Devices descending from K022285
403 later devices reach Modification to Isola Spinal System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +8 | K213281 | PASS LP™ Spinal System, CD Horizon™ Spinal System | Medicrea International SA | 2022 | 0 | — |
| +8 | K211616 | ExcelsiusHub | Globus Medical, Inc. | 2021 | 9 | Class I |
| +8 | K201569 | CUVIS-spine | Curexo, Inc. | 2021 | 2 | — |
| +8 | K202184 | Practical Navigation Surgical Guidance System (PNSGS) | Practical Navigation, LLC | 2021 | 5 | — |
| +8 | K203319 | SYMPHONY™ OCT System | Medos International SARL | 2021 | 1 | — |
| +8 | K200922 | Altus Spine HA Pedicle Screw System | Altus Partners, LLC | 2021 | 3 | — |
| +8 | K203452 | Nano FortiFix® System | Nanovis, LLC | 2020 | 0 | — |
| +8 | K203125 | Invictus™ OCT Spinal Fixation System | Alphatec Spine, Inc. | 2020 | 0 | — |
| +8 | K203056 | Invictus™ Spinal Fixation System | Alphatec Spine, Inc. | 2020 | 61 | — |
| +8 | K202327 | Invictus™ OsseoScrew® System | Alphatec Spine, Inc. | 2020 | 0 | — |
| +8 | K200047 | ExcelsiusGPS Cranial 1.0 Module | Globus Medical, Inc. | 2020 | 5 | 3 |
| +8 | K200936 | Invictus™ CT Spinal Fixation System | Alphatec Spine, Inc. | 2020 | 3 | — |
| +8 | K191100 | ExcelsiusGPS Spine 1.1 Interbody Module | Globus Medical, Inc. | 2019 | 42 | — |
| +8 | K191045 | Salvo™ Spine System | Spine Wave, Inc. | 2019 | 5 | — |
| +8 | K183119 | SI-LOK® Sacroiliac Joint Fixation System, Navigation Instruments, ExcelsiusGPS®… | Globus Medical, Inc. | 2019 | 2 | — |
| +8 | K182000 | AQrate Robotic Assistance System | Globus Medical, Inc. | 2019 | 1 | — |
| +8 | K182508 | Saxxony™ Posterior Cervical Thoracic System | Nexxt Spine, LLC | 2018 | 4 | — |
| +8 | K181350 | ASTRA-OCT Spine System | Spinecraft, LLC | 2018 | 0 | — |
| +8 | K162750 | Libra Pedicle Screw System | Spinal Balance, Inc. | 2016 | 0 | — |
| +8 | K161591 | QUARTEX™ Occipito-Cervico-Thoracic Spinal System, Globus Navigation Instruments | Globus Medical, Inc. | 2016 | 78 | — |
| +8 | K153370 | Caspian OCT/MESA Mini/DENALI Mini Spinal System | K2m, Incorporated | 2016 | 17 | — |
| +8 | K151196 | Nautilus Spinal System | Life Spine, Inc. | 2015 | 12 | — |
| +9 | K253943 | Tiger 2 System | Zavation Medical Products, LLC | 2026 | 0 | — |
| +9 | K260369 | Dynamis Robotic Surgical System | LEM Surgical AG | 2026 | 0 | — |
| +9 | K261665 | CORUS™ Navigation System-GN | Providence Medical Technology, Inc. | 2026 | 0 | — |
| +9 | K253940 | M.U.S.T. Pedicle Screw System - Extension | Medacta International S.A. | 2026 | 0 | — |
| +9 | K250599 | ExcelsiusGPS™ Instruments | Globus Medical, Inc. | 2025 | 0 | — |
| +9 | K252322 | SIros-X System | Genesys Spine | 2025 | 0 | — |
| +9 | K253094 | iFuse Bedrock Granite Implant System | SI-BONE, Inc. | 2025 | 0 | — |
| +9 | K252437 | JAZZ Spinal System | Implanet | 2025 | 0 | — |
| +9 | K251060 | CORUS™ Navigation System-GX | Providence Medical Technology, Inc. | 2025 | 0 | — |
| +9 | K251154 | RIVA Posterior Fixation System; RIVA Posterior Fixation System Navigation Instruments | Ht Medical D.B.A. Xenix Medical | 2025 | 1 | — |
| +9 | K242674 | Freedom Posterior Cervical Screws | Signature Orthopaedics Pty, Ltd. | 2025 | 0 | — |
