Devices descending from K012591
90 later devices reach Advance Unicondylar Knee System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K100973 | Evolution Unicondylar Knee System | Wrightmedicaltechnologyinc | 2010 | 0 | — |
| +1 | K090024 | TGS Unicompartmental Knee Arthroplasty System | Alexandria Research Technologies, LLC | 2009 | 1 | — |
| +1 | K053299 | Repicci II Onlay Unicompartmental Tibial Component | Biomet Manufacturing, Inc. | 2006 | 0 | — |
| +1 | K033810 | Natural-Knee II Unicompartmental Knee System | Centerpulse Orthopedics, Inc. | 2004 | 20 | 1 |
| +1 | K022437 | Uni Knee | Encore Medical L.P. | 2002 | 80 | 2 |
| +1 | K020741 | Unicondylar Knee | Encore Orthopedics, Inc. | 2002 | 81 | 2 |
| +1 | K014171 | Advance Unicondylar Knee System | Wrightmedicaltechnologyinc | 2002 | 3 | — |
| +2 | K170344 | Tahoe Uni Knee System | Consensus Orthopedics, Inc. | 2017 | 1 | — |
| +2 | K133811 | Restoris Porous Partial Knee System | Mako Surgical Corp. | 2014 | 19 | — |
| +2 | K101206 | TGS Unicompartmental Knee Arthroplasty (TGS Uka) Modular Tibia System | Alexandria Research Technologies, LLC | 2010 | 0 | — |
| +2 | K082081 | Mako Surgical Corporation Unicondylar Knee Implant System Iii | Mako Surgical Corp. | 2008 | 12 | — |
| +2 | K080368 | Mako Surgical Corp. Unicondylar Knee Implant System II | Mako Surgical Corp. | 2008 | 56 | — |
| +2 | K072368 | Conformis Metal Backed Tibial Component | Conformis, Inc. | 2007 | 31 | 3 |
| +2 | K022211 | HLS Uni Evolution Prosthesis | Tornier | 2003 | 1 | — |
| +3 | K260796 | Tahoe Unicondylar Knee System with TiNbN Overcoat | Shalby Advanced Technologies, Inc. Dba Consensus Orthopedics | 2026 | 0 | — |
| +3 | K242307 | ACHIEVE Partial Knee System | Ignite Orthomotion | 2024 | 1 | — |
| +3 | K190633 | NanoOrtho NanoKnee® System | Nanoortho, LLC | 2019 | 0 | — |
| +3 | K190439 | Engage™ Partial Knee System | Engage Uni, LLC | 2019 | 5 | 4 |
| +3 | K163700 | Bodycad Unicompartmental Knee System | Bodycad Laboratories, Inc. | 2017 | 8 | — |
| +3 | K150410 | Restoris Porous Partial Knee System | Mako Surgical Corporation | 2015 | 0 | — |
| +3 | K123380 | Stride Unicondylar Knee | Blue Belt Technologies, Inc. | 2013 | 11 | 2 |
| +3 | K121974 | Conformis Iuni Unicondylar Knee Replacement System | Conformis, Inc. | 2012 | 27 | — |
| +3 | K120262 | HLS Uni Evolution & U-Kneetec | Tornier, Inc. | 2012 | 0 | — |
| +3 | K111916 | Conformis Iuni Unicondylar Knee Replacement System | Conformis, Inc. | 2011 | 28 | — |
| +3 | K092441 | Modification to: Conformis Iuni Unicondylar Knee Repair System | Conformis, Inc. | 2009 | 29 | — |
| +3 | K082172 | Mako Modular Knee Compartmental Implant System | Mako Surgical Corporation | 2008 | 51 | 2 |
| +3 | K080936 | Conformis Total Knee Repiar System (Itotal) Tibial Component: 6.0 MM Thickness | Conformis, Inc. | 2008 | 0 | — |
| +4 | K251975 | Achieve Partial Knee System - Porous Coated CoCrMo Femoral Component | Ignite Orthomotion | 2025 | 0 | — |
| +4 | K230653 | Smith & Nephew, Inc. ANTHEM Total Knee System, Genesis Uni Knee System, JOURNEY BCS and… | Smith & Nephew, Inc. | 2023 | 3 | 1 |
| +4 | K222653 | JOURNEY II UK™ and ENGAGE™ Cementless Partial Knee System | Smith+Nephew, Inc. | 2022 | 0 | — |
| +4 | K203341 | ACS LD Uni FB Knee System | Implantcast GmbH | 2021 | 1 | — |
| +4 | K191996 | BC Reflex Uni Knee System | Bodycad Laboratories, Inc. | 2019 | 3 | — |
