Devices descending from K100952
314 later devices reach Modification to Synthes Matrix System through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +3 | K151422 | Reform Pedicle Screw System | Precision Spine, Inc. | 2015 | 19 | — |
| +3 | K151196 | Nautilus Spinal System | Life Spine, Inc. | 2015 | 12 | — |
| +3 | K150184 | Dymaxeon Spine System | Back 2 Basics Direct, LLC | 2015 | 4 | 1 |
| +3 | K142835 | Iliad Pedicle Screw System and Zenius Pedicle Screw System | Medyssey USA, Inc. | 2015 | 5 | — |
| +3 | K143248 | Reform Pedicle Screw System | Precision Spine, Inc. | 2014 | 30 | — |
| +4 | K262067 | iFuse Granite Onyx™ Implant System | SI-BONE, Inc. | 2026 | 0 | — |
| +4 | K261130 | AccelFix Spinal Fixation System | L&K BIOMED Co., Ltd. | 2026 | 0 | — |
| +4 | K254148 | VERTICALE GPS Instruments | Silony Medical GmbH | 2026 | 0 | — |
| +4 | K251780 | iGPS Navigation Instruments | SI-BONE, Inc. | 2025 | 0 | — |
| +4 | K252437 | JAZZ Spinal System | Implanet | 2025 | 0 | — |
| +4 | K251073 | Innovasis Navigation Instruments (Vector G-E Navigation Instruments and the Excella G-E… | Innovasis, Inc. | 2025 | 0 | 1 |
| +4 | K241525 | ExcelsiusXR™ | Globus Medical, Inc. | 2025 | 0 | — |
| +4 | K251719 | Momentum® Posterior Spinal Fixation System | Ulrich Medical USA, Inc. | 2025 | 0 | — |
| +4 | K243326 | Dynamis Robotic Surgical System | LEM Surgical AG | 2025 | 1 | — |
| +4 | K243514 | Salvo® Robotic Navigation Instruments | Spine Wave, Inc. | 2025 | 0 | — |
| +4 | K243814 | NuVasive Pulse System | Globus Medical, Inc. | 2025 | 0 | — |
| +4 | K243671 | ExcelsiusGPS® Instruments | Globus Medical, Inc. | 2024 | 0 | — |
| +4 | K240160 | EGPS Navigated Instruments | Astura Medical | 2024 | 0 | — |
| +4 | K230325 | GREENS BRAND Posterior, Non-cervical Pedicle Screw Spinal System | Greens Surgicals Pvt., Ltd. | 2024 | 0 | — |
| +4 | K241519 | Invictus® Small Stature Spinal Fixation System | Alphatec Spine, Inc. | 2024 | 2 | — |
| +4 | K240721 | ExcelsiusFlex™ | Globus Medical, Inc. | 2024 | 0 | — |
| +4 | K240951 | Invictus Robotic Navigation Instruments | Alphatec Spine | 2024 | 2 | — |
| +4 | K241276 | Vector™ Pedicle Screw System | Innovasis, Inc. | 2024 | 1 | 1 |
| +4 | K240392 | JAZZ Spinal System | Implanet | 2024 | 1 | — |
| +4 | K240568 | DuraPro™ Oscillating System | Globus Medical, Inc. | 2024 | 0 | — |
| +4 | K231850 | QUARTEX® Occipito-Cervico-Thoracic Spinal System ExcelsiusGPS® Instruments | Globus Medical, Inc. | 2024 | 2 | — |
| +4 | K233638 | VERZA™ High Speed Drills | Globus Medical, Inc. | 2024 | 1 | — |
| +4 | K231515 | MySpine Cervical Guides | Medacta International S.A. | 2023 | 0 | — |
| +4 | K231809 | Momentum® Posterior Spinal Fixation System with G21 V-STEADY Bone Cement; Momentum® MIS… | Ulrich Medical USA | 2023 | 1 | — |
| +4 | K232044 | Invictus Robotic Navigation Instruments | Alphatec Spine, Inc. | 2023 | 3 | — |
| +4 | K231098 | LineSider® Spinal System | Integrity Implants, Inc. | 2023 | 3 | — |
| +4 | K231483 | MySpine Unilateral Guides | Medacta International S.A. | 2023 | 0 | — |
| +4 | K223558 | CUVIS-spine | Curexo, Inc. | 2023 | 0 | — |
| +4 | K222229 | Advanced LumFix Spinal Fixation System | CG Bio Co., Ltd. | 2023 | 2 | — |
