Devices descending from K022285
403 later devices reach Modification to Isola Spinal System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K191212 | CrossOver Cross Connectors, DePuy PULSE Thoracolumbar Screw System, EXPEDIUM Fenestrated… | Medos International SARL | 2019 | 0 | — |
| +1 | K133746 | Polaris Spinal System | Biomet Spine (Aka Ebi, LLC) | 2014 | 67 | 1 |
| +1 | K120291 | OP Spine System | OrthoPediatrics Corp. | 2012 | 138 | — |
| +1 | K110896 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2012 | 5 | — |
| +1 | K101112 | Reliance Spinal Screw System | Reliance Medical Systems | 2010 | 7 | — |
| +1 | K081978 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2009 | 8 | — |
| +1 | K073126 | Expedium Spine System | Depuy Spine, Inc. | 2007 | 304 | — |
| +2 | K243249 | TriALTIS™ Spine System | Medos International SARL | 2025 | 0 | — |
| +2 | K213750 | VyLink™ Spinal Screw System | Vy Spine, LLC | 2022 | 1 | — |
| +2 | K162134 | ENNOVATE Spinal System | Aesculap Implant Systems, LLC | 2016 | 2 | — |
| +2 | K162066 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2016 | 3 | — |
| +2 | K151974 | Polaris Spinal System | Biomet Spine | 2015 | 16 | — |
| +2 | K152131 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2015 | 4 | — |
| +2 | K150896 | Vitality Spinal Fixation System | Zimmer Spine, Inc. | 2015 | 19 | 3 |
| +2 | K151422 | Reform Pedicle Screw System | Precision Spine, Inc. | 2015 | 19 | — |
| +2 | K150600 | Response 5.5/6.0 Spine System | OrthoPediatrics Corp. | 2015 | 16 | 3 |
| +2 | K141695 | Acrosspine Pedicle Screw System | Arthro-Dif | 2014 | 0 | — |
| +2 | K143248 | Reform Pedicle Screw System | Precision Spine, Inc. | 2014 | 30 | — |
| +2 | K130655 | Response Spine System | OrthoPediatrics Corp. | 2013 | 17 | — |
| +2 | K130291 | S4 Spinal System | Aesculap Implant System, Inc. | 2013 | 44 | — |
| +2 | K123521 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2013 | 5 | — |
| +2 | K123352 | S4 Spinal System | Aesculap Implant Systems, Inc. | 2012 | 51 | — |
| +2 | K121630 | Range Spinal System | K2m, Inc. | 2012 | 127 | — |
| +2 | K121250 | OP Spine System | OrthoPediatrics Corp. | 2012 | 18 | — |
| +2 | K090799 | Modification to Expedium Spine System | Depuy Spine, Inc. | 2009 | 4 | — |
| +2 | K081898 | Expedium Spine System | Depuy Spine, Inc. | 2008 | 59 | — |
| +2 | K082195 | Modifications to Expedium Spine System | Depuy Spine, Inc. | 2008 | 269 | — |
| +3 | K243106 | CarboClear® Hybrid Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2024 | 0 | — |
| +3 | K230325 | GREENS BRAND Posterior, Non-cervical Pedicle Screw Spinal System | Greens Surgicals Pvt., Ltd. | 2024 | 0 | — |
| +3 | K233793 | CarboClear® X Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2024 | 1 | — |
| +3 | K233944 | CarboClear® X Pedicle Screw System; CarboClear® X Navigated Instruments | CarboFix Orthopedics, Ltd. | 2024 | 3 | — |
| +3 | K231744 | VyLink™ Spinal Screw System | Vy Spine, LLC | 2023 | 0 | — |
| +3 | K232341 | CarboClear® Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2023 | 4 | — |
| +3 | K210963 | ENNOVATE Spinal System | Aesculap Implant Systems, LLC | 2021 | 0 | — |
