Devices descending from K100048
114 later devices reach E1 Antioxidant Infused Technology through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K120038 | A200 Knee System | Renovis Surgical Technologies, LLC | 2013 | 2 | — |
| +1 | K122529 | Zimmer Unicompartmental Knee System Vivacit-E Articular Surface | Zimmer, Inc. | 2012 | 15 | — |
| +1 | K121771 | Zimmer Persona the Personalized Knee System | Zimmer, Inc. | 2012 | 59 | 2 |
| +1 | K120370 | Vivacit-E Vitamin E Highly Crosslinked Polyethylene Liners | Zimmer, Inc. | 2012 | 88 | — |
| +1 | K101336 | E1 Avantage Head | Biomet Manufacturing Corp | 2011 | 24 | 1 |
| +2 | K243295 | Initia Knee System | Kyocera Medical Technologies, Inc. | 2025 | 0 | — |
| +2 | K230653 | Smith & Nephew, Inc. ANTHEM Total Knee System, Genesis Uni Knee System, JOURNEY BCS and… | Smith & Nephew, Inc. | 2023 | 3 | 1 |
| +2 | K222566 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2022 | 2 | — |
| +2 | K200823 | Zimmer, Inc. Hip Joint Prostheses MR Labeling I | Zimmer, Inc. | 2020 | 1 | 1 |
| +2 | K190656 | Dual Mobility - Longevity and Vivacit-E Polyethylene Hip Bearings | Zimmer, Inc. | 2019 | 1 | 3 |
| +2 | K190660 | G7 Acetabular System Longevity Highly Crosslinked Polyethylene, G7 Acetabular System… | Zimmer, Inc. | 2019 | 4 | — |
| +2 | K190122 | Renovis A200 PS Knee System as part of the Renovis A200 Knee System | Renovis Surgical Technologies | 2019 | 1 | — |
| +2 | K190068 | Vanguard XP Knee System | Zimmer, Inc. | 2019 | 0 | — |
| +2 | K183583 | Vanguard Complete Knee System | Zimmer, Inc. | 2019 | 1 | — |
| +2 | K181947 | Persona Revision Knee System | Zimmer, Inc. | 2018 | 4 | 1 |
| +2 | K173380 | b-ONE® Total Hip System | B-One Ortho, Corp. | 2018 | 0 | — |
| +2 | K172524 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2018 | 15 | — |
| +2 | K173417 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2018 | 9 | — |
| +2 | K161592 | Persona Partial Knee System | Biomet, Inc. | 2016 | 5 | 2 |
| +2 | K160738 | ZUK Select Knee System | Smith & Nephew, Inc. | 2016 | 8 | — |
| +2 | K161190 | G7 Dual Mobility System, Active Articulation System | Biomet, Inc. | 2016 | 7 | — |
| +2 | K150090 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2015 | 17 | — |
| +2 | K150522 | G7 Dual Mobility System | Biomet, Inc. | 2015 | 21 | 1 |
| +2 | K141635 | Arthrex Ibalance Tka System | Arthrex, Inc. | 2014 | 15 | — |
| +2 | K140701 | Novohip Bipolar Head/Novohip Vitamin E Liner/ Bone Screws/ Hole Plug | Novosource, Inc. | 2014 | 2 | — |
| +2 | K123459 | Zimmer Persona TM Personalized Knee System | Zimmer, Inc. | 2013 | 9 | 10 |
| +2 | K111981 | Tregor Dual Mobility Acetabular System | Aston Medical | 2012 | 0 | — |
| +2 | K110555 | Arcomxl Active Articulation | Biomet Manufacturing Corp | 2011 | 22 | 2 |
| +3 | K261453 | G7® Acetabular System | Zimmer Biomet | 2026 | 0 | — |
| +3 | K261462 | LANDMARK Total Knee System | Smith & Nephew, Inc. | 2026 | 0 | — |
| +3 | K253948 | Momentum Acetabular Cup System | United Orthopedic Corporation | 2026 | 0 | — |
| +3 | K253961 | SK Knee System | Just Medical Devices (Tianjin) Co., Ltd. | 2026 | 0 | — |
| +3 | K252067 | Velora Acetabular System | Restor3D, Inc. | 2025 | 0 | — |
| +3 | K251834 | Persona Partial Knee | Zimmer Biomet | 2025 | 0 | — |
| +3 | K243456 | ONVOY™ Acetabular System | Globus Medical, Inc. | 2025 | 0 | — |
