Devices descending from K936159
161 later devices reach Natural-Knee II System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K221479 | Persona Personalized Knee System | Zimmer, Inc. | 2022 | 8 | — |
| +1 | K173057 | Zimmer Knee Joint Replacement Prostheses MR Labeling | Zimmer, Inc. | 2018 | 5 | 2 |
| +1 | K162422 | Klassic Knee System | Total Joint Orthopedics, Inc. | 2016 | 23 | — |
| +1 | K113369 | Zimmer Persona Knee System | Zimmer, Inc. | 2012 | 96 | 39 |
| +1 | K112906 | Klassic Knee System | Total Joint Orthopedics, Inc. | 2012 | 33 | — |
| +1 | K102578 | Apex PS Knee System | Omni Life Science, Inc. | 2011 | 8 | — |
| +1 | K090705 | Balanced Knee System Ultracongruent Tibial Insert | Ortho Development Corp. | 2009 | 42 | 1 |
| +1 | K032522 | Tecres Spacer-K Temporary Knee Prosthesis | Exactech, Inc. | 2004 | 27 | — |
| +2 | K251840 | Zimmer® Persona® Personalized Knee System | Zimmer, Inc. | 2026 | 0 | — |
| +2 | K253189 | Persona the Personalized Knee System (Persona Porous Plasma Spray PPS Femurs) | Zimmer, Inc. | 2026 | 0 | — |
| +2 | K243991 | Klassic Knee System - Revision Tibial Baseplate | Total Joint Othopedics, Inc. | 2025 | 1 | — |
| +2 | K242543 | Persona the Personalized Knee System (Persona Ti-Nidium PPS Femurs) | Zimmer, Inc. | 2024 | 0 | — |
| +2 | K240299 | Persona the Personalized Knee System (Persona OsseoTi 3-Peg Patella) | Zimmer, Inc. | 2024 | 3 | — |
| +2 | K230078 | TRAX® CR Total Knee System | Amplitude | 2023 | 0 | — |
| +2 | K232414 | Klassic® Tibial Insert, PS-Post, Klassic All Poly Tibia, PS-Post | Total Joint Othopedics, Inc. | 2023 | 0 | — |
| +2 | K230537 | Klassic Knee Revision System | Total Joint Othopedics, Inc. | 2023 | 2 | — |
| +2 | K230321 | Persona™ Personalized Knee System | Zimmer, Inc. | 2023 | 0 | — |
| +2 | K222570 | COPAL knee moulds | Heraeus Medical GmbH | 2023 | 1 | — |
| +2 | K212129 | Persona® Personalized Knee System | Zimmer Switzerland Manufacturing GmbH | 2021 | 0 | — |
| +2 | K211602 | Klassic Knee System | Total Joint Orthopedics, Inc. | 2021 | 0 | — |
| +2 | K201611 | Apex Knee System | Omnilife Science | 2021 | 0 | — |
| +2 | K200209 | Persona Personalized Knee System | Zimmer, Inc. | 2020 | 2 | — |
| +2 | K193223 | Persona Personalized Knee System | Zimmer, Inc. | 2020 | 3 | — |
| +2 | K191625 | Persona Revision Knee System | Zimmer, Inc. | 2019 | 1 | 1 |
| +2 | K183596 | Klassic Knee System - Klassic Knee PS-Post Femur; Klassic Knee Tibial Insert, PS-Post… | Total Joint Orthopedics, Inc. | 2019 | 2 | — |
| +2 | K181947 | Persona Revision Knee System | Zimmer, Inc. | 2018 | 4 | 1 |
| +2 | K172524 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2018 | 15 | — |
| +2 | K180159 | Klassic® Knee System | Total Joint Orthopedics, Inc. | 2018 | 22 | — |
| +2 | K162256 | Klassic Femur, Porous, Klassic Tibial Baseplate, Porous | Total Joint Orthopedics, Inc. | 2016 | 0 | — |
| +2 | K153310 | Klassic Knee System | Total Joint Orthopedics, Inc. | 2015 | 24 | — |
| +2 | K153075 | Klassic Knee System | Total Joint Orthopedics, Inc. | 2015 | 24 | — |
| +2 | K152169 | Balanced Knee System TriMax CR Femoral Component and E-Vitalize CR and UC Tibial Inserts | Ortho Development Corporation | 2015 | 1 | — |
| +2 | K150105 | Klassic Knee System-Sombrero Patella | Total Joint Orthopedics, Inc. | 2015 | 24 | — |
