Devices descending from K121443
37 later devices reach Journey II CR Knee System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K261462 | LANDMARK Total Knee System | Smith & Nephew, Inc. | 2026 | 0 | — |
| +1 | K230653 | Smith & Nephew, Inc. ANTHEM Total Knee System, Genesis Uni Knee System, JOURNEY BCS and… | Smith & Nephew, Inc. | 2023 | 3 | 1 |
| +1 | K211671 | Journey II Mid-Level Tibial Inserts | Smith & Nephew, Inc. | 2021 | 1 | — |
| +1 | K200407 | LEGION Inserts with JRNY Lock | Smith & Nephew, Inc. | 2020 | 2 | — |
| +1 | K141934 | Physica KR Knee System | Lima Corporate S.P.A. | 2015 | 18 | — |
| +1 | K141471 | Journey II XR Knee System | Smith & Nephew, Inc. | 2014 | 12 | — |
| +1 | K123692 | Pipeline Knee System | Pipeline Orthopedics | 2013 | 0 | — |
| +2 | K250677 | LEGION Total Knee System | Smith & Nephew, Inc. | 2025 | 0 | — |
| +2 | K241260 | ACTIFY™ Unicondylar Knee System | Globus Medical, Inc. | 2024 | 0 | — |
| +2 | K242711 | JOURNEY II Unicompartmental Knee System (JOURNEY II UK) | Smith & Nephew, Inc. | 2024 | 0 | — |
| +2 | K220896 | Legion Inserts with JRNY Lock | Smith & Nephew, Inc. | 2022 | 1 | — |
| +2 | K201084 | Physica system | Lima Corporate S.P.A. | 2020 | 5 | — |
| +2 | K193284 | Physica LMC Knee System | Lima Corporate S.P.A. | 2020 | 6 | — |
| +2 | K190911 | Physica KR Liner and SMR Reverse Humeral Liner | Limacorporate | 2019 | 8 | — |
| +2 | K173331 | JOURNEY II XR Knee Instruments | Smith & Nephew, Inc. | 2017 | 1 | 4 |
| +2 | K152008 | Physica PS Knee System | Lima Corporate S.P.A. | 2015 | 7 | — |
| +2 | K152315 | JOURNEY II Uni Tibial Base and Insert | Smith & Nephew, Inc. | 2015 | 8 | — |
| +2 | K152726 | JOURNEY II XR Knee System | Smith & Nephew, Inc. | 2015 | 4 | — |
| +2 | K151266 | Physica CR Knee System | Lima Corporate S.P.A. | 2015 | 8 | — |
| +3 | K250980 | Physica System (Physica CR Porous Femoral components) | Lima Corporate S.P.A. | 2025 | 0 | — |
| +3 | K220792 | SMR Reverse Liner | Lima Corporate S.P.A. | 2022 | 7 | — |
| +3 | K213381 | Physica system | Lima Corporate S.P.A. | 2021 | 0 | 1 |
| +3 | K211938 | Physica LMC Knee System | Limacorporate | 2021 | 0 | — |
| +3 | K210554 | Physica system | Lima Corporate S.P.A. | 2021 | 2 | — |
| +3 | K200227 | Journey II XR Knee Instrument | Smith & Nephew, Inc. | 2020 | 0 | — |
| +3 | K190085 | Journey II Unicompartmental Knee System | Smith & Nephew, Inc. | 2019 | 7 | 3 |
| +4 | K251184 | AltiVate Reverse Shoulder System; RSP Shoulder System; SMR Shoulder System; PRIMA… | Encore Medical L.P. | 2025 | 0 | — |
| +4 | K243615 | Physica Porous Femoral Components | Lima Corporate S.P.A. | 2024 | 1 | — |
| +4 | K232114 | TRIBRID® Unicompartmental Knee System | Kyocera Medical Technologies, Inc. | 2024 | 0 | — |
| +4 | K223876 | SMR Shoulder System | Lima Corporate S.P.A. | 2023 | 3 | — |
| +4 | K222653 | JOURNEY II UK™ and ENGAGE™ Cementless Partial Knee System | Smith+Nephew, Inc. | 2022 | 0 | — |
| +4 | K222427 | PRIMA TT Glenoid | Lima Corporate S.P.A. | 2022 | 2 | 3 |
| +4 | K191211 | JOURNEY II Unicompartmental Knee System | Smith & Nephew, Inc. | 2019 | 1 | — |
| +5 | K243826 | SMR Reverse HP Shoulder System | Lima Corporate S.P.A. | 2025 | 1 | — |
| +5 | K233712 | PRIMA Humeral System; PRIMA TT Glenoid | Lima Corporate S.P.A. | 2024 | 1 | — |
| +5 | K231099 | SMR Hybrid Glenoid System | Lima Corporate S.P.A. | 2023 | 0 | — |
| +6 | K252352 | SMR Shoulder System; PRIMA Glenoid System; PRIMA Humeral System | Lima Corporate S.P.A. | 2026 | 0 | — |