Devices descending from K991081
180 later devices reach Frameless Neuromate through their predicates, nearest generation first.
| Generation | Number | Device | Applicant | Decided | Own descendants | Recalls |
|---|---|---|---|---|---|---|
| +1 | K132755 | Neuromate Frameless Gen II | Renishaw Mayfield Sarl | 2014 | 1 | — |
| +1 | K101791 | Rosa Surgical Device | Medtech S.A.S | 2010 | 126 | 12 |
| +1 | K092239 | Rosa Surgical Device, Model Rosa 1.1 | Medtech S.A | 2009 | 127 | 9 |
| +1 | K072629 | Digimatch Robodoc Surgical System | Integrated Surgical Systems, Inc. | 2008 | 16 | — |
| +1 | K041477 | Pathfinder | Armstrong Healthcare Limited | 2004 | 0 | — |
| +1 | K033413 | Spineassist Device | Mazor Surgical Technologies, Ltd. | 2004 | 35 | — |
| +2 | K180206 | neuromate Gen III | Renishaw Mayfield Sarl | 2018 | 0 | — |
| +2 | K172522 | Mazor X | Mazor Robotics, Ltd. | 2017 | 0 | — |
| +2 | K151511 | ROSA Spine | Medtech S.A | 2016 | 109 | 3 |
| +2 | K151359 | ROSA Brain | Medtech S.A | 2015 | 20 | Class I |
| +2 | K143420 | SYMBIS Surgical System | Imris, Inc. | 2015 | 0 | — |
| +2 | K140585 | CTC Tcat (R)-Tplan (R) Surgical System | Curexo Technology Corporation | 2014 | 10 | — |
| +2 | K140038 | Digimatch Orthodoc Robodoc Encore Surgical System | Curexo Technology Corporation | 2014 | 0 | — |
| +2 | K103428 | The Artas System From Restoration Robotics | Restoration Robotics, Inc. | 2011 | 3 | — |
| +2 | K073467 | Spineassist System | Mazor Surgical Technologies, Ltd. | 2008 | 32 | — |
| +2 | K063607 | Spineassist System | Mazor Surgical Technologies, Ltd. | 2007 | 33 | — |
| +2 | K051676 | Spineassist Device with Additional Accessories | Mazor Surgical Technologies, Ltd. | 2005 | 34 | — |
| +3 | K191597 | Stealth Autoguide System, Midas Rex Legend Depth Stop System | Medtronic Navigation, Inc. | 2019 | 4 | 1 |
| +3 | K182848 | ROSA ONE Spine application | Medtech S.A | 2019 | 10 | — |
| +3 | K182964 | ROSA Knee System | Orthosoft Inc (D/B/A Zimmer Cas) | 2019 | 29 | — |
| +3 | K172444 | ROSA BRAIN (v3.0.0.5) | Medtech S.A | 2018 | 14 | Class I |
| +3 | K171651 | Excelsius GPS | Globus Medical, Inc. | 2017 | 69 | 1 |
| +3 | K150741 | TSolution One w/ACG surgical System | THINK Surgical, Inc. | 2015 | 9 | — |
| +3 | K123548 | The Artas System | Restoration Robotics, Inc. | 2013 | 1 | 4 |
| +3 | K123154 | Artas System From Restoration Robotics | Restoration Robotics, Inc. | 2013 | 0 | — |
| +3 | K102130 | Tenzing System | Mazor Surgical Technologies, Ltd. | 2010 | 31 | — |
| +4 | K262067 | iFuse Granite Onyx™ Implant System | SI-BONE, Inc. | 2026 | 0 | — |
| +4 | K254148 | VERTICALE GPS Instruments | Silony Medical GmbH | 2026 | 0 | — |
| +4 | K252058 | ROSA Knee System with UltraSound Imaging Platform (USIP) | Balmoral Medical, LLC | 2026 | 0 | — |
| +4 | K251780 | iGPS Navigation Instruments | SI-BONE, Inc. | 2025 | 0 | — |
| +4 | K251073 | Innovasis Navigation Instruments (Vector G-E Navigation Instruments and the Excella G-E… | Innovasis, Inc. | 2025 | 0 | 1 |
| +4 | K241525 | ExcelsiusXR™ | Globus Medical, Inc. | 2025 | 0 | — |
| +4 | K243326 | Dynamis Robotic Surgical System | LEM Surgical AG | 2025 | 1 | — |
