Devices descending from K951987
254 later devices reach Genesis II Total Knee System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +5 | K243295 | Initia Knee System | Kyocera Medical Technologies, Inc. | 2025 | 0 | — |
| +5 | K242543 | Persona the Personalized Knee System (Persona Ti-Nidium PPS Femurs) | Zimmer, Inc. | 2024 | 0 | — |
| +5 | K240669 | ACTIFY™ 3D Total Knee System, ACTIFY™ Total Knee System | Globus Medical, Inc. | 2024 | 1 | — |
| +5 | K240299 | Persona the Personalized Knee System (Persona OsseoTi 3-Peg Patella) | Zimmer, Inc. | 2024 | 3 | — |
| +5 | K230120 | KeYi Total Knee System | Beijing Keyi Medical Device Technology Co., Ltd. | 2024 | 0 | — |
| +5 | K233712 | PRIMA Humeral System; PRIMA TT Glenoid | Lima Corporate S.P.A. | 2024 | 1 | — |
| +5 | K231099 | SMR Hybrid Glenoid System | Lima Corporate S.P.A. | 2023 | 0 | — |
| +5 | K223252 | TRULIANT® E-PX Tibial Inserts; TRULIANT® E-PX Patellas | Exactech, Inc. | 2023 | 0 | 1 |
| +5 | K230321 | Persona™ Personalized Knee System | Zimmer, Inc. | 2023 | 0 | — |
| +5 | K222566 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2022 | 2 | — |
| +5 | K212411 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2021 | 9 | — |
| +5 | K210829 | Persona Revision Knee System Femoral Metaphyseal Cones | Zimmer, Inc. | 2021 | 0 | — |
| +5 | K210191 | Identity Imprint Knee Replacement System | Conformis, Inc. | 2021 | 10 | 1 |
| +5 | K201611 | Apex Knee System | Omnilife Science | 2021 | 0 | — |
| +5 | K203447 | iTotal Identity Cruciate Retaining (CR) Total Knee Replacement, iTotal Identity… | Conformis, Inc. | 2020 | 12 | — |
| +5 | K201023 | iTotal® Identity Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2020 | 14 | — |
| +5 | K193223 | Persona Personalized Knee System | Zimmer, Inc. | 2020 | 3 | — |
| +5 | K191625 | Persona Revision Knee System | Zimmer, Inc. | 2019 | 1 | 1 |
| +5 | K190068 | Vanguard XP Knee System | Zimmer, Inc. | 2019 | 0 | — |
| +5 | K180906 | Conformis iTotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2018 | 17 | 4 |
| +5 | K173875 | GENFlex2 Total Knee System - Ultra-Congruent CR Tibial Insert | Stelkast, Inc. | 2018 | 2 | — |
| +5 | K162222 | GENflex2 Total Knee System | Stelkast, Inc. | 2016 | 3 | — |
| +5 | K143635 | KINETIS Total Knee System | Mako Surgical | 2015 | 0 | — |
| +5 | K142161 | Itotal Cruciate Retaining (CR) Knee Replacement System, Itotal Posterior Stabilized (PS)… | Conformis, Inc. | 2014 | 24 | 6 |
| +5 | K140833 | Itotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 26 | — |
| +5 | K140257 | Signature Planner, Signature Guides | Materialise NV | 2014 | 0 | — |
| +5 | K133256 | Itotal Cruciate Retaining, Iuni Unicondylar Knee Replacement Systems, Iduo… | Conformis, Inc. | 2014 | 16 | 6 |
| +5 | K131472 | Apex Knee Modular Tibia System | Omni Life Science, Inc. | 2013 | 5 | — |
| +6 | K252352 | SMR Shoulder System; PRIMA Glenoid System; PRIMA Humeral System | Lima Corporate S.P.A. | 2026 | 0 | — |
| +6 | K243293 | Zimmer® Persona® Personalized Knee System | Zimmer Biomet | 2024 | 1 | — |
| +6 | K243247 | Persona the Personalized Knee System | Zimmer, Inc. | 2024 | 0 | — |
| +6 | K230078 | TRAX® CR Total Knee System | Amplitude | 2023 | 0 | — |
| +6 | K213389 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System and Identity Imprint… | Conformis, Inc. | 2021 | 8 | — |
| +6 | K210809 | iTotal® Identity™ Cruciate Retaining (CR) Knee Replacement System (KRS) | Conformis, Inc. | 2021 | 4 | 1 |
| +6 | K203421 | Triathlon AS-1 | Conformis, Inc. | 2021 | 0 | — |
| +6 | K210551 | Persona Revision Knee System | Zimmer, Inc. | 2021 | 0 | 1 |
| +6 | K193105 | iUni Unicondylar Knee Replacement System, iDuo Bicompartmental Knee Repair System… | Conformis, Inc. | 2020 | 15 | — |
| +6 | K153721 | iTotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2016 | 0 | — |
| +6 | K160025 | iTotal Posterior Stabilized (PS) Knee Replacement System, iTotal Cruciate Retaining (CR)… | Conformis, Inc. | 2016 | 20 | 1 |
| +6 | K153217 | ConforMIS iTotal Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2016 | 18 | — |
| +6 | K153437 | Apex Revision Knee System | Omnilife Science | 2015 | 4 | 1 |
| +6 | K152704 | iTotal Posterior Stabilized Knee Replacement System, iTotal Cruciate Retaining Knee… | Conformis, Inc. | 2015 | 23 | — |
| +6 | K142404 | iTotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 24 | 2 |
| +7 | K253637 | Triathlon® Total Knee System - Triathlon® X3® Medial Stabilized Tibial Bearing Insert | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2026 | 0 | — |
| +7 | K230846 | iTotal Identity Knee Replacement System; Identity Imprint Knee Replacement System | Conformis, Inc. | 2023 | 2 | — |
| +7 | K230844 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System (KRS) with Cruciate… | Conformis, Inc. | 2023 | 1 | — |
| +7 | K221059 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 7 | — |
| +7 | K163332 | Apex Revision Knee System | Omnilife Science | 2017 | 3 | — |
| +7 | K161668 | ConforMIS iTotal (R) Posterior Stabilized (PS) Knee Replacement System (iTotal PS) | Conformis, Inc. | 2016 | 17 | 4 |
| +8 | K243768 | iTotal® Identity™ Cruciate Retaining 3DP Porous Knee Replacement System | Restor3D, Inc. | 2025 | 0 | — |
| +8 | K232426 | Identity Imprint Porous Cruciate Retaining (CR) Knee Replacement System (KRS) with… | Conformis, Inc. | 2023 | 0 | — |
| +8 | K221404 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 6 | — |
| +9 | K223316 | Identity Imprint Porous Total Knee Replacement System, Identity Imprint Porous Cruciate… | Conformis, Inc. | 2023 | 2 | — |
| +9 | K231233 | Identity™ Imprint™ CR KRS and Identity™ Imprint™ PS KRS | Conformis, Inc. | 2023 | 0 | 1 |