Devices descending from K936159
161 later devices reach Natural-Knee II System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +4 | K210961 | U2 Total Knee System, XPE Tibial Insert, PS PLUS | United Orthopedic Corporation | 2021 | 0 | — |
| +4 | K203447 | iTotal Identity Cruciate Retaining (CR) Total Knee Replacement, iTotal Identity… | Conformis, Inc. | 2020 | 12 | — |
| +4 | K201960 | SpaceFlex Knee - 80mm Size | G21, S.R.L. | 2020 | 0 | — |
| +4 | K201023 | iTotal® Identity Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2020 | 14 | — |
| +4 | K193284 | Physica LMC Knee System | Lima Corporate S.P.A. | 2020 | 6 | — |
| +4 | K191016 | COPAL exchange G Hip and Knee Spacers | Heraeus Medical GmbH | 2019 | 1 | — |
| +4 | K171365 | Arthrex Knee Systems | Arthrex, Inc. | 2017 | 0 | — |
| +4 | K163332 | Apex Revision Knee System | Omnilife Science | 2017 | 3 | — |
| +4 | K153721 | iTotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2016 | 0 | — |
| +4 | K160025 | iTotal Posterior Stabilized (PS) Knee Replacement System, iTotal Cruciate Retaining (CR)… | Conformis, Inc. | 2016 | 20 | 1 |
| +4 | K153586 | Arthrex iBalance TKA System | Arthrex, Inc. | 2016 | 1 | — |
| +4 | K153217 | ConforMIS iTotal Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2016 | 18 | — |
| +4 | K152704 | iTotal Posterior Stabilized Knee Replacement System, iTotal Cruciate Retaining Knee… | Conformis, Inc. | 2015 | 23 | — |
| +4 | K151256 | Arthrex BioSync® Bone Wedge | Arthex, Inc. | 2015 | 10 | 6 |
| +4 | K112470 | 2GC Hip/Knee Modular Spacer | Mandell Horwitz Consultants, LLC | 2012 | 16 | — |
| +5 | K260063 | GSPE Spacer | The General Hospital Corporation, d/b/a Massachusetts | 2026 | 0 | — |
| +5 | K262251 | ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert) | Globus Medical, Inc. | 2026 | 0 | — |
| +5 | K253328 | GMK 3D Metal Tibial Tray Extension | Medacta International S.A. | 2026 | 0 | — |
| +5 | K253675 | OsteoRemedies Hip Spacer System | Osteoremedies, LLC | 2025 | 1 | — |
| +5 | K253197 | ATTUNE™ Total Knee System; ATTUNE™ Revision Sleeve LPS™ Femoral Adaptors | Depuy Ireland UC | 2025 | 0 | — |
| +5 | K243768 | iTotal® Identity™ Cruciate Retaining 3DP Porous Knee Replacement System | Restor3D, Inc. | 2025 | 0 | — |
| +5 | K240461 | OsteoSinter® EVANS and COTTON wedges and related accessories | Ames Medical Prosthetic Solutions, S.A.U. | 2024 | 2 | — |
| +5 | K232426 | Identity Imprint Porous Cruciate Retaining (CR) Knee Replacement System (KRS) with… | Conformis, Inc. | 2023 | 0 | — |
| +5 | K220492 | COPAL exchange G hip spacer | Heraeus Medical GmbH | 2022 | 0 | — |
| +5 | K213389 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System and Identity Imprint… | Conformis, Inc. | 2021 | 8 | — |
| +5 | K211938 | Physica LMC Knee System | Limacorporate | 2021 | 0 | — |
| +5 | K210809 | iTotal® Identity™ Cruciate Retaining (CR) Knee Replacement System (KRS) | Conformis, Inc. | 2021 | 4 | 1 |
| +5 | K203421 | Triathlon AS-1 | Conformis, Inc. | 2021 | 0 | — |
| +5 | K201084 | Physica system | Lima Corporate S.P.A. | 2020 | 5 | — |
| +5 | K193414 | Trigon HA Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2020 | 6 | — |
