Devices descending from K991581
348 later devices reach Nexgen Complete Knee Solution Legacy Posterior Stabilized (LPS); LPS-Flex… through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +3 | K242412 | Agility Symmetric™ Total Knee System | Medisurge, LLC | 2024 | 0 | — |
| +3 | K242711 | JOURNEY II Unicompartmental Knee System (JOURNEY II UK) | Smith & Nephew, Inc. | 2024 | 0 | — |
| +3 | K234044 | ACS® LD FB Knee System | Implantcast GmbH | 2024 | 1 | — |
| +3 | K240299 | Persona the Personalized Knee System (Persona OsseoTi 3-Peg Patella) | Zimmer, Inc. | 2024 | 3 | — |
| +3 | K231975 | PNK Total Knee System | Tjc Life Co., Ltd. | 2023 | 0 | — |
| +3 | K233093 | Balanced Knee® System TriMax PS Plus Tibial Insert | Ortho Development Corporation | 2023 | 0 | — |
| +3 | K223316 | Identity Imprint Porous Total Knee Replacement System, Identity Imprint Porous Cruciate… | Conformis, Inc. | 2023 | 2 | — |
| +3 | K230555 | Cemented Tibia Baseplate no Taper with JRNY Lock | Smith & Nephew, Inc. | 2023 | 0 | — |
| +3 | K230471 | LinkSymphoKnee – Fixed Bearing Ultracongruent (FB UC) Articulating Surface | Waldemar Link GmbH & Co. KG | 2023 | 0 | — |
| +3 | K223548 | GMK Sphere & GMK SpheriKA Cementless | Medacta International S.A. | 2023 | 1 | — |
| +3 | K222566 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2022 | 2 | — |
| +3 | K221850 | GMK 3D Metal Tibial Tray | Medacta International S.A. | 2022 | 1 | — |
| +3 | K220896 | Legion Inserts with JRNY Lock | Smith & Nephew, Inc. | 2022 | 1 | — |
| +3 | K213381 | Physica system | Lima Corporate S.P.A. | 2021 | 0 | 1 |
| +3 | K211671 | Journey II Mid-Level Tibial Inserts | Smith & Nephew, Inc. | 2021 | 1 | — |
| +3 | K211664 | GMK Sphere Revision | Medacta International S.A. | 2021 | 0 | — |
| +3 | K210829 | Persona Revision Knee System Femoral Metaphyseal Cones | Zimmer, Inc. | 2021 | 0 | — |
| +3 | K211004 | GMK Spherika Femurs and Fixed Tibial Trays Plus | Medacta International S.A. | 2021 | 4 | — |
| +3 | K210961 | U2 Total Knee System, XPE Tibial Insert, PS PLUS | United Orthopedic Corporation | 2021 | 0 | — |
| +3 | K210551 | Persona Revision Knee System | Zimmer, Inc. | 2021 | 0 | 1 |
| +3 | K202684 | GMK Total Knee System - TiNbN Coating | Medacta International S.A. | 2020 | 3 | — |
| +3 | K202022 | GMK-SPHERE Tibial inserts FLEX Tibial Insert CR and Resurfacing Patella made of E-CROSS… | Medacta International S.A. | 2020 | 1 | — |
| +3 | K201343 | Triathlon Total KneeSystem | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2020 | 3 | — |
| +3 | K200122 | MOTO PFJ System | Medacta International S.A. | 2020 | 2 | — |
| +3 | K200407 | LEGION Inserts with JRNY Lock | Smith & Nephew, Inc. | 2020 | 2 | — |
| +3 | K193284 | Physica LMC Knee System | Lima Corporate S.P.A. | 2020 | 6 | — |
| +3 | K190068 | Vanguard XP Knee System | Zimmer, Inc. | 2019 | 0 | — |
| +3 | K183583 | Vanguard Complete Knee System | Zimmer, Inc. | 2019 | 1 | — |
| +3 | K173890 | GMK Sphere - Kinematic Alignment | Medacta International S.A. | 2018 | 6 | — |
| +3 | K181635 | GMK Sphere CR Tibial Inserts | Medacta International S.A. | 2018 | 2 | — |
| +3 | K173417 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2018 | 9 | — |
