Devices descending from K921251
304 later devices reach Cusa System 200C and 200T Ultrasonic Aspirator through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K991791 | Sound Vaser System | Sound Surgical Technologies, LLC | 1999 | 49 | 2 |
| +1 | K981262 | Cusa Excel Ultrasonic Surgical Aspirator System | Valleylab, Inc. | 1998 | 89 | 3 |
| +1 | K962952 | Olympus Ultrasonic Surgical System (Usu) | Olympus Optical, Co. | 1996 | 214 | — |
| +1 | K960040 | Sharplan Ultra Laparoscopic Handpiece | Sharplan Lasers, Inc. | 1996 | 0 | — |
| +2 | K141674 | Cusa Excel+ Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2014 | 0 | 1 |
| +2 | K141668 | Cusa Excel+ Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2014 | 14 | — |
| +2 | K102258 | Cusa NXT Extended Length Tip | Integra Radionics, Inc. | 2011 | 2 | — |
| +2 | K090864 | Cusa Shear Tip, an Accessory of the Cusa Excel Ultrasonic Surgical Aspirator System | Integra Radionics, Inc. | 2009 | 0 | — |
| +2 | K051947 | Radionics Cusa Excel Ultrasonic Surgical Aspirator System with Bone | Radionics, A Division of Tyco Healthcare Group LP | 2005 | 29 | — |
| +2 | K042277 | Selector Quantum Ultrasonic Aspirator System | Integra Neurosciences, Ltd. | 2004 | 17 | — |
| +2 | K041566 | Sonosurg Ultrasonic Surgical System | Aomori Olympus Co., Ltd. | 2004 | 0 | — |
| +2 | K032066 | Sonosurg System | The Olympus Optical Co. | 2003 | 1 | — |
| +2 | K021989 | Selector Integra Ultrasonic Surgical Aspirator, Model OM 1530000M3 | Integra Neurosciences | 2002 | 23 | 2 |
| +2 | K022051 | Soundvaser System | Sound Surgical Technologies, LLC | 2002 | 48 | 2 |
| +2 | K993628 | Omnisonics Ultrasonic Probes | Omnisonics Medical Technologies | 1999 | 0 | — |
| +2 | K972114 | Olympus Sonosurg System | The Olympus Optical Co. | 1998 | 213 | — |
| +3 | K221763 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2022 | 0 | — |
| +3 | K190180 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2019 | 1 | — |
| +3 | K182809 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2018 | 10 | 42 |
| +3 | K161882 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2016 | 11 | 2 |
| +3 | K150682 | CUSA Excel+ | Integra Lifesciences Corp. | 2015 | 1 | — |
| +3 | K113128 | Microaire Surgical Instruments LLC | Microaire Surgical Instruments, LLC | 2012 | 1 | 2 |
| +3 | K111741 | Integra (TM) Cusa NXT (TM) Bone Tips | Integra Burlington Ma, Inc. (Formerly Integra Radi | 2011 | 1 | — |
| +3 | K110306 | Sound Surgical Vaser 2.1 Lipo System | Sound Surgical Technologies, LLC | 2011 | 5 | 1 |
| +3 | K101561 | TX1 Tissue Removal System | American Optisurgical, Inc. | 2010 | 3 | 2 |
| +3 | K081459 | Cusa Selector NXT Ultrasonic Tissue Ablation System | Integra Radionics, Inc. | 2008 | 16 | 4 |
| +3 | K071669 | Integra Selector Ultrasonic Surgical Aspirator System with Bone Tip | Integra Radionics, Inc. | 2007 | 17 | — |
| +3 | K062471 | Ultrasonic Surgical Aspirator System, Model FS 1000 RF | Misonix, Inc. | 2006 | 6 | — |
| +3 | K050885 | Olympus Ultrasonic Surgical System Sonosurg | Olympus Medical Systems Corporation | 2005 | 15 | — |
| +3 | K042261 | Macropore Puricel Lipoplasty System | Macropore Biosurgery, Inc. | 2004 | 36 | — |
| +3 | K041058 | Misonix Inc. Lysonix 2000/3000 Ultrasonic Surgical Aspirator Systems | Misonix, Inc. | 2004 | 4 | 1 |
| +3 | K030598 | Medisiss Reprocessed Ultrasonic Surgical Instruments | Medisiss | 2004 | 0 | — |