| +5 | K192995 | OsteoRemedies Hip Spacer System | Osteoremedies, LLC | 2020 | 2 | — |
| +5 | K192645 | Trigon™ Ti Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2019 | 7 | — |
| +5 | K191765 | OMNI TiN Coated Apex Knee™ System | Omni Life Science, Inc. | 2019 | 2 | — |
| +5 | K183017 | Remedy Femoral Component 84mm, Remedy Stemmed Knee Spacer | Osteoremedies, LLC | 2019 | 5 | — |
| +5 | K173967 | Remedy Acetabular Cup | Osteoremedies, LLC | 2018 | 5 | — |
| +5 | K161668 | ConforMIS iTotal (R) Posterior Stabilized (PS) Knee Replacement System (iTotal PS) | Conformis, Inc. | 2016 | 17 | 4 |
| +5 | K161366 | ConfoMIS iTotal Cruciate Retaining (CR) Knee Replacement System (iTotal CR KRS) | Conformis, Inc. | 2016 | 18 | — |
| +6 | K262290 | REMEDY POLY+PLUS SNAP FIT Acetabular Cup | Osteoremedies, LLC | 2026 | 0 | — |
| +6 | K252044 | Triathlon® Total Knee System - Triathlon® Gold Femoral Components | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2025 | 0 | — |
| +6 | K252254 | Osteotomy Wedge System | Sinaptic Surgical | 2025 | 0 | — |
| +6 | K251791 | Auxano® Wedge Fixation System | Auxano Medical, LLC | 2025 | 0 | — |
| +6 | K243231 | Trigon PEEK HA Wedges | Nvision Biomedical Technologies | 2024 | 1 | — |
| +6 | K242377 | REMEDY Stemmed Knee Spacer System with All-Poly Tibial Component | Osteoremedies, LLC | 2024 | 0 | — |
| +6 | K240683 | Rx Knee System | Signature Orthopaedics Pty, Ltd. | 2024 | 2 | — |
| +6 | K234116 | Trigon Trigon HA Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies | 2024 | 0 | — |
| +6 | K230846 | iTotal Identity Knee Replacement System; Identity Imprint Knee Replacement System | Conformis, Inc. | 2023 | 2 | — |
| +6 | K230844 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System (KRS) with Cruciate… | Conformis, Inc. | 2023 | 1 | — |
| +6 | K223650 | REMEDY Stemmed Knee Spacer | Osteoremedies, LLC | 2023 | 1 | — |
| +6 | K223226 | Trigon™ HA Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2022 | 0 | — |
| +6 | K221059 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 7 | — |
| +6 | K220197 | Trigon HA Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2022 | 4 | — |
| +6 | K210554 | Physica system | Lima Corporate S.P.A. | 2021 | 2 | — |
| +6 | K203445 | Trigon HA Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2020 | 5 | — |
| +6 | K193105 | iUni Unicondylar Knee Replacement System, iDuo Bicompartmental Knee Repair System… | Conformis, Inc. | 2020 | 15 | — |
| +6 | K191981 | REMEDY Acetabular Cup | Osteoremedies, LLC | 2019 | 4 | — |
| +6 | K180906 | Conformis iTotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2018 | 17 | 4 |
| +7 | K250980 | Physica System (Physica CR Porous Femoral components) | Lima Corporate S.P.A. | 2025 | 0 | — |
| +7 | K243615 | Physica Porous Femoral Components | Lima Corporate S.P.A. | 2024 | 1 | — |
| +7 | K223441 | SpaceFlex Acetabular Cup | G21, S.R.L. | 2023 | 0 | — |
| +7 | K221404 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 6 | — |
| +8 | K231233 | Identity™ Imprint™ CR KRS and Identity™ Imprint™ PS KRS | Conformis, Inc. | 2023 | 0 | 1 |