| +3 | K173331 | JOURNEY II XR Knee Instruments | Smith & Nephew, Inc. | 2017 | 1 | 4 |
| +3 | K171365 | Arthrex Knee Systems | Arthrex, Inc. | 2017 | 0 | — |
| +3 | K170648 | ANTHEM CR Total Knee System | Smith & Nephew, Inc. | 2017 | 4 | — |
| +3 | K162035 | GMK Sphere | Medacta International S.A. | 2017 | 10 | — |
| +3 | K151256 | Arthrex BioSync® Bone Wedge | Arthex, Inc. | 2015 | 10 | 6 |
| +3 | K150090 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2015 | 17 | — |
| +3 | K143226 | Visionaire Disposable Instruments | Smith & Nephew, Inc. | 2015 | 0 | — |
| +3 | K142404 | iTotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 24 | 2 |
| +3 | K141471 | Journey II XR Knee System | Smith & Nephew, Inc. | 2014 | 12 | — |
| +3 | K142161 | Itotal Cruciate Retaining (CR) Knee Replacement System, Itotal Posterior Stabilized (PS)… | Conformis, Inc. | 2014 | 24 | 6 |
| +3 | K141585 | Smith & Nephew Disposable Fin Punch | Smith & Nephew, Inc. | 2014 | 0 | — |
| +3 | K140826 | GMK Sphere Extension | Medacta International | 2014 | 17 | — |
| +3 | K131368 | Neo Knee System | Pipeline Orthopedics | 2013 | 1 | — |
| +3 | K123721 | GMK Revision Extension | Medacta International | 2013 | 3 | — |
| +3 | K122160 | Vanguard XP Knee System | Biomet Manufacturing Corp | 2013 | 6 | 12 |
| +3 | K122870 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2013 | 33 | — |
| +3 | K122991 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 26 | — |
| +3 | K122232 | GMK Narrow | Medacta International | 2012 | 8 | — |
| +3 | K122033 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 26 | — |
| +3 | K121443 | Journey II CR Knee System | Smith & Nephew, Inc. | 2012 | 37 | — |
| +3 | K120316 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 36 | — |
| +3 | K113378 | Conformis Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2012 | 36 | — |
| +3 | K120068 | Conformis Itotal CR Knee Replacement System (KRS) | Conformis, Inc. | 2012 | 36 | — |
| +3 | K112780 | Conformis Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2011 | 38 | — |
| +3 | K110950 | Consensus Knee System | Consensus Orthopedics, Inc. | 2011 | 14 | — |
| +3 | K110240 | Smith & Nephew, Inc. Sureshot Distal Targeting System V2.1 | Smith & Nephew, Inc. | 2011 | 2 | — |
| +3 | K103170 | GMK Revision Knee SC Liners | Medacta International S.A. | 2011 | 28 | — |
| +3 | K103721 | Mpact Acetabular System | Medacta International | 2011 | 21 | — |
| +3 | K103352 | Versafitcup CC Trio | Medacta International | 2011 | 4 | — |
| +3 | K102927 | Consensus Knee System | Consensus Orthopedics, Inc. | 2011 | 0 | — |
| +3 | K103117 | Itotal Cruciate Retaining (CR) Knee Replacement System | Conformis, Inc. | 2011 | 40 | 1 |
| +3 | K102437 | GMK Revision Knee System | Medacta International S.A. | 2010 | 34 | — |
| +3 | K093746 | Verilast Wear Claims for the Legion Primary Knee System | Smith & Nephew, Inc. | 2010 | 29 | — |
| +3 | K093806 | Myknee Cutting Blocks | Medacta International S.A. | 2010 | 16 | — |
| +3 | K073286 | Gender Solutions Natural-Knee Flex System | Zimmer, Inc. | 2008 | 117 | 5 |
| +3 | K072160 | Nexgen Trabecular Metal Tibial Tray | Zimmer, Inc. | 2007 | 108 | 1 |