| +9 | K242516 | EUROPA™ Posterior Cervical Fusion System | MiRus, LLC | 2024 | 2 | — |
| +9 | K241892 | Cortera™ Spinal Fixation System | Xtant Medical Holdings, Inc. | 2024 | 2 | — |
| +9 | K233228 | Spine Navigation and Robotic-Assistance Device | Ecential Robotics | 2024 | 2 | 1 |
| +9 | K240392 | JAZZ Spinal System | Implanet | 2024 | 1 | — |
| +9 | K231923 | Liberty SI Lateral Implant System | Spinal Simplicity, LLC | 2023 | 0 | — |
| +9 | K233366 | SYMPHONY OCT System | Medos International SARL | 2023 | 0 | — |
| +9 | K232311 | LnK Spinal Fixation System /OpenLoc-L Spinal Fixation System, AccelFix Spinal Fixation… | L&K BIOMED Co., Ltd. | 2023 | 1 | — |
| +9 | K223070 | Remi Robotic Navigation System | Fusion Robotics, LLC | 2022 | 4 | — |
| +9 | K222270 | HEDRON Cervical Spacers, HEDRON Lumbar Spacers, SABLE Expandable Spacer, ExcelsiusGPS… | Globus Medical, Inc. | 2022 | 23 | — |
| +9 | K222698 | CUVIS-spine | Curexo, Inc. | 2022 | 0 | — |
| +9 | K211027 | Altus Spine Pedicle Screw System | Altus Partners, LLC | 2022 | 2 | — |
| +9 | K212962 | TRELLIS™ SI Joint Fusion System | Orthofundamentals, LLC | 2022 | 0 | — |
| +9 | K213460 | Invictus Spinal Fixation System | Alphatec Spine, Inc. | 2021 | 17 | — |
| +9 | K211957 | QUARTEX Occipito-Cervico-Thoracic Spinal System, Globus Navigation Instruments | Globus Medical, Inc. | 2021 | 3 | — |
| +9 | K203742 | IdentiTi ALIF Standalone Interbody System | Alphatec Spine, Inc. | 2021 | 59 | — |
| +9 | K202476 | Salvo® Spine System | Spine Wave, Inc. | 2020 | 4 | — |
| +9 | K182182 | YUKON OCT Spinal System | K2m | 2018 | 5 | — |
| +9 | K180690 | Navigation Instruments | Globus Medical, Inc. | 2018 | 9 | — |
| +9 | K171444 | YUKON OCT Spinal System | K2m, Inc. | 2017 | 13 | 3 |
| +9 | K162266 | The Cranial Fusion System | Life Spine, Inc. | 2017 | 1 | — |
| +10 | K262193 | RIVA® Posterior Fixation System with NanoACTIV Surface Technology; RIVA® Anchor… | Xenix Medical | 2026 | 0 | — |
| +10 | K261113 | Op.n™ Spine Navigation and Robotic Guidance | Ecential Robotics | 2026 | 1 | — |
| +10 | K261130 | AccelFix Spinal Fixation System | L&K BIOMED Co., Ltd. | 2026 | 0 | — |
| +10 | K253401 | SCRIPT™ Implant System | Globus Medical, Inc. | 2026 | 0 | — |
| +10 | K253876 | HEDRON™ Cervical Spacers (HEDRON C-MIS™ Spacer) | Globus Medical, Inc. | 2025 | 1 | — |
| +10 | K243946 | EffortMed Spinal Fixation System | Effortmed, LLC | 2025 | 1 | — |
| +10 | K243635 | aprevo® anterior lumbar interbody fusion device with interfixation | Carlsmed, Inc. | 2024 | 5 | — |
| +10 | K234035 | COSINE™ Spacer | Globus Medical, Inc. | 2024 | 0 | — |
| +10 | K241846 | E3D™-C Interbody System | Evolution Spine | 2024 | 6 | — |
| +10 | K234077 | SPIRA® Anterior Lumbar Spacers | Camber Spine Technologies | 2024 | 0 | — |
| +10 | K232413 | Fusion Robotic Navigation System | Alphatec Spine, Inc. | 2023 | 2 | — |
| +10 | K230766 | Altus Spine Monaco Pedicle Screw System | Altus Spine | 2023 | 1 | — |
| +10 | K223837 | SPIRA®-C Integrated Fixation System | Camber Spine Technologies | 2023 | 0 | — |
| +10 | K222107 | Black Diamond™ POCT Spinal System | Osseus Fusion Systems | 2022 | 0 | — |
| +10 | K222362 | Salvo® Spine System | Spine Wave, Inc. | 2022 | 3 | — |
