Devices descending from K952236
702 later devices reach Isola System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K191212 | CrossOver Cross Connectors, DePuy PULSE Thoracolumbar Screw System, EXPEDIUM Fenestrated… | Medos International SARL | 2019 | 0 | — |
| +1 | K063772 | Expedium Spine System | Depuy Spine, Inc. | 2007 | 264 | — |
| +1 | K982511 | Depuy Motech Moss Miami Spinal Systems | Depuy, Inc. | 1998 | 413 | — |
| +1 | K981714 | Timx Low Back System Titanium MX Rod Based Low Back System | Acromed Corp. | 1998 | 597 | — |
| +1 | K981113 | Pediatric PRC | Acromed Corp. | 1998 | 1 | — |
| +2 | K160926 | F1 MPS Modular Pedicle Screw System | Degen Medical | 2016 | 1 | — |
| +2 | K120291 | OP Spine System | OrthoPediatrics Corp. | 2012 | 138 | — |
| +2 | K110551 | Expedium Spine System | Johnson & Johnson | 2011 | 1 | — |
| +2 | K092473 | Expedium Spine System | Depuy Spine, Inc. | 2009 | 263 | — |
| +2 | K071743 | Pillar Pedicle Screw System | The 4th Column, LLC | 2007 | 0 | — |
| +2 | K070295 | Single Planar Multi Axial (Spma) Pedicle Screw System | Trinity Orthopedics, LLC | 2007 | 0 | — |
| +2 | K030383 | Modification to Moss Miami Spinal System Polyaxial Screws | Depuyacromed | 2003 | 410 | — |
| +2 | K010576 | Monarch Spine System | Depuyacromed | 2001 | 596 | — |
| +3 | K231655 | 4CIS® Chiron Spinal Fixation System | Solco Biomedical Co., Ltd. | 2024 | 0 | — |
| +3 | K190981 | NEX-D2 Posterior Fixation System | Next Orthosurgical | 2020 | 0 | — |
| +3 | K173814 | DeGen Medical E3 MIS Pedicle Screw System | Degen Medical | 2018 | 0 | — |
| +3 | K161225 | Paonan Armstrong Posterior Spinal Fixation System | Paonan Biotech Co., Ltd. | 2017 | 2 | — |
| +3 | K170821 | ChoiceSpine™ Proliant® Posterior Pedicle Screw and Hook Fixation System | Choicespine, LP | 2017 | 0 | — |
| +3 | K150600 | Response 5.5/6.0 Spine System | OrthoPediatrics Corp. | 2015 | 16 | 3 |
| +3 | K141291 | Vertiform Posterior Fixation System | Next Orthosurgical | 2014 | 2 | — |
| +3 | K141372 | Mercury Spinal System | Spinal Elements, Inc. | 2014 | 9 | — |
| +3 | K132014 | GSB Global Spinal Balance System | Nuvasive, Inc. | 2013 | 82 | — |
| +3 | K131250 | Tiger Spine System | Corelink, LLC | 2013 | 40 | — |
| +3 | K130655 | Response Spine System | OrthoPediatrics Corp. | 2013 | 17 | — |
| +3 | K123476 | Mega 5.5 Spine System | Lsk Biopartners, Inc. | 2013 | 5 | — |
| +3 | K121630 | Range Spinal System | K2m, Inc. | 2012 | 127 | — |
| +3 | K121250 | OP Spine System | OrthoPediatrics Corp. | 2012 | 18 | — |
| +3 | K110896 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2012 | 5 | — |
| +3 | K101112 | Reliance Spinal Screw System | Reliance Medical Systems | 2010 | 7 | — |
| +3 | K101070 | Expedium Spine System | Medos International SARL | 2010 | 260 | 1 |
| +3 | K093926 | Firebird Spinal Fixation System | Blackstone Medical, Inc. | 2010 | 88 | — |
| +3 | K091110 | Spinal Edge Titan Pedicle Screw System | Spinal Edge, LLC | 2009 | 1 | — |
| +3 | K081978 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2009 | 8 | — |