| +3 | K031523 | Olympus Ultrasonic Surgical System | Aomori Olympus Co., Ltd. | 2003 | 18 | — |
| +3 | K031305 | Olympus Ultrasonic Surgical System | Olympus Optical Co., Ltd. | 2003 | 26 | — |
| +3 | K031710 | Olympus Ultrasonic Surgical System | Aomori Olympus Co., Ltd. | 2003 | 18 | — |
| +3 | K021962 | Olympus Ultrasonic Surgical System | The Olympus Optical Co. | 2003 | 19 | — |
| +3 | K021929 | Axya Medical, Inc, Model 100 Sonic Scalpel Ultrasonic Surgical System | Axya Medical, Inc. | 2002 | 0 | — |
| +3 | K981993 | Olympus Integrated Endosurgery System Endoalpha | The Olympus Optical Co. | 1998 | 175 | — |
| +4 | K251162 | CUSA® Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2025 | 0 | — |
| +4 | K244050 | AYON Body Contouring System (AYON SYSTEM) | Apyx Medical Corporation | 2025 | 1 | — |
| +4 | K240493 | CUSA® Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2024 | 0 | — |
| +4 | K230427 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2023 | 0 | — |
| +4 | K202299 | Ultrasonic Surgical Aspirator System | Smtp Technology Co., Ltd. | 2021 | 1 | — |
| +4 | K200774 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2020 | 5 | — |
| +4 | K190160 | neXus Ultrasonic Surgical Aspirator System | Misonix, Inc. | 2019 | 1 | — |
| +4 | K190551 | VASERlipo System | Solta Medical | 2019 | 2 | — |
| +4 | K181367 | Tenex Health TX System with the TXP MicroTip | Tenex Health, Inc. | 2018 | 1 | — |
| +4 | K172595 | CUSA Excel+ Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2017 | 0 | — |
| +4 | K171242 | Alma LipoFlow System | Alma Lasers, Inc. | 2017 | 0 | — |
| +4 | K123640 | TX1 Tissue Removal System | Tenex Health | 2013 | 2 | 1 |
| +4 | K121550 | Harmonic Ace Laparoscopic 5MM Diameter Shears 36CM Length + Adaptive Tissue Technology | Ethicon Endo-Surgery, LLC | 2012 | 2 | 2 |
| +4 | K113570 | Integra Cusa NXT Inferior Foward Bone Tip | Integra Burlington Ma, Inc. | 2012 | 0 | — |
| +4 | K111202 | Surgical Tissue Management System | Olympus Medical Systems Corp. | 2012 | 11 | 10 |
| +4 | K092066 | Phaser Lipoplasty System (Dur-01), Phaser Disposable Kit (Dis-01), Phaser Waste… | Andrew Technologies, LLC | 2010 | 2 | — |
| +4 | K100597 | Harmonic Focus Shears | Ethicon Endo-Surgery, LLC | 2010 | 18 | — |
| +4 | K083455 | Lipokit with Disposable 50CC Aft Syringe, Model ZLK-100 | Medi-Khan USA, Inc. | 2009 | 5 | — |
| +4 | K072587 | Cytori Aft System | Cytori Therapeutics, Inc. | 2007 | 34 | — |
| +4 | K063235 | Cytori Lipoplasty System with Celase Reagent | Cytori Therapeutics, Inc. | 2007 | 0 | — |
| +4 | K050209 | Smith & Nephew Control Digital Operating Room System | Smith & Nephew, Inc. | 2005 | 3 | — |
| +4 | K052183 | Soring GMBH Sonoca Lipo | Soring GmbH Medizintechnik | 2005 | 3 | — |
| +4 | K050829 | Nurse's Assistant 1.7 O.R. Control System | Conmed Integrated Systems (Cmis) | 2005 | 3 | — |
| +4 | K042160 | Sonosurg Trocar | Aomori Olympus Co., Ltd. | 2005 | 0 | — |
| +4 | K020255 | Riwo Net Operating Operating Control System, Model #5590 | Richard Wolf Medical Instruments Corp. | 2002 | 1 | — |
| +4 | K022270 | Modification to Olympus Integrated Endosurgery System Endoalpha | Olympus Optical Co., Ltd. | 2002 | 8 | — |
| +4 | K994231 | Siemens Integrated Operating System (Sios) | Siemens Medical Corp. | 2000 | 157 | — |
| +5 | K254135 | LipoSurg ARTIST | Nouvag AG | 2026 | 0 | — |
| +5 | K241700 | Tenex 2nd Generation System | Trice Medical, Inc. | 2024 | 0 | — |
