Devices descending from K990131
224 later devices reach Pro Osteon Implant 500R Resorbable Bone Graft Substitute through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +3 | K091031 | Pioneer Surgical Nanoss BVF-E | Pioneer Surgical Technology | 2009 | 7 | — |
| +3 | K090850 | Actifuse Bone Graft Substitute, Actifuse Microgranules Bone Graft Substitute | Apatech, Ltd. | 2009 | 0 | 1 |
| +3 | K083449 | E-Matrix Graft Bone Extender | Pioneer Surgical Technology | 2009 | 0 | — |
| +3 | K082166 | Mastergraft Strip | Medtronic Sofamor Danek | 2009 | 38 | — |
| +3 | K082419 | Reoss Powder, Reoss Putty, Reoss Gel, Models R-1,RP-1, RG-1 | Intra-Lock International, Inc. | 2009 | 2 | — |
| +3 | K082286 | Bioactys | Graftys | 2009 | 1 | — |
| +3 | K090177 | Inion Biorestore Biodegradable Bone Graft Substitute | Inion OY | 2009 | 2 | — |
| +3 | K081717 | Tricos a Resorbable Bone Substitute | Baxter Healthcare Corp | 2008 | 0 | — |
| +3 | K081784 | Mastergraft Putty | Medtronic Sofamor Danek | 2008 | 1 | — |
| +3 | K081721 | Tricos a Resorbable Substitute | Baxter Healthcare Corp | 2008 | 0 | — |
| +3 | K080772 | Bonemedik-DM | Meta Biomed Co., Ltd. | 2008 | 0 | — |
| +3 | K073571 | Tricos T Resorbable Bone Substitute | Baxter Healthcare Corporation | 2008 | 2 | — |
| +3 | K073064 | Graftys BCP | Graftys | 2008 | 2 | — |
| +3 | K071187 | Microfuse Bone Void Filler | Globus Medical, Inc. | 2007 | 4 | — |
| +3 | K071912 | Apaceram Bone Graft Substitute | Pentax Corp. | 2007 | 1 | — |
| +3 | K072384 | Modification to Copios Bone Void Filler Sponge & Paste | Kensey Nash Corp. | 2007 | 0 | — |
| +3 | K071121 | Tribone 80 | Biomatlante | 2007 | 0 | — |
| +3 | K063527 | MBCP+ | Biomatlante | 2007 | 0 | 1 |
| +3 | K070794 | Atlantik | Medical Biomat | 2007 | 0 | — |
| +3 | K062834 | Osteon, Models GBG0305, GBG0510, GBG1020, GBG2030, GBG3040, GBG4050 | Genoss Co., Ltd. | 2007 | 5 | — |
| +3 | K060732 | MBCP Gel | Biomatlante | 2006 | 40 | — |
| +3 | K050806 | Optecure | Exactech, Inc. | 2006 | 3 | — |
| +4 | K253147 | FIBERGRAFT™ BG Putty GPS Bone Graft Substitute FIBERGRAFT™ BG Putty Bone Graft… | Prosidyan, Inc. | 2025 | 0 | — |
| +4 | K251556 | Device 300423 Granules | Geistlich Pharma AG | 2025 | 0 | — |
| +4 | K243949 | OsteoFlo HydroFiber | SurGenTec, LLC | 2025 | 0 | — |
| +4 | K242797 | OsteoFlo HydroFiber | SurGenTec, LLC | 2024 | 1 | — |
| +4 | K240765 | Porous Biologic Scaffold | Ventris Medical | 2024 | 0 | — |
| +4 | K240507 | NuVasive AttraX Scaffold | Nuvasive, Inc. | 2024 | 0 | — |
| +4 | K230736 | MagnetOs Putty | Kuros Biosciences B.V | 2023 | 4 | — |
| +4 | K231968 | Tactoset® Injectable Bone Substitute | Anika Therapeutics, Inc. | 2023 | 0 | — |
| +4 | K233607 | MagnetOs Easypack Putty | Kuros Biosciences B.V | 2023 | 2 | — |
| +4 | K231030 | Cove Putty, OsteoCove Putty | SeaSpine Orthopedics Corporation | 2023 | 0 | — |
| +4 | K230486 | Cove Strip | SeaSpine Orthopedics Corporation | 2023 | 1 | — |