| +3 | K210874 | Reliance Spinal Screw System | Reliance Medical Systems, LLC | 2021 | 2 | — |
| +3 | K210716 | CarboClear X Pedicle Screw System, CarboClear X Navigated Instruments | CarboFix Orthopedics, Ltd. | 2021 | 8 | — |
| +3 | K210275 | Polaris Spinal System | Zimmer Biomet Spine, Inc. | 2021 | 0 | — |
| +3 | K203317 | CarboClear X Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2020 | 9 | — |
| +3 | K200303 | Reform Pedicle Screw System | Precision Spine | 2020 | 10 | — |
| +3 | K200519 | CarboClear® II Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2020 | 11 | — |
| +3 | K193100 | RESPONSE™ Spine System, RESPONSE™ 4.5/5.0 Spine System, RESPONSE™ 5.5/6.0 Spine System | OrthoPediatrics Corp. | 2020 | 4 | — |
| +3 | K193396 | PERLA® TL posterior osteosynthesis system | Spineart | 2020 | 7 | 2 |
| +3 | K192121 | Black Diamond Pedicle Screw System | Osseus Fusion Systems | 2019 | 13 | — |
| +3 | K182974 | NuVasive Reline System | Nu Vasive, Incorporated | 2019 | 11 | — |
| +3 | K182377 | CarboClear® Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2018 | 39 | — |
| +3 | K181390 | Response Spine System, Response 5.5/6.0 Spine System, Response 4.5/5.0 Spine System | OrthoPediatrics Corp. | 2018 | 13 | — |
| +3 | K180433 | Ennovate® | Aesculap Implant Systems, LLC | 2018 | 1 | 1 |
| +3 | K172101 | ROMEO® 2 Posterior Osteosynthesis System | Spineart | 2017 | 9 | — |
| +3 | K171832 | Range/Denali/Mesa Spinal System | K2m, Inc. | 2017 | 13 | — |
| +3 | K170861 | Premier | Shandong Weigao Orthopaedic Device Co., Ltd. | 2017 | 0 | — |
| +3 | K171907 | Vitality® Spinal Fixation System | Zimmer Biomet Spine, Inc. | 2017 | 16 | 2 |
| +3 | K170266 | Palisade™ Pedicular Fixation System | Spineology, Inc. | 2017 | 2 | — |
| +3 | K170255 | Threshold™ V2 Pedicular Fixation System | Spineology, Inc. | 2017 | 1 | — |
| +3 | K170251 | Threshold™ Pedicular Fixation System | Spineology, Inc. | 2017 | 1 | — |
| +3 | K170268 | Fortress™ Pedicular Fixation System | Spineology, Inc. | 2017 | 1 | — |
| +3 | K161028 | K2M Growing Spine System | K2m, Inc. | 2016 | 3 | — |
| +3 | K160124 | LUMIS Cannulated Pedicle Screw Fixation System, U.L.I.S. Pedicle Screw Fixation System | Spinevision S.A. | 2016 | 2 | — |
| +3 | K160466 | Response 5.5 Spine System | OrthoPediatrics Corp. | 2016 | 1 | — |
| +3 | K150856 | Reform Pedicle Screw System | Precision Spine, Inc. | 2015 | 26 | — |
| +3 | K141873 | Range/Mesa/Denali Spinal System | K2m, Inc. | 2014 | 30 | — |
| +3 | K140765 | Range/Mesa/Denali Spinal System | K2m, Inc. | 2014 | 15 | — |
| +3 | K133575 | Spinevision Lumis Cannulated Pedicle Screw Fixation System, Spinevision U.L.I.S. Pedicle… | Spinevision S.A. | 2014 | 3 | — |
| +3 | K141147 | Range Spinal System | K2m, Inc. | 2014 | 1 | — |
| +3 | K133944 | Range, Spinal System, Everest Spinal System | K2m, Inc. | 2014 | 33 | — |
| +3 | K132757 | Everest Spinal System | K2m, Inc. | 2013 | 41 | — |
| +3 | K131784 | Range Spinal System | K2m, Inc. | 2013 | 34 | — |
| +3 | K130932 | Firebird Spinal Fixation System | Orthofix, Inc. | 2013 | 81 | 1 |
