Devices descending from K991581
348 later devices reach Nexgen Complete Knee Solution Legacy Posterior Stabilized (LPS); LPS-Flex… through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K230120 | KeYi Total Knee System | Beijing Keyi Medical Device Technology Co., Ltd. | 2024 | 0 | — |
| +1 | K191192 | SurgTech GENOLL Total Knee System | Surgtech, Inc. | 2019 | 0 | — |
| +1 | K173057 | Zimmer Knee Joint Replacement Prostheses MR Labeling | Zimmer, Inc. | 2018 | 5 | 2 |
| +1 | K131864 | U2 Tibial Baseplate- Cma Type, Tibial Insert and Augment | United Orthopedic Corporation | 2014 | 5 | — |
| +1 | K131310 | GMK Full PE Tibial Components | Medacta International | 2013 | 2 | — |
| +1 | K122500 | Neo PS Knee System | Pipeline Orthopedics | 2013 | 1 | — |
| +1 | K123457 | Balanced Knee System High Flex PS | Ortho Development Corp. | 2013 | 4 | — |
| +1 | K113369 | Zimmer Persona Knee System | Zimmer, Inc. | 2012 | 96 | 39 |
| +1 | K094013 | HLS Kneetec System | Tornier | 2011 | 1 | — |
| +1 | K081023 | Evolis Total Knee System | Medacta International S.A. | 2008 | 78 | 1 |
| +1 | K081127 | Accin Total Knee System | Accelerated Innovation, LLC | 2008 | 25 | 1 |
| +1 | K062768 | Nexgen Complete Knee Solution Legacy Posterior Stabilized Flex Fixed Bearing and… | Zimmer, Inc. | 2006 | 25 | — |
| +1 | K060370 | Nexgen Knee Gender Solutions Female (GSF) Femoral Components | Zimmer, Inc. | 2006 | 197 | 17 |
| +1 | K042515 | Smith & Nephew, Inc. High Performance Knee | Smith & Nephew, Inc. | 2005 | 118 | 3 |
| +1 | K043101 | Nexgen Complete Knee Solution Mis Tibial Components, Locking Screw and Stem Extensions | Zimmer, Inc. | 2005 | 59 | 22 |
| +1 | K042271 | Nexgen Complete Knee Solution LPS-Flex Prolong Highly Crosslinked Polyethylene Articular… | Zimmer, Inc. | 2004 | 16 | 2 |
| +1 | K032295 | Genesis II Posterior Stabilized High Flexion Articular Insert | Smith & Nephew, Inc. | 2003 | 76 | 6 |
| +1 | K023211 | Nexgen Complete Knee Solution Cruciate Retaining (CR)-Flex Femoral Components | Zimmer, Inc. | 2002 | 293 | 6 |
| +1 | K013906 | HLS Noetos System | Tornier | 2002 | 3 | — |
| +2 | K262057 | GMK Extension | Medacta International SA | 2026 | 0 | — |
| +2 | K253161 | Balanced Knee System TriMax Porous Femoral Components | Ortho Development Corp. | 2025 | 0 | — |
| +2 | K230078 | TRAX® CR Total Knee System | Amplitude | 2023 | 0 | — |
| +2 | K230653 | Smith & Nephew, Inc. ANTHEM Total Knee System, Genesis Uni Knee System, JOURNEY BCS and… | Smith & Nephew, Inc. | 2023 | 3 | 1 |
| +2 | K230321 | Persona™ Personalized Knee System | Zimmer, Inc. | 2023 | 0 | — |
| +2 | K221479 | Persona Personalized Knee System | Zimmer, Inc. | 2022 | 8 | — |
| +2 | K222700 | Tibial baseplate, Tibial insert | United Orthopedic Corporation | 2022 | 0 | — |
| +2 | K221939 | Cemented Round Patella with JRNY Pegs | Smith & Nephew, Inc. | 2022 | 0 | — |
| +2 | K211221 | Porous Patella and Porous Tibia Baseplate | Smith & Nephew, Inc. | 2021 | 5 | — |
| +2 | K212129 | Persona® Personalized Knee System | Zimmer Switzerland Manufacturing GmbH | 2021 | 0 | — |
| +2 | K210062 | Mectaplug PE II | Medacta International S.A. | 2021 | 0 | — |
| +2 | K200209 | Persona Personalized Knee System | Zimmer, Inc. | 2020 | 2 | — |