| +4 | K243514 | Salvo® Robotic Navigation Instruments | Spine Wave, Inc. | 2025 | 0 | — |
| +4 | K243698 | Alignment System Cranial, with Alignment Software Cranial with LITT; Cirq Alignment… | Brainlab AG | 2025 | 0 | — |
| +4 | K243814 | NuVasive Pulse System | Globus Medical, Inc. | 2025 | 0 | — |
| +4 | K243671 | ExcelsiusGPS® Instruments | Globus Medical, Inc. | 2024 | 0 | — |
| +4 | K240160 | EGPS Navigated Instruments | Astura Medical | 2024 | 0 | — |
| +4 | K240721 | ExcelsiusFlex™ | Globus Medical, Inc. | 2024 | 0 | — |
| +4 | K240951 | Invictus Robotic Navigation Instruments | Alphatec Spine | 2024 | 2 | — |
| +4 | K240568 | DuraPro™ Oscillating System | Globus Medical, Inc. | 2024 | 0 | — |
| +4 | K231850 | QUARTEX® Occipito-Cervico-Thoracic Spinal System ExcelsiusGPS® Instruments | Globus Medical, Inc. | 2024 | 2 | — |
| +4 | K233638 | VERZA™ High Speed Drills | Globus Medical, Inc. | 2024 | 1 | — |
| +4 | K231494 | CoreLink Robotic Navigation Instruments | Corelink, LLC | 2023 | 0 | — |
| +4 | K232044 | Invictus Robotic Navigation Instruments | Alphatec Spine, Inc. | 2023 | 3 | — |
| +4 | K223864 | Alignment System Cranial, Alignment Software Cranial, Cirq Alignment Software Cranial… | Brainlab AG | 2023 | 1 | — |
| +4 | K223558 | CUVIS-spine | Curexo, Inc. | 2023 | 0 | — |
| +4 | K230202 | TMINI™ Miniature Robotic System | THINK Surgical, Inc. | 2023 | 10 | 1 |
| +4 | K223350 | Remi Robotic Navigation System | Fusion Robotics, LLC | 2023 | 0 | — |
| +4 | K221928 | ROSA® Knee System | Orthosoft D/B/A Zimmer Cas | 2022 | 8 | — |
| +4 | K220733 | OptiVu ROSA MxR | Orthosoft Inc (D/B/A Zimmer Cas) | 2022 | 1 | — |
| +4 | K220862 | E-GPS Navigated Instruments | Precision Spine, Inc. | 2022 | 7 | — |
| +4 | K213873 | SkyWalker Total Knee System | Microport Navibot International, LLC | 2022 | 0 | — |
| +4 | K221028 | SURGIVISIO Device | Ecential Robotics | 2022 | 7 | — |
| +4 | K213708 | ROSA® Knee System | Orthosoft Inc (D/B/A Zimmer Cas) | 2022 | 0 | — |
| +4 | K213454 | Midas Rex MR8 Depth Stop Attachment, Midas Rex MR8 Depth Stop Tool 2.4mm, Midas Rex MR8… | Medtronic Powered Surgical Solutions | 2021 | 0 | — |
| +4 | K210989 | Cirq, Cirq Robotic Alignment System, Cirq Robotic Alignment Module Cranial, Cirq Robotic… | Brainlab AG | 2021 | 2 | — |
| +4 | K211616 | ExcelsiusHub | Globus Medical, Inc. | 2021 | 9 | Class I |
| +4 | K210998 | ROSA Hip System | Orthosoft D/B/A Zimmer Cas | 2021 | 1 | — |
| +4 | K201569 | CUVIS-spine | Curexo, Inc. | 2021 | 2 | — |
| +4 | K210121 | ROSA Partial Knee System | Orthosoft D/B/A Zimmer Cas | 2021 | 1 | — |
| +4 | K202184 | Practical Navigation Surgical Guidance System (PNSGS) | Practical Navigation, LLC | 2021 | 5 | — |
| +4 | K203153 | CREO Stabilization System, Navigation Instruments, ExcelsiusGPS | Globus Medical, Inc. | 2021 | 1 | — |
| +4 | K200047 | ExcelsiusGPS Cranial 1.0 Module | Globus Medical, Inc. | 2020 | 5 | 3 |
| +4 | K192173 | ROSA ONE Spine application | Medtech S.A | 2019 | 0 | — |
| +4 | K192133 | Zimmer Biomet Universal Navigation System | Zimmer Biomet Spine, Inc. | 2019 | 0 | — |
