Devices descending from K043420
87 later devices reach Osteofil, Optefil, Regenafil, Rti Allograft Paste through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K091912 | B-Genin and R-Genin | Berkeley Advanced Biomaterials, Inc. | 2010 | 1 | — |
| +1 | K061880 | Acceli DBM Family Products, 0.5CC, 1CC, 2.5CC, 5CC, 10CC, 15CC, 30CC | Isotis NV | 2007 | 5 | — |
| +1 | K062459 | Origen DBM with Bioactive Glass | Nanotherapeutics | 2007 | 56 | — |
| +1 | K060794 | Progenix DBM Putty and Paste | Medtronic Sofamor Danek | 2006 | 9 | — |
| +1 | K051047 | Colloss E Bone Void Filler | Ossacur AG | 2006 | 0 | — |
| +1 | K050806 | Optecure | Exactech, Inc. | 2006 | 3 | — |
| +1 | K053098 | Optium DBM Gel and Putty | Lifenet | 2005 | 39 | — |
| +1 | K050690 | Connexus | Isotis Orthobiologics, Inc. | 2005 | 6 | — |
| +2 | K242799 | PliaFX Flo | Lifenet Health | 2024 | 0 | — |
| +2 | K132868 | Carricell | Etex Corporation | 2015 | 3 | — |
| +2 | K121989 | Optecure Bone Void Filler (0.5 CC, 1CC, 2CC, 5CC, 10CC, and 20CC), Optecure + CCC Bone… | Exactech, Inc. | 2012 | 1 | — |
| +2 | K120279 | Nanofuse DBM | Nanotherapeutics | 2012 | 2 | — |
| +2 | K113791 | B-Genin, R-Genin | Berkeley Advanced Biomaterials, Inc. | 2012 | 0 | — |
| +2 | K110976 | Origen DBM with Bioactive Glass, Nanofuse DBM | Nanotherapeutics, Inc. | 2011 | 3 | 2 |
| +2 | K103742 | Accell EVO3 (Formerly Accell A2I) | Integra Life Sciences | 2011 | 0 | — |
| +2 | K091193 | Accell EVO3C | Isotis Orthobiologics, Inc. | 2009 | 2 | 1 |
| +2 | K082419 | Reoss Powder, Reoss Putty, Reoss Gel, Models R-1,RP-1, RG-1 | Intra-Lock International, Inc. | 2009 | 2 | — |
| +2 | K081817 | Accell TBM-R | Isotis Orthobiologics, Inc. | 2008 | 0 | — |
| +2 | K080462 | Progenix DBM Putty | Medtronic Sofamor Danek | 2008 | 2 | — |
| +2 | K080329 | Cap Plus, Equivabone, Cap/DBM | Etex Corp. | 2008 | 29 | — |
| +2 | K072265 | Progenix DMB Putty | Medtronic Sofamor Danek | 2008 | 4 | — |
| +2 | K063050 | Cap Plus | Etex Corp. | 2007 | 34 | — |
| +2 | K072184 | Vitoss Bioactive Foam Bone Graft Substitute | Orthovita, Inc. | 2007 | 51 | — |
| +2 | K061668 | Optecure +CCC | Exactech, Inc. | 2006 | 2 | — |
| +2 | K052098 | Connexus, .5CC, Model 023000-005 | Isotis Orthobiologics, Inc. | 2005 | 0 | — |
| +3 | K241555 | Moldable Bone Void Filler and Moldable Bone Void Filler + CCC | Rti Surgical, Inc. | 2025 | 0 | — |
| +3 | K212135 | Dry DBM- A Putty | Seaspine Corporation | 2021 | 1 | — |
| +3 | K163621 | Vitoss Bioactive (BA) Injectable | Orthovita, Inc. | 2017 | 2 | — |
| +3 | K153608 | Vitoss BiModal Bone Graft Substitute Foam Strip | Orthovita, Inc. | 2016 | 2 | — |
| +3 | K142104 | Nanofuse DBM | Nanotherapeutics, Inc. | 2015 | 1 | — |
| +3 | K101827 | Osteoscaf | Texas Innovative Medical Devices (Dba) Skeletal | 2011 | 1 | — |
| +3 | K102545 | FM-02 Bone Graft Substitute | Orthovita, Inc. | 2010 | 2 | — |
| +3 | K091729 | Alpha-BSM, Beta-BSM, Gamma-BSM, Equivabone | Etex Corp. | 2009 | 2 | — |
| +3 | K090855 | Equivabone Osteoinductive Bone Graft Substitute | Etex Corp. | 2009 | 25 | — |
| +3 | K090310 | Equivabone | Etex Corp. | 2009 | 28 | — |
| +3 | K082002 | Progenix Plus | Medtronic Sofamor Danek | 2008 | 0 | — |
| +3 | K082463 | Progenix | Medtronic Sofamor Danek | 2008 | 0 | — |
| +3 | K083033 | Vitoss Bone Graft Substitute, Bone Graft Substitute Filled Canister, Foam & Bioactive… | Orthovita, Inc. | 2008 | 47 | — |
| +3 | K081950 | Progenix Plus | Medtronic Sofamor Danek, Inc. | 2008 | 1 | — |
| +3 | K081439 | Vitoss Bioactive Foam Pack Bone Graft Substitute | Orthovita, Inc. | 2008 | 50 | — |
| +4 | K243949 | OsteoFlo HydroFiber | SurGenTec, LLC | 2025 | 0 | — |
| +4 | K242797 | OsteoFlo HydroFiber | SurGenTec, LLC | 2024 | 1 | — |
| +4 | K240450 | Citrepore™ | Acuitive Technologies, Inc. | 2024 | 0 | — |