| +2 | K193223 | Persona Personalized Knee System | Zimmer, Inc. | 2020 | 3 | — |
| +2 | K191625 | Persona Revision Knee System | Zimmer, Inc. | 2019 | 1 | 1 |
| +2 | K181947 | Persona Revision Knee System | Zimmer, Inc. | 2018 | 4 | 1 |
| +2 | K172524 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2018 | 15 | — |
| +2 | K170534 | Prolixus Total Knee System | Otis Biotech Co., Ltd. | 2017 | 2 | — |
| +2 | K161705 | U2 Total Knee System E-XPE products | United Orthopedic Corporation | 2017 | 1 | — |
| +2 | K152430 | All Poly Tibial Component | United Orthopedic Corporation | 2016 | 0 | — |
| +2 | K153586 | Arthrex iBalance TKA System | Arthrex, Inc. | 2016 | 1 | — |
| +2 | K152252 | Arthrex iBalance TKA System | Arthrex, Inc. | 2015 | 2 | — |
| +2 | K152382 | Arthrex iBalance TKA System | Arthrex, Inc. | 2015 | 2 | — |
| +2 | K152008 | Physica PS Knee System | Lima Corporate S.P.A. | 2015 | 7 | — |
| +2 | K152169 | Balanced Knee System TriMax CR Femoral Component and E-Vitalize CR and UC Tibial Inserts | Ortho Development Corporation | 2015 | 1 | — |
| +2 | K150829 | U2 Total Knee System- Additional Sizes | United Orthopedic Corporation | 2015 | 3 | — |
| +2 | K142787 | Zimmer Persona Personalized Knee System | Zimmer, Inc. | 2014 | 16 | — |
| +2 | K142388 | Neo Total Knee System | New Era Orthopedics, LLC | 2014 | 0 | — |
| +2 | K142069 | GMK Extension | Medacta International | 2014 | 4 | — |
| +2 | K143047 | Arthrex iBalance Patella Implant, Dome | Arthrex, Inc. | 2014 | 2 | — |
| +2 | K140222 | Saiph Knee System | Matortho | 2014 | 0 | — |
| +2 | K141635 | Arthrex Ibalance Tka System | Arthrex, Inc. | 2014 | 15 | — |
| +2 | K140833 | Itotal Posterior Stabilized (PS) Knee Replacement System | Conformis, Inc. | 2014 | 26 | — |
| +2 | K133854 | Arthrex Ibalance Tka System | Arthrex, Inc. | 2014 | 4 | — |
| +2 | K133737 | Zimmer (R) Persona the Personalized Kee System 14X +30MM Tapered Stem Extension | Zimmer, Inc. | 2014 | 5 | — |
| +2 | K133630 | GMK Short Stem | Medacta International | 2013 | 1 | — |
| +2 | K133342 | Arthrex Ibalance Tka System | Arthrex, Inc. | 2013 | 0 | — |
| +2 | K131337 | Balanced Knee System High Flex Vitamin E PS Tibial Insert and Patella | Ortho Development Corp. | 2013 | 3 | — |
| +2 | K123692 | Pipeline Knee System | Pipeline Orthopedics | 2013 | 0 | — |
| +2 | K123159 | Smith & Newphew, Inc. Disposable Knee Instruments | Smith & Nephew, Inc. | 2013 | 2 | — |
| +2 | K123459 | Zimmer Persona TM Personalized Knee System | Zimmer, Inc. | 2013 | 9 | 10 |
| +2 | K130143 | Persona Natural Tibia Baseplates | Zimmer, Inc. | 2013 | 21 | — |
| +2 | K122975 | GKS Prime Flex CR Total Knee System | Permedica | 2012 | 0 | — |
| +2 | K122745 | Zimmer Persona the Personalized Knee System | Zimmer, Inc. | 2012 | 21 | — |
| +2 | K122765 | Persona Natural Tibia Baseplates | Zimmer, Inc. | 2012 | 25 | 2 |
| +2 | K121771 | Zimmer Persona the Personalized Knee System | Zimmer, Inc. | 2012 | 59 | 2 |
| +2 | K121393 | Smith & Nephew, Inc. Total Knee System Instrumentation | Smith & Nephew, Inc. | 2012 | 5 | 4 |
| +2 | K121416 | GMK Sphere | Medacta International | 2012 | 20 | — |
| +2 | K120790 | GMK - Line Extension | Medacta International | 2012 | 11 | — |
| +2 | K120313 | Neo CR Knee System | Pipeline Orthopedics | 2012 | 3 | — |