| +3 | K051229 | Profix Flex Cruciate Retaining Articular Insert | Smith & Nephew, Inc. | 2005 | 14 | — |
| +3 | K041100 | Nexgen Porous, HA/TCP, Uncemented Femoral and Tibial Baseplate Components | Zimmer, Inc. | 2004 | 6 | 3 |
| +4 | K253961 | SK Knee System | Just Medical Devices (Tianjin) Co., Ltd. | 2026 | 0 | — |
| +4 | K253630 | Mpact 3D Metal Foam | Medacta International S.A. | 2026 | 0 | — |
| +4 | K253728 | EVOLUTION® AM BIOFOAM® Tibial System | Microport Orthopedics, Inc. | 2026 | 0 | — |
| +4 | K261898 | Triathlon® Knee System; Triathlon® Hinge Knee System; Scorpio® Total Knee System | Howmedica Osteonics Corp. dba Stryker Orthopaedics | 2026 | 0 | — |
| +4 | K260037 | implantcast Packaging System Update | Implantcast GmbH | 2026 | 0 | — |
| +4 | K253328 | GMK 3D Metal Tibial Tray Extension | Medacta International S.A. | 2026 | 0 | — |
| +4 | K251043 | Mpact 3D Metal Implants Extension – DMLS Technology | Medacta International S.A. | 2026 | 0 | — |
| +4 | K250450 | Coated hip implants | Medacta International S.A. | 2025 | 0 | — |
| +4 | K241461 | Mpact Constrained Liner | Medacta International S.A. | 2025 | 1 | — |
| +4 | K250677 | LEGION Total Knee System | Smith & Nephew, Inc. | 2025 | 0 | — |
| +4 | K243768 | iTotal® Identity™ Cruciate Retaining 3DP Porous Knee Replacement System | Restor3D, Inc. | 2025 | 0 | — |
| +4 | K241180 | Consensus Knee System with TiNbN | Shalby Advanced Technologies | 2025 | 1 | — |
| +4 | K243293 | Zimmer® Persona® Personalized Knee System | Zimmer Biomet | 2024 | 1 | — |
| +4 | K240461 | OsteoSinter® EVANS and COTTON wedges and related accessories | Ames Medical Prosthetic Solutions, S.A.U. | 2024 | 2 | — |
| +4 | K243247 | Persona the Personalized Knee System | Zimmer, Inc. | 2024 | 0 | — |
| +4 | K241570 | Unity Total Knee System | Corin U.S.A. Limited | 2024 | 0 | — |
| +4 | K230011 | Mpact Extension | Medacta International S.A. | 2023 | 3 | — |
| +4 | K232426 | Identity Imprint Porous Cruciate Retaining (CR) Knee Replacement System (KRS) with… | Conformis, Inc. | 2023 | 0 | — |
| +4 | K231037 | MyKnee UNI-ST | Medacta International S.A. | 2023 | 0 | — |
| +4 | K202568 | Mpact® 3D Metal Implants - DMLS Technology | Medacta International S.A. | 2021 | 1 | — |
| +4 | K213071 | MOTOTM Partial Knee & MOTO PFJ Systems Extension | Medacta International S.A. | 2021 | 1 | — |
| +4 | K211609 | ATTUNE Medial Stabilized (MS) Fixed Bearing (FB) Insert | Depuy Ireland UC | 2021 | 2 | — |
| +4 | K211938 | Physica LMC Knee System | Limacorporate | 2021 | 0 | — |
| +4 | K200391 | MPACT Extension | Medacta International S.A. | 2021 | 0 | — |
| +4 | K210010 | GMK Revision & Hinge Extension - TiNbN Coating | Medacta International S.A. | 2021 | 1 | — |
| +4 | K203755 | Shoulder System - TiNbN Coating | Medacta International S.A. | 2021 | 0 | — |
| +4 | K201084 | Physica system | Lima Corporate S.P.A. | 2020 | 5 | — |
| +4 | K193559 | NextAR TKA Platform | Medacta Inernational SA | 2020 | 12 | — |
| +4 | K200227 | Journey II XR Knee Instrument | Smith & Nephew, Inc. | 2020 | 0 | — |
| +4 | K193414 | Trigon HA Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2020 | 6 | — |
| +4 | K192645 | Trigon™ Ti Stand-Alone Wedge Fixation System | Nvision Biomedical Technologies, Inc. | 2019 | 7 | — |