| +4 | K191150 | Bodycad Unicompartmental Knee System | Bodycad Laboratories, Inc. | 2019 | 4 | — |
| +4 | K181302 | Bodycad Unicompartmental Knee System | Bodycad Laboratories, Inc. | 2019 | 7 | — |
| +4 | K133256 | Itotal Cruciate Retaining, Iuni Unicondylar Knee Replacement Systems, Iduo… | Conformis, Inc. | 2014 | 16 | 6 |
| +4 | K132640 | Iuni Unicondylar Knee Replacement System | Conformis, Inc. | 2013 | 25 | 3 |
| +4 | K090763 | Restoris Multicompartmental Knee (MCK) System | Mako Surgical Corporation | 2009 | 50 | 5 |
| +5 | K261462 | LANDMARK Total Knee System | Smith & Nephew, Inc. | 2026 | 0 | — |
| +5 | K260037 | implantcast Packaging System Update | Implantcast GmbH | 2026 | 0 | — |
| +5 | K241260 | ACTIFY™ Unicondylar Knee System | Globus Medical, Inc. | 2024 | 0 | — |
| +5 | K242711 | JOURNEY II Unicompartmental Knee System (JOURNEY II UK) | Smith & Nephew, Inc. | 2024 | 0 | — |
| +5 | K212307 | BC Reflex Uni Knee System | Bodycad Laboratories, Inc. | 2021 | 0 | — |
| +5 | K203697 | BC Reflex Uni Knee System | Bodycad Laboratories, Inc. | 2021 | 2 | — |
| +5 | K193105 | iUni Unicondylar Knee Replacement System, iDuo Bicompartmental Knee Repair System… | Conformis, Inc. | 2020 | 15 | — |
| +5 | K172326 | Triathlon Total Knee System, Triathlon PKR System, Restoris MCK Knee System | Stryker Orthopaedics | 2017 | 24 | 1 |
| +5 | K160461 | Arthrex iBalance BiCompartmental Arthroplasty System | Arthrex, Inc. | 2016 | 3 | — |
| +5 | K133039 | Restoris Multicompartmental Knee System | Mako Surgical Corporation | 2013 | 26 | — |
| +6 | K261898 | Triathlon® Knee System; Triathlon® Hinge Knee System; Scorpio® Total Knee System | Howmedica Osteonics Corp. dba Stryker Orthopaedics | 2026 | 0 | — |
| +6 | K251665 | Triathlon® Hinge Knee System | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2025 | 2 | — |
| +6 | K242831 | Triathlon Knee System; Triathlon Pro Posterior Stabilized Femoral Components; Triathlon… | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2024 | 3 | — |
| +6 | K230952 | Triathlon® Total Knee System - Triathlon® Pro Posterior Stabilized (PS) Femoral Component | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2023 | 4 | — |
| +6 | K230416 | Triathlon® Hinge Knee System; Triathlon® Revision Insert X3® | Stryker | 2023 | 3 | — |
| +6 | K223528 | Triathlon® Hinge Knee System | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2023 | 4 | 1 |
| +6 | K211895 | BC Reflex Uni Knee System | Bodycad Laboratories, Inc. | 2021 | 0 | — |
| +6 | K203099 | Triathlon PKR System | Howmedica Osteonics Corp. A.K.A. Stryker Orthopaedics | 2020 | 1 | — |
| +6 | K201343 | Triathlon Total KneeSystem | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2020 | 3 | — |
| +6 | K201023 | iTotal® Identity Posterior Stabilized Knee Replacement System | Conformis, Inc. | 2020 | 14 | — |
| +6 | K200782 | Triathlon Posterior Stabilized Femoral Component - beaded with Peri-Apatite, Triathlon… | Howmedica Osteonics Corp. | 2020 | 0 | — |
| +6 | K200395 | LOSPA II Knee System (EXULT Knee Replacement System) | Corentec Co., Ltd. | 2020 | 2 | — |
| +6 | K200433 | iBalance UKA Tibial Tray Implant | Arthrex, Inc. | 2020 | 1 | — |
| +6 | K190402 | Triathlon Total Knee System-Additional Components | Stryker Orthopaedics (Aka Howmedica Osteonics Corp.) | 2019 | 11 | — |