| +2 | K113122 | Pipeline CR Primary Knee System | Pipeline Orthopedics | 2012 | 1 | — |
| +2 | K113482 | Journey II Deep Dished Articular Inserts | Smith & Nephew, Inc. | 2012 | 6 | — |
| +2 | K111970 | Kneetec PFJ&HLS Kneetec Patellar Component | Tornier | 2012 | 0 | — |
| +2 | K113571 | GMK Resufacing Patella Size 4 | Medacta International | 2012 | 23 | — |
| +2 | K111711 | Journey II BCS Knee System | Smith & Nephew, Inc. | 2011 | 40 | 3 |
| +2 | K111283 | GMK Revision Hybrid Liners | Medacta International | 2011 | 0 | — |
| +2 | K110837 | Revision Prothesis | Smith & Nephew, Inc. | 2011 | 0 | — |
| +2 | K102367 | Optigen Total Knee System | U&I Corp. | 2010 | 0 | — |
| +2 | K094050 | Itotal CR Knee Replacement System | Conformis, Inc. | 2010 | 41 | — |
| +2 | K101499 | Journey CR Knee System | Smith & Nephew, Inc. | 2010 | 45 | — |
| +2 | K101032 | Cardo Medical Femoral Cement Restrictor, Model 503-MCRX | Cardo Medical, Inc. | 2010 | 0 | — |
| +2 | K092803 | Cardo Medical Align 360 Medialized Patella Component | Cardo Medical Corp. | 2009 | 0 | — |
| +2 | K091014 | Journey BCS Knee System | Smith & Nephew, Inc. | 2009 | 41 | — |
| +2 | K090988 | GMK Total Knee System | Medacta International S.A. | 2009 | 52 | 1 |
| +2 | K091069 | Medacta Bone Screws - Evolis and Versafit | Medacta International S.A. | 2009 | 23 | — |
| +2 | K072619 | Nexgen Complete Knee Solution LPS-Flex and Knee Gender Solutions Female (GSF) Porous… | Zimmer, Inc. | 2007 | 102 | 4 |
| +2 | K071071 | Crosslinked Polyethylene Articular Inserts | Smith & Nephew, Inc. | 2007 | 66 | 5 |
| +2 | K071107 | Gender Solutions Natural-Knee Flex System; Nex Gen Complete Knee Solution CR-Flex Gender… | Zimmer, Inc. | 2007 | 0 | 5 |
| +2 | K070695 | Zimmer Patellofemoral Joint Prosthesis | Zimmer, Inc. | 2007 | 122 | 5 |
| +2 | K070214 | Gender Solutions Natural-Knee Flex System | Zimmer, Inc. | 2007 | 123 | 63 |
| +2 | K041825 | Smith & Nephew Genesis II Deep Flexion Cruciate Retaining Articular Insert | Smith & Nephew, Inc. | 2005 | 75 | — |
| +2 | K031061 | Nexgen Porous, Uncemented Femoral and Tibial Baseplate Components | Zimmer, Inc. | 2003 | 193 | 24 |
| +2 | K032079 | HLS Noetos System | Tornier | 2003 | 0 | — |
| +3 | K261462 | LANDMARK Total Knee System | Smith & Nephew, Inc. | 2026 | 0 | — |
| +3 | K251840 | Zimmer® Persona® Personalized Knee System | Zimmer, Inc. | 2026 | 0 | — |
| +3 | K253592 | Zimmer Biomet Reverse Shoulder Prosthesis (Alliance Humeral Bearings, Identity Humeral… | Zimmer, Inc. | 2026 | 0 | — |
| +3 | K254084 | AETOS Shoulder System - CONCELOC Glenoids | Smith & Nephew, Inc. | 2026 | 0 | — |
| +3 | K253189 | Persona the Personalized Knee System (Persona Porous Plasma Spray PPS Femurs) | Zimmer, Inc. | 2026 | 0 | — |
| +3 | K243724 | Persona® Revision Knee System (Persona Revision SoluTion™ Femoral Components) | Zimmer, Inc. | 2025 | 0 | — |
| +3 | K243574 | Evolution® Total Knee Systems - Kinematic Alignment Instrumentation and Technique | Microport Orthopedics, Inc. | 2025 | 1 | — |
| +3 | K241260 | ACTIFY™ Unicondylar Knee System | Globus Medical, Inc. | 2024 | 0 | — |
| +3 | K242543 | Persona the Personalized Knee System (Persona Ti-Nidium PPS Femurs) | Zimmer, Inc. | 2024 | 0 | — |