| +4 | K213260 | CMFlexTM | Dimension Inx Corp. | 2022 | 0 | — |
| +4 | K221644 | Synthetic Bone Putty | Ventris Medical | 2022 | 0 | — |
| +4 | K213803 | FIBERGRAFT Aeridyan Matrix Bone Graft Substitute | Prosidyan, Inc. | 2022 | 1 | — |
| +4 | K212991 | Osteorevive | Bone Solutions, Inc. | 2022 | 1 | — |
| +4 | K212156 | ABCcolla Bone Matrix | Acro Biomedical Co., Ltd. | 2021 | 0 | — |
| +4 | K193513 | SIGNAFUSE Bioactive Bone Graft | Bioventus | 2020 | 0 | — |
| +4 | K193075 | Osteo3 ZP Putty | Sirakoss, Ltd. | 2020 | 4 | — |
| +4 | K200640 | Altapore Shape | Baxter Healthcare Corporation | 2020 | 1 | — |
| +4 | K192363 | Altapore | Baxter Healthcare Corporation | 2020 | 4 | — |
| +4 | K191513 | Altapore Shape | Baxter Healthcare Corporation | 2019 | 2 | — |
| +4 | K191074 | Sorrento Bone Graft Substitute | Xenco Medical, LLC | 2019 | 0 | — |
| +4 | K190110 | NanoBone SBX PUTTY, NanoBone QD | Artoss GmbH | 2019 | 0 | — |
| +4 | K182074 | Mineral Collagen Composite Bioactive Moldable | Collagen Matrix, Inc. | 2019 | 3 | — |
| +4 | K182670 | FIBERGRAFT AERIDYAN Matrix Bone Graft Substitute | Prosidyan, Inc. | 2018 | 0 | — |
| +4 | K181721 | Ceracell Ortho Foam | Curasan AG | 2018 | 0 | — |
| +4 | K181225 | Altapore | Baxter Healthcare Corporation | 2018 | 6 | — |
| +4 | K173525 | NovoGro | Osteonovus, Inc. | 2018 | 0 | — |
| +4 | K172573 | ReBOSSIS85 | Orthorebirth Co., Ltd. | 2017 | 1 | 2 |
| +4 | K151172 | MASTERGRAFT Contain | Medtronic Sofamor Danek USA, Inc. | 2015 | 0 | — |
| +4 | K142463 | Bio2 CLM BG Bioactive Scaffold | Bio2 Technologies, Inc. | 2014 | 1 | — |
| +4 | K141824 | Mastergraft Matrix Ext; Mastergraft Putty, Mastergraft Strip | Medtronic Sofamor Danek, Inc. | 2014 | 0 | — |
| +4 | K140374 | Mastergraft Putty | Medtronic Sofamor Danek USA, Inc. | 2014 | 0 | — |
| +4 | K130335 | Mastergraft Strip; Mastergraft Ultramatrix | Medtronic Sofamor Danek USA, Inc. | 2013 | 2 | — |
| +4 | K121989 | Optecure Bone Void Filler (0.5 CC, 1CC, 2CC, 5CC, 10CC, and 20CC), Optecure + CCC Bone… | Exactech, Inc. | 2012 | 1 | — |
| +4 | K122240 | Bone Plus BCP Eagle Eye | Megagen Implant Co., Ltd. | 2012 | 0 | — |
| +4 | K120602 | Apaceram Bone Graft Substitute | Hoya Corporation | 2012 | 0 | — |
| +4 | K112716 | Osteon II | Genoss Co., Ltd. | 2012 | 1 | — |
| +4 | K111944 | NB3D Bone Void Filler | Pioneer Surgical Technology, Inc. | 2011 | 1 | — |
| +4 | K110561 | Fortross Bone Void Filler | Pioneer Surgical Technology | 2011 | 4 | — |
| +4 | K102392 | Microfuse Putty and Microfuse ST Mis | Globus Medical, Inc. | 2010 | 0 | 1 |
| +4 | K102015 | Osteon, Osteon Sinus, Osteon Lifting | Genoss Co., Ltd. | 2010 | 0 | — |
| +4 | K083232 | Modification to:Microfuse Bone Void Filler | Globus Medical, Inc. | 2008 | 1 | — |
| +4 | K082442 | Modification to Microfuse Bone Void Filler | Globus Medical, Inc. | 2008 | 2 | — |
| +4 | K080917 | Iroot SP | Innovative Bioceramix, Inc. | 2008 | 37 | — |