| +2 | K142787 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2014 | 16 | — |
| +2 | K140833 | Itotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 26 | — |
| +2 | K140942 | Klassic Knee Tibial Stem Extension | Total Joint Orthopedics, Inc. | 2014 | 27 | — |
| +2 | K132752 | Ultracongruent Insert | United Orthopedic Corporation | 2014 | 5 | — |
| +2 | K133737 | Zimmer (R) Persona the Personalized Kee System 14X +30MM Tapered Stem Extension | Zimmer, Inc. | 2014 | 5 | — |
| +2 | K123692 | Pipeline Knee System | Pipeline Orthopedics | 2013 | 0 | — |
| +2 | K130143 | Persona Natural Tibia Baseplates | Zimmer, Inc. | 2013 | 21 | — |
| +2 | K123459 | Zimmer Persona TM Personalized Knee System | Zimmer, Inc. | 2013 | 9 | 10 |
| +2 | K122745 | Zimmer Persona the Personalized Knee System | Zimmer, Inc. | 2012 | 21 | — |
| +2 | K122765 | Persona Natural Tibia Baseplates | Zimmer, Inc. | 2012 | 25 | 2 |
| +2 | K121771 | Zimmer Persona the Personalized Knee System | Zimmer, Inc. | 2012 | 59 | 2 |
| +2 | K112891 | Apex Revision Knee Systems | Omni Life Science, Inc. | 2012 | 5 | 1 |
| +2 | K111184 | Apex PS Knee System - PS-C Insert | Omni Life Science, Inc. | 2011 | 2 | — |
| +2 | K062274 | Spacer-K Temporary Knee Spacer with Gentamicin, Models SPK0021, SPK0121, SPK0221, SPK0321 | Tecres S.P.A. | 2008 | 20 | — |
| +2 | K050210 | Disposable Cement Spacer Molds for Temporary Knee Prostheses | Biomet, Inc. | 2005 | 24 | 8 |
| +3 | K261734 | Klassic Infection Spacer System | Total Joint Orthopedics, Inc. | 2026 | 0 | — |
| +3 | K253592 | Zimmer Biomet Reverse Shoulder Prosthesis (Alliance Humeral Bearings, Identity Humeral… | Zimmer, Inc. | 2026 | 0 | — |
| +3 | K253161 | Balanced Knee System TriMax Porous Femoral Components | Ortho Development Corp. | 2025 | 0 | — |
| +3 | K243724 | Persona® Revision Knee System (Persona Revision SoluTion™ Femoral Components) | Zimmer, Inc. | 2025 | 0 | — |
| +3 | K243574 | Evolution® Total Knee Systems - Kinematic Alignment Instrumentation and Technique | Microport Orthopedics, Inc. | 2025 | 1 | — |
| +3 | K243024 | Cellbrick Knee Spacer | United Orthopedic Corporation | 2024 | 0 | — |
| +3 | K243293 | Zimmer® Persona® Personalized Knee System | Zimmer Biomet | 2024 | 1 | — |
| +3 | K243247 | Persona the Personalized Knee System | Zimmer, Inc. | 2024 | 0 | — |
| +3 | K240875 | Unity Knee PS-C Tibial Insert | Corin U.S.A. Limited | 2024 | 0 | — |
| +3 | K230471 | LinkSymphoKnee – Fixed Bearing Ultracongruent (FB UC) Articulating Surface | Waldemar Link GmbH & Co. KG | 2023 | 0 | — |
| +3 | K222566 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2022 | 2 | — |
| +3 | K222700 | Tibial baseplate, Tibial insert | United Orthopedic Corporation | 2022 | 0 | — |
| +3 | K211877 | Klassic Knee System | Total Joint Orthopedics, Inc. | 2022 | 1 | — |
| +3 | K213381 | Physica system | Lima Corporate S.P.A. | 2021 | 0 | 1 |
| +3 | K210829 | Persona Revision Knee System Femoral Metaphyseal Cones | Zimmer, Inc. | 2021 | 0 | — |
| +3 | K210551 | Persona Revision Knee System | Zimmer, Inc. | 2021 | 0 | 1 |
| +3 | K202740 | Klassic Knee System Tibial Inserts, PS-Max | Total Joint Orthopedics, Inc. | 2020 | 0 | — |
| +3 | K201343 | Triathlon Total KneeSystem | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2020 | 3 | — |
| +3 | K190562 | iTotal Identity Cruciate Retaining Knee Replacement System | Conformis, Inc. | 2019 | 15 | — |