| +3 | K250834 | Zimmer Biomet Ceramic Heads (22.2mm diameter) | Zimmer Biomet | 2025 | 0 | — |
| +3 | K243724 | Persona® Revision Knee System (Persona Revision SoluTion™ Femoral Components) | Zimmer, Inc. | 2025 | 0 | — |
| +3 | K243574 | Evolution® Total Knee Systems - Kinematic Alignment Instrumentation and Technique | Microport Orthopedics, Inc. | 2025 | 1 | — |
| +3 | K243293 | Zimmer® Persona® Personalized Knee System | Zimmer Biomet | 2024 | 1 | — |
| +3 | K241260 | ACTIFY™ Unicondylar Knee System | Globus Medical, Inc. | 2024 | 0 | — |
| +3 | K242412 | Agility Symmetric™ Total Knee System | Medisurge, LLC | 2024 | 0 | — |
| +3 | K242711 | JOURNEY II Unicompartmental Knee System (JOURNEY II UK) | Smith & Nephew, Inc. | 2024 | 0 | — |
| +3 | K241570 | Unity Total Knee System | Corin U.S.A. Limited | 2024 | 0 | — |
| +3 | K233724 | 28mm/38D MDM X3 Insert for MDM Liner | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2024 | 0 | — |
| +3 | K223316 | Identity Imprint Porous Total Knee Replacement System, Identity Imprint Porous Cruciate… | Conformis, Inc. | 2023 | 2 | — |
| +3 | K230321 | Persona™ Personalized Knee System | Zimmer, Inc. | 2023 | 0 | — |
| +3 | K221479 | Persona Personalized Knee System | Zimmer, Inc. | 2022 | 8 | — |
| +3 | K212870 | TLC Unicompartmental Knee System | Signature Orthopaedics Pty, Ltd. | 2022 | 2 | — |
| +3 | K213381 | Physica system | Lima Corporate S.P.A. | 2021 | 0 | 1 |
| +3 | K200011 | E-CLASS® DUAL MOBILITY INSERTS and DYNASTY® DUAL MOBILITY LINERS | Microport Orthopedics, Inc. | 2021 | 1 | — |
| +3 | K211609 | ATTUNE Medial Stabilized (MS) Fixed Bearing (FB) Insert | Depuy Ireland UC | 2021 | 2 | — |
| +3 | K200607 | LINK MobileLink® Acetabular Cup System - Dual Mobility Liners, and Shell/Insert Adapters | Waldemar Link GmbH & Co. KG | 2021 | 1 | 1 |
| +3 | K210829 | Persona Revision Knee System Femoral Metaphyseal Cones | Zimmer, Inc. | 2021 | 0 | — |
| +3 | K203557 | EMPOWR Dual Mobility Metal Liner, EMPOWR Dual Mobility Poly Bearing | Encore Medical L.P. | 2021 | 0 | 2 |
| +3 | K201343 | Triathlon Total KneeSystem | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2020 | 3 | — |
| +3 | K200151 | Persona Partial Knee Tibial Cut Guide 5 Deg Left Medial Right Lateral, Persona Partial… | Zimmer, Inc. | 2020 | 0 | — |
| +3 | K193284 | Physica LMC Knee System | Lima Corporate S.P.A. | 2020 | 6 | — |
| +3 | K193223 | Persona Personalized Knee System | Zimmer, Inc. | 2020 | 3 | — |
| +3 | K191625 | Persona Revision Knee System | Zimmer, Inc. | 2019 | 1 | 1 |
| +3 | K191211 | JOURNEY II Unicompartmental Knee System | Smith & Nephew, Inc. | 2019 | 1 | — |
| +3 | K181491 | Delta Dual Mobility System | Lima Corporate S.P.A. | 2019 | 0 | — |
| +3 | K190085 | Journey II Unicompartmental Knee System | Smith & Nephew, Inc. | 2019 | 7 | 3 |
| +3 | K181366 | REDAPT Porous Acetabular Shell | Smith & Nephew, Inc. | 2018 | 1 | — |
| +3 | K173890 | GMK Sphere - Kinematic Alignment | Medacta International S.A. | 2018 | 6 | — |
| +3 | K170359 | Trinity™ Dual Mobility System | Corin U.S.A. Limited | 2017 | 10 | 1 |
| +3 | K151424 | The Progressive Orthopaedic Total Hip System | The Progressive Orthopaedic Company, LLC | 2016 | 1 | — |
| +3 | K151256 | Arthrex BioSync® Bone Wedge | Arthex, Inc. | 2015 | 10 | 6 |
| +4 | K253728 | EVOLUTION® AM BIOFOAM® Tibial System | Microport Orthopedics, Inc. | 2026 | 0 | — |