| +4 | K242280 | Vitoss® BiModal Bioactive Bone Graft Substitute Foam Strip, Vitoss® BiModal Bioactive… | Stryker Spine | 2024 | 1 | — |
| +4 | K231030 | Cove Putty, OsteoCove Putty | SeaSpine Orthopedics Corporation | 2023 | 0 | — |
| +4 | K213260 | CMFlexTM | Dimension Inx Corp. | 2022 | 0 | — |
| +4 | K203218 | CaP Spheres Pellet Pack | Zimmer Biomet Spine, Inc. | 2021 | 0 | — |
| +4 | K182074 | Mineral Collagen Composite Bioactive Moldable | Collagen Matrix, Inc. | 2019 | 3 | — |
| +4 | K161996 | 0.5cc NanoFUSE, 1.0cc NanoFUSE, 2cc NanoFUSE, 5cc NanoFUSE, 10cc NanoFUSE | Amend Surgical, Inc. | 2017 | 0 | — |
| +4 | K141207 | Novabone Bioactive Strip | Novabone Products, LLC | 2014 | 0 | — |
| +4 | K132050 | NB3D Bone Void Filler | Pioneer Surgical Technology, Inc. | 2014 | 0 | 1 |
| +4 | K130703 | Vivorte BVF | Vivorte, Inc. | 2013 | 1 | 1 |
| +4 | K113049 | Socket Graft | Steiner Laboratories | 2012 | 0 | — |
| +4 | K111944 | NB3D Bone Void Filler | Pioneer Surgical Technology, Inc. | 2011 | 1 | — |
| +4 | K103173 | Vitoss BA Bimodal Bioactive Bone Graft Substitute | Orthovita, Inc. | 2011 | 17 | — |
| +4 | K100883 | Carrigen | Etex Corp. | 2010 | 0 | — |
| +4 | K102812 | Gamma-BSM; Beta-BSM; Equivabone | Etex Corporation | 2010 | 0 | — |
| +4 | K101557 | Gamma-BSM, Beta-BSM, Equivabone, Carigen | Etex Corp. | 2010 | 10 | — |
| +4 | K093447 | Carrigen | Etex Corp. | 2010 | 21 | — |
| +4 | K091607 | Alpha-BSM, Beta-BSM, Gamma-BSM, Equivabone | Etex Corp. | 2009 | 22 | — |
| +4 | K090387 | Kainos+ | Signus Medizintechnik GmbH | 2009 | 0 | — |
| +5 | K261008 | Vitoss® BiModal Bioactive Bone Graft Substitute Foam Strip; Vitoss® BiModal Bioactive… | Stryker Spine | 2026 | 0 | — |
| +5 | K243609 | EquivaBone Osteoinductive Bone Graft Substitute (EquivaBone ) | Etex Corporation | 2024 | 0 | — |
| +5 | K231942 | Mineral Collagen Composite Bioactive Extra Moldable | Collagen Matrix, Inc. | 2023 | 1 | — |
| +5 | K221735 | Mineral Collagen Composite Bioactive Moldable | Collagen Matrix, Inc. | 2022 | 2 | — |
| +5 | K190814 | AccuFill Bone Substitute Material | Zimmer Knee Creations | 2019 | 0 | — |
| +5 | K182107 | CarriGen PF | Etex Corporation | 2018 | 1 | — |
| +5 | K171284 | FIBERGRAFT BG Matrix Bone Graft Substitute | Prosidyan, Inc. | 2017 | 1 | — |
| +5 | K143547 | Vivorte Trabexus EB | Vivorte, Inc. | 2015 | 0 | 1 |
| +5 | K133678 | Confirm Bioactive | Globus Medical, Inc. | 2014 | 0 | — |
| +5 | K130392 | Kinex Bioactive | Globus Medical, Inc. | 2013 | 8 | — |
| +5 | K103799 | Inqu Paste Mix Plus | Isto Technologies, Inc. | 2011 | 9 | — |
| +5 | K102528 | N-Force Fixation System | Innovision, Inc. | 2011 | 5 | — |
| +6 | K240424 | Mineral Collagen Composite Bioactive Moldable Bone Graft Matrix | Collagen Matrix, Inc. | 2024 | 0 | — |
| +6 | K182670 | FIBERGRAFT AERIDYAN Matrix Bone Graft Substitute | Prosidyan, Inc. | 2018 | 0 | — |
| +6 | K173008 | SCS 17-01 | Anika Therapeutics, Inc. | 2017 | 4 | — |
| +6 | K160791 | AmorChem Titanium Porous Fixation Device | Amorchem Holdings, Inc. | 2016 | 0 | — |
| +6 | K151146 | N-Force Fixation System | Innovision, Inc. | 2015 | 1 | — |
| +6 | K142776 | Flow-Screw | Flow-Fx, LLC | 2015 | 1 | — |
| +6 | K132244 | N-Force Fixation System | Innovision, Inc. | 2014 | 3 | — |
| +6 | K130977 | Signify Bioactive | Globus Medical, Inc. | 2013 | 1 | — |
| +7 | K223915 | Tactoset | Anika Therapeutics, Inc. | 2023 | 1 | — |
| +7 | K221737 | InstaFill Graft Delivery System, SIGNIFY Bioactive | Globus Medical, Inc. | 2022 | 0 | — |
| +7 | K212083 | Tactoset Injectable Bone Substitute | Anika Therapeutics, Inc. | 2021 | 2 | — |
| +7 | K190956 | SCS 17-01 | Anika Therapeutics, Inc. | 2020 | 3 | — |
| +7 | K173556 | Injection Screw | Biedermann Medtech, Inc. | 2018 | 0 | — |
| +8 | K231968 | Tactoset® Injectable Bone Substitute | Anika Therapeutics, Inc. | 2023 | 0 | — |