| +4 | K223350 | Remi Robotic Navigation System | Fusion Robotics, LLC | 2023 | 0 | — |
| +4 | K221403 | Cortera Spinal Fixation System | Surgalign Spine Technologies | 2022 | 3 | 2 |
| +4 | K220862 | E-GPS Navigated Instruments | Precision Spine, Inc. | 2022 | 7 | — |
| +4 | K220038 | Camber Spine Navigation System | Camber Spine Technologies | 2022 | 0 | — |
| +4 | K212088 | Integrity Implants Navigated Instruments | Integrity Implants, Inc. | 2021 | 0 | — |
| +4 | K211616 | ExcelsiusHub | Globus Medical, Inc. | 2021 | 9 | Class I |
| +4 | K202836 | GX Navigation Instrument System | Life Spine, Inc. | 2021 | 1 | — |
| +4 | K210963 | ENNOVATE Spinal System | Aesculap Implant Systems, LLC | 2021 | 0 | — |
| +4 | K201569 | CUVIS-spine | Curexo, Inc. | 2021 | 2 | — |
| +4 | K203673 | MySpine Pedicle Screw Placement Guides Extension (MySpine Low Profile Guides, MySpine MC… | Medacta International S.A. | 2021 | 3 | — |
| +4 | K210275 | Polaris Spinal System | Zimmer Biomet Spine, Inc. | 2021 | 0 | — |
| +4 | K202184 | Practical Navigation Surgical Guidance System (PNSGS) | Practical Navigation, LLC | 2021 | 5 | — |
| +4 | K200922 | Altus Spine HA Pedicle Screw System | Altus Partners, LLC | 2021 | 3 | — |
| +4 | K203125 | Invictus™ OCT Spinal Fixation System | Alphatec Spine, Inc. | 2020 | 0 | — |
| +4 | K203056 | Invictus™ Spinal Fixation System | Alphatec Spine, Inc. | 2020 | 61 | — |
| +4 | K202327 | Invictus™ OsseoScrew® System | Alphatec Spine, Inc. | 2020 | 0 | — |
| +4 | K200792 | MySpine S2-Alar/Alar-Iliac Pedicle Screw Placement Guides | Medacta Inernational SA | 2020 | 4 | — |
| +4 | K200047 | ExcelsiusGPS Cranial 1.0 Module | Globus Medical, Inc. | 2020 | 5 | 3 |
| +4 | K200936 | Invictus™ CT Spinal Fixation System | Alphatec Spine, Inc. | 2020 | 3 | — |
| +4 | K200303 | Reform Pedicle Screw System | Precision Spine | 2020 | 10 | — |
| +4 | K192930 | Dymaxeon Spine System | Back 2 Basics Direct, LLC | 2020 | 1 | — |
| +4 | K200070 | ARx Spinal System | Life Spine, Inc. | 2020 | 9 | — |
| +4 | K193396 | PERLA® TL posterior osteosynthesis system | Spineart | 2020 | 7 | 2 |
| +4 | K192121 | Black Diamond Pedicle Screw System | Osseus Fusion Systems | 2019 | 13 | — |
| +4 | K191575 | ARx Spinal System | Life Spine, Inc. | 2019 | 10 | — |
| +4 | K191100 | ExcelsiusGPS Spine 1.1 Interbody Module | Globus Medical, Inc. | 2019 | 42 | — |
| +4 | K191045 | Salvo™ Spine System | Spine Wave, Inc. | 2019 | 5 | — |
| +4 | K183430 | Modular Spinal Fixation System | Life Spine, Inc. | 2019 | 2 | — |
| +4 | K182974 | NuVasive Reline System | Nu Vasive, Incorporated | 2019 | 11 | — |
| +4 | K183119 | SI-LOK® Sacroiliac Joint Fixation System, Navigation Instruments, ExcelsiusGPS®… | Globus Medical, Inc. | 2019 | 2 | — |
| +4 | K182000 | AQrate Robotic Assistance System | Globus Medical, Inc. | 2019 | 1 | — |
| +4 | K180754 | C-Zero Pedicle Screw System, Freedom Pedicle Screw System | Signature Orthopaedics Pty, Ltd. | 2018 | 0 | — |
| +4 | K180498 | NuVasive Reline Fenestrated Screws, High V+ Bone Cement | Nu Vasive, Incorporated | 2018 | 41 | — |
| +4 | K180433 | Ennovate® | Aesculap Implant Systems, LLC | 2018 | 1 | 1 |