| +3 | K122877 | Range Spinal System, Small Stature | K2m, Inc. | 2013 | 34 | — |
| +3 | K130330 | Range Spinal System | K2m, Inc. | 2013 | 36 | — |
| +3 | K123412 | Range Spinal System, Small Strature Components | K2m, Inc. | 2013 | 34 | — |
| +3 | K113396 | Depuy Pulse Thoracolumbar Screw System | Medos International SARL | 2012 | 1 | — |
| +3 | K110216 | Expedium System, Viper System | Depuy Spine, Inc. | 2011 | 4 | — |
| +3 | K103133 | Veper System, Expedium System | Depuy Spine, Inc. | 2011 | 0 | — |
| +3 | K092473 | Expedium Spine System | Depuy Spine, Inc. | 2009 | 263 | — |
| +4 | K253966 | PERLA® TL Posterior Thoraco-lumbar Fixation System | Spineart SA | 2026 | 0 | — |
| +4 | K253545 | Vulcan Spinal System | K2m, Inc. | 2026 | 0 | — |
| +4 | K242827 | A8 INTEGR8™ Porous Pedicle Screws | Allumin8, Inc. | 2025 | 1 | — |
| +4 | K251719 | Momentum® Posterior Spinal Fixation System | Ulrich Medical USA, Inc. | 2025 | 0 | — |
| +4 | K242297 | Reform Pedicle Screw System | Precision Spine, Inc. | 2024 | 0 | — |
| +4 | K242764 | MediRod Pedicle Screw System | Cmf Medicon Surgical, Inc. | 2024 | 0 | — |
| +4 | K242361 | OZARK Cervical Plate System; PYRENEES® Cervical Plate System; EVEREST® Spinal System… | Stryker Spine | 2024 | 1 | — |
| +4 | K240180 | Orthopeasia Spinal Fixation System | Orthopeasia Co., Ltd. | 2024 | 0 | — |
| +4 | K241519 | Invictus® Small Stature Spinal Fixation System | Alphatec Spine, Inc. | 2024 | 2 | — |
| +4 | K240846 | CarboClear® Hybrid Pedicle Screw System; CarboClear® Hybrid Navigated Instruments… | CarboFix Orthopedics, Ltd. | 2024 | 2 | — |
| +4 | K233989 | CarboClear® Posterior Cervical Screw System | CarboFix Orthopedics, Ltd. | 2024 | 2 | — |
| +4 | K231069 | PERLA® TL Posterior Thoraco-lumbar Fixation System | Spineart SA | 2023 | 1 | — |
| +4 | K231280 | CarboClear® X Pedicle Screw System; CarboClear® X Navigated Instruments; CarboClear® X… | CarboFix Orthopedics, Ltd. | 2023 | 4 | — |
| +4 | K222105 | RESPONSE 5.5/6.0 Cannulated Screw System | OrthoPediatrics Corp. | 2023 | 0 | — |
| +4 | K220862 | E-GPS Navigated Instruments | Precision Spine, Inc. | 2022 | 7 | — |
| +4 | K213935 | PISCES-SA Standalone ALIF Interbody System | Osseus Fusion Systems | 2022 | 12 | — |
| +4 | K220025 | ARx® Spinal System | Life Spine, Inc. | 2022 | 0 | — |
| +4 | K213470 | PERLA® TL Posterior Osteosynthesis System | Spineart | 2022 | 2 | — |
| +4 | K210539 | CoreLink Midline Fixation System | Corelink, LLC | 2021 | 4 | — |
| +4 | K201420 | Republic Spine Dark Star Spinal System | Republic Spine, LLC | 2021 | 2 | — |
| +4 | K203506 | PERLA® TL posterior osteosynthesis system | Spineart | 2021 | 3 | 2 |
| +4 | K203222 | PERLA TL Posterior Osteosynthesis System | Spineart | 2020 | 4 | — |
| +4 | K200596 | G21 Cement, VADER® Pedicle System | Icotec AG | 2020 | 27 | 1 |
| +4 | K201926 | CarboClear® Pedicle Screw System, CarboClear® II Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2020 | 10 | — |
| +4 | K201251 | CarboClear Navigated Instruments | CarboFix Orthopedics, Ltd. | 2020 | 9 | — |
| +4 | K193423 | VADER®one Pedicle System MIS and LightMore® Pedicle System 6.0 | Icotec AG | 2020 | 6 | 1 |