| +4 | K261898 | Triathlon® Knee System; Triathlon® Hinge Knee System; Scorpio® Total Knee System | Howmedica Osteonics Corp. dba Stryker Orthopaedics | 2026 | 0 | — |
| +4 | K261609 | Freedom Partial Knee System | Maxx Orthopedics, Inc. | 2026 | 0 | — |
| +4 | K262251 | ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert) | Globus Medical, Inc. | 2026 | 0 | — |
| +4 | K251840 | Zimmer® Persona® Personalized Knee System | Zimmer, Inc. | 2026 | 0 | — |
| +4 | K253189 | Persona the Personalized Knee System (Persona Porous Plasma Spray PPS Femurs) | Zimmer, Inc. | 2026 | 0 | — |
| +4 | K253637 | Triathlon® Total Knee System - Triathlon® X3® Medial Stabilized Tibial Bearing Insert | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2026 | 0 | — |
| +4 | K251771 | Cambridge Partial Knee | Signature Orthopaedics Pty, Ltd. | 2025 | 0 | — |
| +4 | K253197 | ATTUNE™ Total Knee System; ATTUNE™ Revision Sleeve LPS™ Femoral Adaptors | Depuy Ireland UC | 2025 | 0 | — |
| +4 | K242744 | Trinity EVO Acetabular Shell | Corin U.S.A. Limited | 2025 | 0 | — |
| +4 | K243768 | iTotal® Identity™ Cruciate Retaining 3DP Porous Knee Replacement System | Restor3D, Inc. | 2025 | 0 | — |
| +4 | K240461 | OsteoSinter® EVANS and COTTON wedges and related accessories | Ames Medical Prosthetic Solutions, S.A.U. | 2024 | 2 | — |
| +4 | K242543 | Persona the Personalized Knee System (Persona Ti-Nidium PPS Femurs) | Zimmer, Inc. | 2024 | 0 | — |
| +4 | K240299 | Persona the Personalized Knee System (Persona OsseoTi 3-Peg Patella) | Zimmer, Inc. | 2024 | 3 | — |
| +4 | K240046 | Ethylene Oxide Sterilization Supplier Change for MPO Hips | Microport Orthopedics | 2024 | 0 | — |
| +4 | K232114 | TRIBRID® Unicompartmental Knee System | Kyocera Medical Technologies, Inc. | 2024 | 0 | — |
| +4 | K230078 | TRAX® CR Total Knee System | Amplitude | 2023 | 0 | — |
| +4 | K232426 | Identity Imprint Porous Cruciate Retaining (CR) Knee Replacement System (KRS) with… | Conformis, Inc. | 2023 | 0 | — |
| +4 | K222066 | LINK MobileLink Acetabular Cup System | Waldemar Link GmbH & Co. KG | 2023 | 0 | — |
| +4 | K230471 | LinkSymphoKnee – Fixed Bearing Ultracongruent (FB UC) Articulating Surface | Waldemar Link GmbH & Co. KG | 2023 | 0 | — |
| +4 | K222653 | JOURNEY II UK™ and ENGAGE™ Cementless Partial Knee System | Smith+Nephew, Inc. | 2022 | 0 | — |
| +4 | K221850 | GMK 3D Metal Tibial Tray | Medacta International S.A. | 2022 | 1 | — |
| +4 | K201657 | Corin Ltd. Hip Products: Trinity™ Acetabular System, Trinity™ PLUS Acetabular Shell… | Corin, Ltd. | 2021 | 2 | — |
| +4 | K211938 | Physica LMC Knee System | Limacorporate | 2021 | 0 | — |
| +4 | K210551 | Persona Revision Knee System | Zimmer, Inc. | 2021 | 0 | 1 |
| +4 | K201084 | Physica system | Lima Corporate S.P.A. | 2020 | 5 | — |
| +4 | K193414 | Trigon HA Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2020 | 6 | — |
| +4 | K191831 | MobiliT Cup | Corin U.S.A. Limited | 2020 | 3 | — |
| +4 | K192645 | Trigon™ Ti Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2019 | 7 | — |
| +4 | K192450 | Precision Casting Solutions Total Hip System | Precision Casting Solution, LLC | 2019 | 0 | — |
| +4 | K190890 | Exactech Alteon Modular Dual Mobility (MDM) System | Exactech, Inc. | 2019 | 0 | — |
| +4 | K190535 | BiMobile Dual Mobility System - E-Dur Inserts | Waldemar Link GmbH & Co. KG | 2019 | 3 | 1 |
| +5 | K253328 | GMK 3D Metal Tibial Tray Extension | Medacta International S.A. | 2026 | 0 | — |