| +4 | K180198 | NuVasive® VuePoint® II OCT System | Nu Vasive, Incorporated | 2018 | 4 | — |
| +4 | K171894 | NuVasive® Precept™ Spinal System | Nu Vasive, Incorporated | 2017 | 0 | — |
| +4 | K172101 | ROMEO® 2 Posterior Osteosynthesis System | Spineart | 2017 | 9 | — |
| +4 | K170861 | Premier | Shandong Weigao Orthopaedic Device Co., Ltd. | 2017 | 0 | — |
| +4 | K171907 | Vitality® Spinal Fixation System | Zimmer Biomet Spine, Inc. | 2017 | 16 | 2 |
| +4 | K171509 | Iliad® Pedicle Screw System and Zenius® Pedicle Screw System | Medyssey USA, Inc. | 2017 | 1 | — |
| +4 | K170126 | NuVasive® Reline® 4.5-5.0 System | Nu Vasive, Incorporated | 2017 | 39 | — |
| +4 | K162419 | FIREFLY® Pedicle Screw Navigation Guide | Mighty Oak Medical, Inc. | 2016 | 7 | — |
| +4 | K150856 | Reform Pedicle Screw System | Precision Spine, Inc. | 2015 | 26 | — |
| +5 | K261284 | Invictus® Small Stature Spinal Fixation System; Invictus® 2.0 Spinal Fixation System | Alphatec Spine, Inc. | 2026 | 0 | — |
| +5 | K260369 | Dynamis Robotic Surgical System | LEM Surgical AG | 2026 | 0 | — |
| +5 | K261665 | CORUS™ Navigation System-GN | Providence Medical Technology, Inc. | 2026 | 0 | — |
| +5 | K260571 | SIMPACT Sacroiliac Joint Fixation System GX Navigation Instruments | Life Spine, Inc. | 2026 | 0 | — |
| +5 | K253966 | PERLA® TL Posterior Thoraco-lumbar Fixation System | Spineart SA | 2026 | 0 | — |
| +5 | K253615 | Invictus Bands System | Alphatec Spine, Inc. | 2026 | 0 | — |
| +5 | K252597 | Valence Robotic Navigation System; Valence Robotic Navigation Instruments (For Use with… | Alphatec Spine, Inc. | 2026 | 1 | — |
| +5 | K252327 | CMORE® CT System; CMORE® CT System Navigated Instruments | Icotec AG | 2025 | 1 | — |
| +5 | K250599 | ExcelsiusGPS™ Instruments | Globus Medical, Inc. | 2025 | 0 | — |
| +5 | K242827 | A8 INTEGR8™ Porous Pedicle Screws | Allumin8, Inc. | 2025 | 1 | — |
| +5 | K251060 | CORUS™ Navigation System-GX | Providence Medical Technology, Inc. | 2025 | 0 | — |
| +5 | K250582 | COLONNADE Posterior Screw Fixation System | CG Bio Co., Ltd. | 2025 | 0 | — |
| +5 | K242297 | Reform Pedicle Screw System | Precision Spine, Inc. | 2024 | 0 | — |
| +5 | K243106 | CarboClear® Hybrid Pedicle Screw System | CarboFix Orthopedics, Ltd. | 2024 | 0 | — |
| +5 | K241892 | Cortera™ Spinal Fixation System | Xtant Medical Holdings, Inc. | 2024 | 2 | — |
| +5 | K233256 | Robotic Integration Instruments | DePuy Synthes | 2024 | 0 | — |
| +5 | K233228 | Spine Navigation and Robotic-Assistance Device | Ecential Robotics | 2024 | 2 | 1 |
| +5 | K231923 | Liberty SI Lateral Implant System | Spinal Simplicity, LLC | 2023 | 0 | — |
| +5 | K231443 | Mini-OSTEO Pedicle Fixation System | Osteomed Indústria E Comércio DE Implantes Ltda | 2023 | 0 | — |
| +5 | K231069 | PERLA® TL Posterior Thoraco-lumbar Fixation System | Spineart SA | 2023 | 1 | — |
| +5 | K232413 | Fusion Robotic Navigation System | Alphatec Spine, Inc. | 2023 | 2 | — |
| +5 | K221926 | Invictus® Bone Cement, Invictus Spinal Fixation System | Alphatec Spine, Inc. | 2022 | 14 | — |
| +5 | K223070 | Remi Robotic Navigation System | Fusion Robotics, LLC | 2022 | 4 | — |