| +3 | K190216 | SpaceFlex Knee | G21, S.R.L. | 2019 | 1 | — |
| +3 | K190068 | Vanguard XP Knee System | Zimmer, Inc. | 2019 | 0 | — |
| +3 | K183583 | Vanguard Complete Knee System | Zimmer, Inc. | 2019 | 1 | — |
| +3 | K181732 | InterSpace Knee Extra-Large Size, InterSpace Knee ATS | Tecres S.P.A. | 2019 | 1 | — |
| +3 | K190280 | Klassic Knee System - Sombrero Patella with Standard Poly, Klassic Knee System -… | Total Joint Orthopedics, Inc. | 2019 | 0 | — |
| +3 | K173890 | GMK Sphere - Kinematic Alignment | Medacta International S.A. | 2018 | 6 | — |
| +3 | K173417 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2018 | 9 | — |
| +3 | K161705 | U2 Total Knee System E-XPE products | United Orthopedic Corporation | 2017 | 1 | — |
| +3 | K161273 | StageOne Disposable Cement Spacer Molds for Temporary Knee Prosthesis | Biomet, Inc. | 2017 | 3 | 8 |
| +3 | K152430 | All Poly Tibial Component | United Orthopedic Corporation | 2016 | 0 | — |
| +3 | K153437 | Apex Revision Knee System | Omnilife Science | 2015 | 4 | 1 |
| +3 | K152252 | Arthrex iBalance TKA System | Arthrex, Inc. | 2015 | 2 | — |
| +3 | K150829 | U2 Total Knee System- Additional Sizes | United Orthopedic Corporation | 2015 | 3 | — |
| +3 | K150090 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2015 | 17 | — |
| +3 | K142404 | iTotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 24 | 2 |
| +3 | K142161 | Itotal Cruciate Retaining (CR) Knee Replacement System, Itotal Posterior Stabilized (PS)… | Conformis, Inc. | 2014 | 24 | 6 |
| +3 | K141635 | Arthrex Ibalance Tka System | Arthrex, Inc. | 2014 | 15 | — |
| +3 | K133449 | Kasm Knee Articulating Spacer Molds | Ortho Development Corp. | 2014 | 0 | — |
| +3 | K101356 | Spacer-G and Spacer-K | Tecres S.P.A. | 2011 | 19 | — |
| +4 | K253961 | SK Knee System | Just Medical Devices (Tianjin) Co., Ltd. | 2026 | 0 | — |
| +4 | K253728 | EVOLUTION® AM BIOFOAM® Tibial System | Microport Orthopedics, Inc. | 2026 | 0 | — |
| +4 | K261898 | Triathlon® Knee System; Triathlon® Hinge Knee System; Scorpio® Total Knee System | Howmedica Osteonics Corp. dba Stryker Orthopaedics | 2026 | 0 | — |
| +4 | K253637 | Triathlon® Total Knee System - Triathlon® X3® Medial Stabilized Tibial Bearing Insert | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2026 | 0 | — |
| +4 | K240856 | Hip Spacer Molds; Knee Spacer Molds; Shoulder Spacer Molds | Osartis GmbH | 2024 | 0 | — |
| +4 | K242412 | Agility Symmetric™ Total Knee System | Medisurge, LLC | 2024 | 0 | — |
| +4 | K241570 | Unity Total Knee System | Corin U.S.A. Limited | 2024 | 0 | — |
| +4 | K223316 | Identity Imprint Porous Total Knee Replacement System, Identity Imprint Porous Cruciate… | Conformis, Inc. | 2023 | 2 | — |
| +4 | K223252 | TRULIANT® E-PX Tibial Inserts; TRULIANT® E-PX Patellas | Exactech, Inc. | 2023 | 0 | 1 |
| +4 | K213287 | StageOne Knee Cement Spacer Molds | Biomet, Inc. | 2022 | 0 | — |
| +4 | K221850 | GMK 3D Metal Tibial Tray | Medacta International S.A. | 2022 | 1 | — |
| +4 | K212411 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2021 | 9 | — |
| +4 | K211609 | ATTUNE Medial Stabilized (MS) Fixed Bearing (FB) Insert | Depuy Ireland UC | 2021 | 2 | — |
| +4 | K210191 | Identity Imprint Knee Replacement System | Conformis, Inc. | 2021 | 10 | 1 |