| +10 | K220782 | IdentiTi™ Porous Ti Interbody System, IdentiTi™ NanoTec™ Interbody System, Transcend™… | Alphatec Spine, Inc. | 2022 | 36 | — |
| +10 | K214006 | Invictus® Spinal Fixation System | Alphatec Spine, Inc. | 2022 | 16 | — |
| +10 | K200896 | Solstice CCI | Life Spine, Inc. | 2020 | 0 | — |
| +10 | K193129 | Yukon OCT Spinal System | K2m, Inc. | 2020 | 0 | 1 |
| +10 | K183381 | Navigation Enabled Instruments | Stryker | 2019 | 1 | — |
| +11 | K261882 | Pisces-SC Standalone Cervical Interbody System | Osseus Fusions Systems, LLC | 2026 | 0 | — |
| +11 | K261205 | SPINEART Navigation Instrument System | Spineart SA | 2026 | 0 | — |
| +11 | K262094 | E3D™-C Interbody System | Evolution Spine | 2026 | 0 | — |
| +11 | K260036 | NeckTune™ 3D SA Cervical Cage | Medyssey Co, Ltd. | 2026 | 0 | — |
| +11 | K254247 | Osteomni Spinal Fixation System | Osteomni, Inc. | 2026 | 0 | — |
| +11 | K254105 | Hive™ Standalone Cervical System and Hive™ C Interbody System | NanoHive Medical, LLC | 2026 | 0 | — |
| +11 | K260038 | E3D™-C Interbody System | Evolution Spine | 2026 | 1 | — |
| +11 | K252894 | aprevo® cervical interbody system | Carlsmed, Inc. | 2026 | 1 | — |
| +11 | K243802 | aprevo® anterior and lateral lumbar interbody fusion device, aprevo® anterior lumbar… | Carlsmed, Inc. | 2025 | 3 | — |
| +11 | K242260 | aprevo® Cervical ACDF; aprevo® Cervical ACDF-X; aprevo® Cervical ACDF-X NO CAM | Carlsmed, Inc. | 2024 | 3 | — |
| +11 | K240685 | Salvo® Spine System | Spine Wave, Inc. | 2024 | 2 | — |
| +11 | K232432 | E3D™-A Interbody System | Evolution Spine | 2024 | 8 | — |
| +11 | K223513 | UniVy™ OsteoVy™-Ti Cervical IBF System | Vy Spine, LLC | 2023 | 1 | — |
| +11 | K222973 | IdentiTi and Transcend Interbody Systems: IndentiTi Cervical Porous Ti Interbody System… | Alphatec Spine, Inc. | 2022 | 13 | — |
| +11 | K222028 | IdentiTi™ Porous Ti Interbody System, IdentiTi™ NanoTec™ Interbody System, Transcend™… | Alphatec Spine | 2022 | 28 | — |
| +12 | K260286 | Dynamo™ Spinal Cement; Salvo® Spine System | Spine Wave, Inc. | 2026 | 0 | — |
| +12 | K260385 | aprevo® anterior and lateral lumbar interbody system; aprevo® posterior and… | Carlsmed, Inc. | 2026 | 0 | — |
| +12 | K250827 | aprevo® anterior lumbar interbody fusion device; aprevo® lateral lumbar interbody fusion… | Carlsmed, Inc. | 2025 | 2 | — |
| +12 | K241783 | FortiVy™ OsteoVy™ Lumbar IBF | Vy Spine, LLC | 2025 | 0 | — |
| +12 | K241375 | IdentiTi Porous Ti Interbody System; IdentiTi NanoTec Interbody System; IdentiTi… | Alphatec Spine | 2025 | 3 | — |
| +12 | K242147 | Calibrate LTX Interbody System; Calibrate NanoTec LTX Interbody System | Alphatec Spine, Inc. | 2024 | 1 | — |
| +12 | K240368 | E3D™-A Interbody System | Evolution Spine | 2024 | 7 | — |
| +12 | K233640 | Segmental Plating System (SPS);IdentiTi SPS Interbody System;IdentiTi NanoTec SPS… | Alphatec Spine, Inc. | 2024 | 5 | — |
| +12 | K232504 | Calibrate CCX Interbody System | Alphatec Spine, Inc. | 2023 | 1 | 1 |
| +12 | K232097 | IdentiTi ALIF Interbody Systems | Alphatec Spine, Inc. | 2023 | 7 | 1 |
| +12 | K231438 | Calibrate PSX Interbody System, Calibrate NanoTec PSX Interbody System | Alphatec Spine, Inc. | 2023 | 7 | — |
| +12 | K223611 | Calibrate LTX Interbody System | Alphatec Spine, Inc. | 2023 | 7 | — |