| +4 | K191100 | ExcelsiusGPS Spine 1.1 Interbody Module | Globus Medical, Inc. | 2019 | 42 | — |
| +4 | K182417 | ROSA ONE Brain Application | Medtech S.A | 2019 | 13 | Class I |
| +4 | K183119 | SI-LOK® Sacroiliac Joint Fixation System, Navigation Instruments, ExcelsiusGPS®… | Globus Medical, Inc. | 2019 | 2 | — |
| +4 | K182000 | AQrate Robotic Assistance System | Globus Medical, Inc. | 2019 | 1 | — |
| +4 | K173358 | ARTAS System | Restoration Robotics, Inc. | 2018 | 0 | — |
| +4 | K153647 | TSolution One w/ACG+ Surgical System | THINK Surgical, Inc. | 2016 | 8 | — |
| +4 | K110911 | Renaissance System | Mazor Robotics, Ltd. | 2011 | 24 | — |
| +4 | K103400 | Fluoromap Software, 9 Fluorodisc (Belt), 12 Fluoro Disc (Belt), Close Tube Clip | Stryker Corporation | 2011 | 5 | — |
| +5 | K260369 | Dynamis Robotic Surgical System | LEM Surgical AG | 2026 | 0 | — |
| +5 | K261665 | CORUS™ Navigation System-GN | Providence Medical Technology, Inc. | 2026 | 0 | — |
| +5 | K253739 | SCRIPT™ Rods, CREO™ Stabilization System, REVERE® Stabilization System, REVERE® 4.5… | Globus Medical, Inc. | 2026 | 0 | — |
| +5 | K252597 | Valence Robotic Navigation System; Valence Robotic Navigation Instruments (For Use with… | Alphatec Spine, Inc. | 2026 | 1 | — |
| +5 | K252327 | CMORE® CT System; CMORE® CT System Navigated Instruments | Icotec AG | 2025 | 1 | — |
| +5 | K250599 | ExcelsiusGPS™ Instruments | Globus Medical, Inc. | 2025 | 0 | — |
| +5 | K251060 | CORUS™ Navigation System-GX | Providence Medical Technology, Inc. | 2025 | 0 | — |
| +5 | K242575 | Stereotaxic Guiding Surgical Devices, NaoTrac S | Brain Navi Biotechnology Co., Ltd. | 2025 | 0 | — |
| +5 | K233256 | Robotic Integration Instruments | DePuy Synthes | 2024 | 0 | — |
| +5 | K233228 | Spine Navigation and Robotic-Assistance Device | Ecential Robotics | 2024 | 2 | 1 |
| +5 | K231923 | Liberty SI Lateral Implant System | Spinal Simplicity, LLC | 2023 | 0 | — |
| +5 | K232533 | ROSA Partial Knee System | Orthosoft D/B/A Zimmer Cas | 2023 | 0 | — |
| +5 | K232802 | TMINI™ Miniature Robotic System | THINK Surgical, Inc. | 2023 | 9 | — |
| +5 | K231886 | SURGIVISIO Device | Ecential Robotics | 2023 | 6 | — |
| +5 | K230567 | OptiVu™ ROSA® MxR | Orthosoft Inc (D/B/A Zimmer Cas) | 2023 | 0 | — |
| +5 | K231162 | ROSA Hip System | Orthosoft Inc (D/B/A Zimmer Cas) | 2023 | 0 | — |
| +5 | K230243 | ROSA® Knee System | Orthosoft D/B/A Zimmer Cas | 2023 | 6 | — |
| +5 | K230180 | Rosa Knee System | Orthosoft Inc (D/B/A Zimmer Cas) | 2023 | 0 | — |
| +5 | K223070 | Remi Robotic Navigation System | Fusion Robotics, LLC | 2022 | 4 | — |
| +5 | K222270 | HEDRON Cervical Spacers, HEDRON Lumbar Spacers, SABLE Expandable Spacer, ExcelsiusGPS… | Globus Medical, Inc. | 2022 | 23 | — |
| +5 | K222698 | CUVIS-spine | Curexo, Inc. | 2022 | 0 | — |
| +5 | K212962 | TRELLIS™ SI Joint Fusion System | Orthofundamentals, LLC | 2022 | 0 | — |
| +5 | K200511 | ROSA ONE Brain application | Medtech S.A | 2020 | 5 | Class I |
| +5 | K182359 | HipCheck | Stryker Corp. | 2018 | 1 | — |
| +5 | K173946 | ADAPT for Gamma3 | Stryker GmbH | 2018 | 2 | — |
| +5 | K162195 | TSolution One Cup1 Surgical System | THINK Surgical, Inc. | 2016 | 7 | — |