 | ConforMIS iTotal Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2016 | 18 | — |
| +6 | K152704 | iTotal Posterior Stabilized Knee Replacement System, iTotal Cruciate Retaining Knee… | Conformis, Inc. | 2015 | 23 | — |
| +6 | K142404 | iTotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 24 | 2 |
| +7 | K212411 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2021 | 9 | — |
| +7 | K210191 | Identity Imprint Knee Replacement System | Conformis, Inc. | 2021 | 10 | 1 |
| +7 | K203447 | iTotal Identity Cruciate Retaining (CR) Total Knee Replacement, iTotal Identity… | Conformis, Inc. | 2020 | 12 | — |
| +7 | K201023 | iTotal® Identity Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2020 | 14 | — |
| +7 | K161668 | ConforMIS iTotal (R) Posterior Stabilized (PS) Knee Replacement System (iTotal PS) | Conformis, Inc. | 2016 | 17 | 4 |
| +8 | K213389 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System and Identity Imprint… | Conformis, Inc. | 2021 | 8 | — |
| +8 | K210809 | iTotal® Identity™ Cruciate Retaining (CR) Knee Replacement System (KRS) | Conformis, Inc. | 2021 | 4 | 1 |
| +9 | K230846 | iTotal Identity Knee Replacement System; Identity Imprint Knee Replacement System | Conformis, Inc. | 2023 | 2 | — |
| +9 | K230844 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System (KRS) with Cruciate… | Conformis, Inc. | 2023 | 1 | — |
| +9 | K221059 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 7 | — |
| +10 | K243768 | iTotal® Identity™ Cruciate Retaining 3DP Porous Knee Replacement System | Restor3D, Inc. | 2025 | 0 | — |
| +10 | K232426 | Identity Imprint Porous Cruciate Retaining (CR) Knee Replacement System (KRS) with… | Conformis, Inc. | 2023 | 0 | — |
| +10 | K221404 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 6 | — |
| +11 | K223316 | Identity Imprint Porous Total Knee Replacement System, Identity Imprint Porous Cruciate… | Conformis, Inc. | 2023 | 2 | — |
| +11 | K231233 | Identity™ Imprint™ CR KRS and Identity™ Imprint™ PS KRS | Conformis, Inc. | 2023 | 0 | 1 |