| +4 | K061668 | Optecure +CCC | Exactech, Inc. | 2006 | 2 | — |
| +5 | K261415 | Injectable Root Canal Sealer (KP-Root SP) | Guilin Kevin Peter Technology Co., Ltd. | 2026 | 0 | — |
| +5 | K251818 | Bontree Plus | Hudens Bio Co., Ltd. | 2026 | 0 | — |
| +5 | K252890 | ZenSeal Pro | Kerr Corporation | 2026 | 0 | — |
| +5 | K241555 | Moldable Bone Void Filler and Moldable Bone Void Filler + CCC | Rti Surgical, Inc. | 2025 | 0 | — |
| +5 | K241564 | Actifuse ABX; Actifuse MIS; Actifuse Shape; ALTAPORE; ALTAPORE SHAPE; ALTAPORE MIS | Baxter Healthcare Corporation | 2024 | 0 | — |
| +5 | K241212 | MagnetOs Easypack Putty | Kuros Biosciences | 2024 | 1 | — |
| +5 | K233259 | Xerosyn | Xerothera, Inc. | 2024 | 0 | — |
| +5 | K240442 | MagnetOs Putty | Kuros Biosciences B.V | 2024 | 3 | — |
| +5 | K240453 | ReBOSSIS | Orthorebirth Co., Ltd. | 2024 | 0 | 2 |
| +5 | K232668 | Cove Strip, OsteoCove Strip | SeaSpine Orthopedics Corporation | 2023 | 0 | — |
| +5 | K231942 | Mineral Collagen Composite Bioactive Extra Moldable | Collagen Matrix, Inc. | 2023 | 1 | — |
| +5 | K231259 | iRoot SP Plus | Innovative Bioceramix, Inc. | 2023 | 0 | — |
| +5 | K221735 | Mineral Collagen Composite Bioactive Moldable | Collagen Matrix, Inc. | 2022 | 2 | — |
| +5 | K221256 | Mg OSTEOINJECT | Bone Solutions, Inc. | 2022 | 0 | — |
| +5 | K212983 | Injectable Root Canal Bioceramic Sealer | Beijing C-Root Dental Medical Devices Co., Ltd. | 2021 | 4 | — |
| +5 | K212283 | BioRoot Flow 0.5g, BioRoot Flow 2g | Septodont | 2021 | 0 | — |
| +5 | K201464 | Altapore MIS | Baxter Healthcare Corporation | 2020 | 1 | — |
| +5 | K190503 | CeraSeal | Meta Biomed Co., Ltd. | 2019 | 2 | — |
| +5 | K181922 | Sonendo Material A | Sonendo, Inc. | 2018 | 0 | — |
| +5 | K170175 | Endoseal Mta | Maruchi | 2018 | 8 | — |
| +5 | K172701 | Bio-C Sealer | Angelus Industria DE Produtos Odontologicos S/A | 2018 | 1 | — |
| +5 | K151876 | Bio2 Fusion Implant System | Bio2 Technologies, Inc. | 2015 | 0 | — |
| +5 | K141600 | Nanoss Bioactive, Nanoss Bioactive Loaded, and Nanoss Bioactive Loaded Kit | Pioneer Surgical Technology, Inc. (Rti Surgical, I | 2014 | 3 | — |
| +5 | K130312 | Iroot FM | Innovative Bioceramix, Inc. | 2014 | 0 | — |
| +5 | K132050 | NB3D Bone Void Filler | Pioneer Surgical Technology, Inc. | 2014 | 0 | 1 |
| +5 | K102867 | Iroot FS | Innovative Bioceramix, Inc. | 2010 | 2 | — |
| +5 | K082943 | Iroot BP, Model Irbp 4609 | Innovative Bioceramix, Inc. | 2009 | 12 | — |
| +6 | K262050 | Vioseal X | Spident Co., Ltd. | 2026 | 0 | — |
| +6 | K262230 | Mg OSTEOREVIVE™;Mg OSTEOCRETE™ | Bone Solutions, Inc. | 2026 | 0 | — |
| +6 | K243474 | MagnetOs MIS | Kuros Biosciences B.V | 2025 | 0 | — |
| +6 | K241977 | Injectable Root Canal Bioceramic Sealer (i-MTA SP) | Longly Biotechnology (Wuhan) Co., Ltd. | 2024 | 0 | — |
| +6 | K240304 | Injectable Root Canal Bioceramic Sealer (NR SP-0.5, NR SP-1, NR SP-2, NR SP-3, NR SP-5) | Enpuno Biotechnology Co., Ltd. | 2024 | 2 | — |