| +5 | K212969 | Liposaver | Lhbiomed Co., Ltd. | 2024 | 1 | — |
| +5 | K221835 | CUSA Clarity Ultrasonic Surgical Aspirator System | Integra LifeSciences Corporation | 2022 | 0 | — |
| +5 | K221235 | neXus Ultrasonic Surgical Aspirator System | Misonix, Inc. | 2022 | 2 | — |
| +5 | K212060 | neXus Ultrasonic Surgical Aspirator System | Misonix, Inc. | 2021 | 0 | — |
| +5 | K212750 | Ultrasonic Surgical Aspirator System, Model: XD880B | Smtp Technology Co., Ltd. | 2021 | 0 | — |
| +5 | K211838 | Ultrasonic Bipolar Generator USG-410 with accessories | Olympus Medical Systems Corporation | 2021 | 3 | 13 |
| +5 | K172691 | Ultrasonic Generator | Olympus Medical Systems Corp. | 2017 | 4 | — |
| +5 | K161086 | Reprocessed Harmonic Shears with Adaptive Tissue Technology (36 cm), Reprocessed… | Sterilmed, Inc. | 2016 | 0 | — |
| +5 | K153299 | Tenex Health TX System | Tenex Health, Inc. | 2016 | 1 | — |
| +5 | K151743 | THUNDERBEAT Open Fine Jaw | Olympus Medical Systems Corp. | 2016 | 6 | — |
| +5 | K151282 | core nova Complete Operating Room Endoscopy | Richard Wolf Medical Instruments Corp. | 2016 | 0 | — |
| +5 | K132566 | Reprocessed Harmonic Shear | Sterilmed, Inc. | 2014 | 0 | — |
| +5 | K132703 | Thunderbeat | Olympus Medical Systems Corp. | 2014 | 9 | — |
| +5 | K124033 | Medisiss Reprocessed Ultrasonic Instruments | Surgical Instruments Service and Savings, Inc. | 2014 | 0 | — |
| +5 | K133314 | Harmonic Focus Shears + Adaptive Tissue Technology | Ethicon Endo-Surgery, LLC | 2013 | 9 | — |
| +5 | K121218 | Hydrasolve Console Sterile Treatment Kit Reusable Cannula, 4MM Dia, 26 CM Length, 3… | Andrew Technologies, LLC | 2012 | 1 | — |
| +5 | K121703 | Lipokit with Disposable 50CC Aft Syringe | Medi-Khan USA, Inc. | 2012 | 0 | — |
| +5 | K100114 | Fat Concentration System | Biomet, Inc. | 2010 | 8 | — |
| +5 | K101713 | Lipcollector II | Human Med AG | 2010 | 3 | — |
| +5 | K092923 | Cytori Puregraft 250/Pure System | Cytori Therapeutics, Inc. | 2010 | 2 | — |
| +5 | K092482 | Tissu Trans Filtron, Models 3-TT-Filtron 2000-500 | Shippert Medical Technologies Corp. | 2009 | 17 | 8 |
| +5 | K081848 | Lipose Fat Transfer System | Lipose Corp. | 2008 | 12 | — |
| +5 | K070556 | Brainsuite Net | Brainlab AG | 2007 | 2 | — |
| +5 | K060717 | Nurse Assistant 1.7 O.R. Control System | Conmed Integrated Systems (Cmis) | 2006 | 1 | — |
| +5 | K052202 | Axiom Artis - Modular Angiographic System | Siemens Medical Solutions USA, Inc. | 2006 | 154 | 29 |
| +5 | K052740 | Nurse's Assistant 1.7 O.R. Control System | Conmed Integrated Systems (Cmis) | 2005 | 2 | — |
| +5 | K041494 | Olympus Integrated Endosurgery System Endoalpha (Control Unit for Endosurgery Uces-2)… | Olympus Corporation | 2004 | 6 | — |
| +5 | K031979 | Conmed Integrated Systems Nurses Assistant | Conmed Integrated Systems (Cmis) | 2003 | 0 | — |
| +6 | K254056 | THUNDERBEAT 5 mm, 45 cm, Front-actuated Grip Type S (TB-0545FCS); THUNDERBEAT 5 mm, 35… | Olympus Medical Systems Corp. | 2026 | 0 | — |
| +6 | K252495 | Lssa (NP-200) | Newpong Co., Ltd. | 2026 | 0 | — |
| +6 | K252150 | Ultrasonic Bipolar Generator (USG-410); Reuseable Cordless Transducer (TD-410)… | Olympus Medical Systems Corporation | 2025 | 0 | 4 |
| +6 | K231777 | Electrosurgical Generator ESG-410 and Accessories (WA91327U, WA91327W), Accessories… | Olympus Winter & Ibe GmbH | 2023 | 0 | 2 |
| +6 | K231117 | neXus Ultrasonic Surgical Aspirator System | Misonix, LLC, A Bioventus Company | 2023 | 1 | — |