| +6 | K190991 | Triathlon Tritanium Central Femoral Cone Augment, Triathlon Femoral Distal Augment | Howmedica Osteonics Corp. (Aka Stryker Orthopaedics) | 2019 | 0 | 4 |
| +6 | K180612 | Triathlon PKR X3 Tibial Inserts, Mako X3 Uni Onlay Tibial Inserts | Howmedica Osteonics Corp. A.K.A. Stryker Orthopaedics | 2018 | 3 | — |
| +6 | K173849 | Triathlon Total Knee System | Stryker Orthopaedics | 2018 | 14 | 3 |
| +6 | K171365 | Arthrex Knee Systems | Arthrex, Inc. | 2017 | 0 | — |
| +6 | K150307 | RESTORIS Multicompartmental Knee System | Mako Surgical Corp. | 2015 | 25 | — |
| +7 | K253637 | Triathlon® Total Knee System - Triathlon® X3® Medial Stabilized Tibial Bearing Insert | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2026 | 0 | — |
| +7 | K252898 | Triathlon® Tritanium® Asymmetric Patella; Triathlon® Tritanium® Symmetric Patella… | Howmedica Osteonics Corp., Dba Stryker Orthopaedics | 2025 | 0 | 1 |
| +7 | K251453 | Arthrex iBalance Partial Knee System | Arthrex, Inc. | 2025 | 0 | — |
| +7 | K240669 | ACTIFY™ 3D Total Knee System, ACTIFY™ Total Knee System | Globus Medical, Inc. | 2024 | 1 | — |
| +7 | K221850 | GMK 3D Metal Tibial Tray | Medacta International S.A. | 2022 | 1 | — |
| +7 | K220930 | Restoris Multi-Compartmental Knee System | Mako Surgical Corp. | 2022 | 0 | — |
| +7 | K212034 | LOSPA TKR System | Corentec Co., Ltd. | 2021 | 0 | — |
| +7 | K212411 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2021 | 9 | — |
| +7 | K210191 | Identity Imprint Knee Replacement System | Conformis, Inc. | 2021 | 10 | 1 |
| +7 | K203421 | Triathlon AS-1 | Conformis, Inc. | 2021 | 0 | — |
| +7 | K203447 | iTotal Identity Cruciate Retaining (CR) Total Knee Replacement, iTotal Identity… | Conformis, Inc. | 2020 | 12 | — |
| +7 | K201851 | EXULT Femoral component trial - Left, EXULT Femoral component trial - Right | Corentec Co., Ltd. | 2020 | 0 | — |
| +8 | K262251 | ACTIFY™ Total Knee System, ACTIFY™ 3D Total Knee System (ACTIFY MC Tibial Insert) | Globus Medical, Inc. | 2026 | 0 | — |
| +8 | K253328 | GMK 3D Metal Tibial Tray Extension | Medacta International S.A. | 2026 | 0 | — |
| +8 | K213389 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System and Identity Imprint… | Conformis, Inc. | 2021 | 8 | — |
| +8 | K210809 | iTotal® Identity™ Cruciate Retaining (CR) Knee Replacement System (KRS) | Conformis, Inc. | 2021 | 4 | 1 |
| +9 | K230846 | iTotal Identity Knee Replacement System; Identity Imprint Knee Replacement System | Conformis, Inc. | 2023 | 2 | — |
| +9 | K230844 | Identity Imprint Cruciate Retaining (CR) Knee Replacement System (KRS) with Cruciate… | Conformis, Inc. | 2023 | 1 | — |
| +9 | K221059 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 7 | — |
| +10 | K243768 | iTotal® Identity™ Cruciate Retaining 3DP Porous Knee Replacement System | Restor3D, Inc. | 2025 | 0 | — |
| +10 | K232426 | Identity Imprint Porous Cruciate Retaining (CR) Knee Replacement System (KRS) with… | Conformis, Inc. | 2023 | 0 | — |
| +10 | K221404 | Identity Imprint Knee Replacement System (including Identity Imprint Posterior… | Conformis, Inc. | 2022 | 6 | — |
| +11 | K223316 | Identity Imprint Porous Total Knee Replacement System, Identity Imprint Porous Cruciate… | Conformis, Inc. | 2023 | 2 | — |
| +11 | K231233 | Identity™ Imprint™ CR KRS and Identity™ Imprint™ PS KRS | Conformis, Inc. | 2023 | 0 | 1 |