| +3 | K082353 | Mercury Spinal System | Spinal Elements, Inc. | 2009 | 11 | — |
| +3 | K083230 | Mercury Spinal System | Spinal Elements, Inc. | 2008 | 11 | — |
| +3 | K081252 | Expedium 4.5MM Spine System | Depuy Spine, Inc. | 2008 | 44 | — |
| +3 | K071890 | Zodiac 4.0 Polyaxial Spinal Fixation System | Alphatec Spine, Inc. | 2007 | 180 | 1 |
| +3 | K072081 | Zodiac Dynamo Semi-Rigid Spinal System | Alphatec Spine, Inc. | 2007 | 1 | — |
| +3 | K063668 | Roc Lumbar System | Alphatec Spine, Inc. | 2007 | 0 | — |
| +3 | K070245 | Capsure Pedicle Screw System | Spine Wave, Inc. | 2007 | 42 | — |
| +3 | K062513 | Apex Spine System | Spinecraft, Inc. | 2006 | 179 | — |
| +3 | K061774 | Nfix II Pedicle Screw System | N Spine, Inc. | 2006 | 2 | 7 |
| +3 | K062174 | Modification to Expedium Spine System | Depuy Spine, Inc. | 2006 | 490 | — |
| +3 | K033352 | Vertebron PSS Pedicle Screw System | Vertebron, Inc. | 2004 | 62 | — |
| +3 | K032604 | Gii Spinal Fixation System | Co-Ligne AG | 2004 | 5 | — |
| +3 | K024348 | Monarch Spine System | Depuyacromed | 2003 | 578 | — |
| +3 | K023438 | Modification to Monarch Spine System | Depuyacromed | 2002 | 4 | — |
| +3 | K021148 | Monarch Spine System Commercially Pure Titanium Spinal Rod | Depuyacromed | 2002 | 496 | — |
| +3 | K013441 | Isola Polyaxial Washer | Depuyacromed | 2001 | 262 | — |
| +4 | K253739 | SCRIPT™ Rods, CREO™ Stabilization System, REVERE® Stabilization System, REVERE® 4.5… | Globus Medical, Inc. | 2026 | 0 | — |
| +4 | K250908 | Virata Spinal Fixation System | SeaSpine Orthopedics Corporation | 2025 | 2 | 1 |
| +4 | K223181 | NuVasive Reline System | Nu Vasive, Incorporated | 2023 | 11 | — |
| +4 | K222516 | Mercury® II Spinal System | Spinal Elements, Inc. | 2022 | 3 | — |
| +4 | K211027 | Altus Spine Pedicle Screw System | Altus Partners, LLC | 2022 | 2 | — |
| +4 | K213750 | VyLink™ Spinal Screw System | Vy Spine, LLC | 2022 | 1 | — |
| +4 | K203607 | MOSS VRS Spinal System | Biedermann Motech GmbH & Co. KG | 2021 | 0 | — |
| +4 | K210306 | GII Spinal Fixation System | Coligne AG | 2021 | 0 | — |
| +4 | K210539 | CoreLink Midline Fixation System | Corelink, LLC | 2021 | 4 | — |
| +4 | K193100 | RESPONSE™ Spine System, RESPONSE™ 4.5/5.0 Spine System, RESPONSE™ 5.5/6.0 Spine System | OrthoPediatrics Corp. | 2020 | 4 | — |
| +4 | K191576 | Mercury® Spinal System, Overwatch® Spinal System | Spinal Elements, Inc. | 2019 | 5 | — |
| +4 | K180754 | C-Zero Pedicle Screw System, Freedom Pedicle Screw System | Signature Orthopaedics Pty, Ltd. | 2018 | 0 | — |
| +4 | K181390 | Response Spine System, Response 5.5/6.0 Spine System, Response 4.5/5.0 Spine System | OrthoPediatrics Corp. | 2018 | 13 | — |
| +4 | K181677 | Kodiak Spinal Fixation System | Alphatec Spine, Inc. | 2018 | 70 | — |
| +4 | K180226 | TREND II Spinal Fixation System- STEP Series | Paonan Biotech Co., Ltd. | 2018 | 1 | — |
| +4 | K172967 | Mercury® Spinal System | Spinal Elements, Inc. | 2018 | 5 | — |
| +4 | K173508 | Everest Spinal System | K2m | 2018 | 9 | — |
| +4 | K171497 | Mikron Spinal Fixation System | Mikron Makina Sanayi Ticaret Co., Ltd. | 2017 | 4 | — |
| +4 | K171832 | Range/Denali/Mesa Spinal System | K2m, Inc. | 2017 | 13 | — |
| +4 | K170861 | Premier | Shandong Weigao Orthopaedic Device Co., Ltd. | 2017 | 0 | — |
| +4 | K170126 | NuVasive® Reline® 4.5-5.0 System | Nu Vasive, Incorporated | 2017 | 39 | — |
| +4 | K162066 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2016 | 3 | — |
| +4 | K161499 | VertiForm Posterior Fixation System | Next Orthosurgical | 2016 | 1 | — |
| +4 | K161028 | K2M Growing Spine System | K2m, Inc. | 2016 | 3 | — |
| +4 | K160989 | NuVasive® Reline® System | Nu Vasive, Incorporated | 2016 | 67 | — |
| +4 | K160124 | LUMIS Cannulated Pedicle Screw Fixation System, U.L.I.S. Pedicle Screw Fixation System | Spinevision S.A. | 2016 | 2 | — |
| +4 | K160466 | Response 5.5 Spine System | OrthoPediatrics Corp. | 2016 | 1 | — |
| +4 | K151648 | Altus Spine Pedicle Screw System, Altus Spine MIS Pedicle Screw System, Valencia Pedicle… | Altus Partners, LLC | 2015 | 5 | — |
| +4 | K152131 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2015 | 4 | — |
| +4 | K151215 | Mercury Spinal System | Spinal Elements, Inc. | 2015 | 8 | — |
| +4 | K143683 | APEX-DL Spine System | Spinecraft, LLC | 2015 | 3 | — |
| +4 | K150417 | Astra Spine System | Spinecraft, LLC | 2015 | 21 | — |
| +4 | K143684 | NuVasive Reline System | Nu Vasive, Incorporated | 2015 | 77 | — |
| +4 | K142737 | MAS PLIF Fixation system | Nu Vasive, Incorporated | 2014 | 1 | — |
| +4 | K142499 | Reline System | Nu Vasive, Incorporated | 2014 | 78 | — |
| +4 | K141873 | Range/Mesa/Denali Spinal System | K2m, Inc. | 2014 | 30 | — |
| +4 | K140765 | Range/Mesa/Denali Spinal System | K2m, Inc. | 2014 | 15 | — |
| +4 | K133575 | Spinevision Lumis Cannulated Pedicle Screw Fixation System, Spinevision U.L.I.S. Pedicle… | Spinevision S.A. | 2014 | 3 | — |
| +4 | K140678 | Cosmolock Pedicle Screw System | Kalitec Direct, LLC | 2014 | 10 | — |
| +4 | K141147 | Range Spinal System | K2m, Inc. | 2014 | 1 | — |
| +4 | K140696 | Streamline TL Spinal Fixation System | Pioneer Surgical Technology, Inc. | 2014 | 5 | — |
| +4 | K133944 | Range, Spinal System, Everest Spinal System | K2m, Inc. | 2014 | 33 | — |
| +4 | K133369 | Tiger Spine System | Corelink, LLC | 2014 | 29 | — |
| +4 | K132403 | Annextm Adjacent Level System | Spine Wave, Inc. | 2014 | 2 | — |
| +4 | K132603 | Apex Spine System | Spinecraft, LLC | 2013 | 25 | — |
| +4 | K132757 | Everest Spinal System | K2m, Inc. | 2013 | 41 | — |
| +4 | K132280 | Altus Spine Pedicle Screw System | Altus Partners | 2013 | 6 | — |
| +4 | K131784 | Range Spinal System | K2m, Inc. | 2013 | 34 | — |
| +4 | K131810 | Osseus Black Diamond Pedicle Screw System | Osseus Fusion Systems, LLC | 2013 | 14 | — |
| +4 | K130932 | Firebird Spinal Fixation System | Orthofix, Inc. | 2013 | 81 | 1 |
| +4 | K130877 | Expedium Spine System | Medos International SARL | 2013 | 8 | — |